assoc_id	FEATURE	Drug id	Drug name	Drug Target	N_FEATURE_pos	N_FEATURE_neg	log max.Conc.tested	log max.Conc.tested2	FEATUREpos_logIC50_MEAN	FEATUREneg_logIC50_MEAN	FEATURE_deltaMEAN_IC50	FEATUREpos_IC50_sd	FEATUREneg_IC50_sd	FEATURE_IC50_effect_size	FEATUREpos_Glass_delta	FEATUREneg_Glass_delta	FEATURE_ANOVA_pval	Tissue_ANOVA_pval	MEDIA_ANOVA_pval	MSI_ANOVA_pval	FEATURE_IC50_T_pval	ANOVA FEATURE FDR %
a1	loss_cnaLIHC10_(RB1)	192	LFM-A13	BTK	3	14	2.77258872223978	NA	3.4406455230509	5.00348669146008	-1.56284116840918	1.14273659089171	0.42355910897059	2.72222852510623	1.36763028406193	3.6897829259474	0.000659306478033711	NA	NA	NA	0.137565898758107	39.2240480121075
a2	loss_cnaLIHC10_(RB1)	175	PAC-1	CASP3 agonist	3	14	0.940007258491471	NA	0.863453896105001	2.74634531898673	-1.88289142288173	0.241268443041896	0.802841601566935	2.50191805306742	7.80413467730118	2.34528382585907	0.00132999628720354	NA	NA	NA	7.97439738757668e-06	39.5626616477208
a3	TP53_mut	200	LAQ824	HDAC	12	5	0.0237165266173161	NA	-2.36964614773581	-3.77615940909719	1.40651326136137	0.845022502177471	0.553471990449467	1.80778217119991	1.66446841088497	2.54125463552214	0.00398850715497326	NA	NA	NA	0.0017386498494935	51.9024631187225
a4	loss_cnaLIHC10_(RB1)	151	QS11	ARFGAP	3	14	2.32630161961136	NA	0.950999889723005	3.50122773266514	-2.55022784294214	1.07176925870159	1.20837673278068	2.14112697861185	2.3794560463804	2.11045758641317	0.00424856320441511	NA	NA	NA	0.0317560941952313	51.9024631187225
a5	loss_cnaLIHC10_(RB1)	1259	BMN-673	PARP1	3	13	2.30258509299405	NA	3.59050381911994	2.23869035923692	1.35181345988302	0.160369097359428	0.668403674574815	2.17409186687256	8.4293887172867	2.02245067061149	0.00436207274546431	NA	NA	NA	1.52985901790007e-05	51.9024631187225
a6	loss_cnaLIHC7_(CDKN2A)	1194	SB-505124	TGFR1 (ALK5)	4	12	2.30258509299405	NA	4.94388037644046	3.52246015604592	1.42142022039454	0.540231806965876	0.914787385690418	1.67509774509005	2.63113019645718	1.55382577703753	0.0116109334871311	NA	NA	NA	0.00430509509564529	91.0416503679971
a7	TP53_mut	190	Bleomycin	DNA damage	12	5	4.15888308335967	NA	2.25173279139149	-0.686035879444483	2.93776867083597	2.07674727994011	1.67694930814091	1.48518320999101	1.41460094794042	1.75185299673299	0.0137291663342443	NA	NA	NA	0.0129860356017833	91.0416503679971
a8	TP53_mut	1072	BMS-708163	g-secretase	11	5	1.6094379124341	NA	3.89324930517313	3.11428566066433	0.778963644508796	0.467759982089731	0.616052811629078	1.51399315933326	1.66530629881751	1.26444296625953	0.0139857552374537	NA	NA	NA	0.0442282520611104	91.0416503679971
a9	loss_cnaLIHC7_(CDKN2A)	1054	PD-0332991	CDK4, CDK6	4	10	1.38629436111989	0.693147180559945	0.816724885267867	2.41792995312056	-1.60120506785269	0.731811807857638	1.02366356887734	1.66955093550324	2.18800113725984	1.56419073271188	0.01540107568323	NA	NA	NA	0.0113922910226344	91.0416503679971
a10	TP53_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	11	5	2.30258509299405	NA	1.25540309420134	-0.117329262512328	1.37273235671366	0.883472164613469	1.15901708652064	1.41487046973594	1.55379242459127	1.18439354577126	0.0200489489861988	NA	NA	NA	0.0551556092040537	91.0416503679971
a11	TP53_mut	1047	Nutlin-3a	MDM2	10	4	2.07944154167984	1.38629436111989	4.5374953499252	3.12145651327039	1.41603883665481	0.643963179008968	1.44538852927179	1.55122065659586	2.19894379494498	0.979694253813013	0.022300768565327	NA	NA	NA	0.14277525375239	91.0416503679971
a12	loss_cnaLIHC7_(CDKN2A)	1039	SL 0101-1	RSK, AURKB, PIM3	4	7	2.30258509299405	NA	4.9890182989091	4.37426997599089	0.614748322918206	0.445568280449291	0.32335843357843	1.66768089652133	1.37969498703615	1.90113588847869	0.0260160072245405	NA	NA	NA	0.0616432301362313	91.0416503679971
a13	loss_cnaLIHC7_(CDKN2A)	281	CH5424802	ALK	4	13	1.63315443905142	NA	4.43878353247316	3.87106518112283	0.567718351350335	0.37946003539511	0.413171525542515	1.39607611910079	1.49612158961405	1.37405004036736	0.0274875278109853	NA	NA	NA	0.0470340265067458	91.0416503679971
a14	loss_cnaLIHC10_(RB1)	271	VNLG/124	HDAC, RAR 	3	14	1.63315443905142	NA	3.1441977948395	3.83587088488218	-0.691673090042681	0.513996329378373	0.435424683833508	1.54840587111733	1.34567710022208	1.58850225015528	0.027915034222395	NA	NA	NA	0.130161632351203	91.0416503679971
a15	loss_cnaLIHC7_(CDKN2A)	274	PXD101, Belinostat	HDAC	4	13	2.99573227355399	NA	1.84937092087992	-0.411338552288672	2.26070947316859	2.89507882641195	1.11971161011967	1.38112859890421	0.780880110256077	2.01901047799886	0.0289328747602008	NA	NA	NA	0.216544443928361	91.0416503679971
a16	TP53_mut	167	OSU-03012	PDPK1 (PDK1)	12	5	2.77258872223978	NA	1.81590149441526	0.936677239723781	0.879224254691483	0.781617809824563	0.356097179992751	1.26664206608978	1.12487745755029	2.46905705546273	0.0310364356103633	NA	NA	NA	0.00631034276413038	91.0416503679971
a17	loss_cnaLIHC10_(RB1)	1495	AZD-2281	PARP1, PARP2	3	13	2.30258509299405	NA	4.46291583203934	3.54965804522069	0.913257786818643	0.234316219585685	0.65648263683103	1.48689794185176	3.89754404724288	1.39113776295306	0.0358621161088254	NA	NA	NA	0.00231123365362493	91.0416503679971
a18	loss_cnaLIHC7_(CDKN2A)	1199	Tamoxifen	ER	4	12	1.6094379124341	NA	4.21184162344067	3.46633666110464	0.745504962336033	0.435709591337673	0.595106366842504	1.32006188762323	1.71101342994827	1.25272556953391	0.0383241993601694	NA	NA	NA	0.0306522739234201	91.0416503679971
a19	loss_cnaLIHC7_(CDKN2A)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	13	2.32630161961136	NA	5.20479452776336	4.6260019917487	0.578792536014656	0.375415674497144	0.461801970544548	1.29813197017218	1.54173779981331	1.25333492044686	0.0383556515339652	NA	NA	NA	0.0429606519064287	91.0416503679971
a20	TP53_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	5	1.6094379124341	NA	1.4089265634809	0.560166876770762	0.848759686710139	0.62488318361359	0.785264623034131	1.25133654391644	1.35826936772712	1.08085817419187	0.0397772935306022	NA	NA	NA	0.0753382738317822	91.0416503679971
a21	TP53_mut	1020	Lenalidomide	TNFA	10	4	1.6094379124341	NA	4.28674970450884	3.73231322829244	0.554436476216397	0.314555492289884	0.606567056039943	1.36003365559572	1.76260306943058	0.914056361445199	0.0402794057414272	NA	NA	NA	0.163867548401541	91.0416503679971
a22	TP53_mut	193	GW-2580	CSF1R (cFMS)	12	5	2.99573227355399	NA	4.97653455553355	5.4802431546978	-0.503708599164248	0.452535904131329	0.376758795000006	1.16162149882451	1.11307985635118	1.33695246361599	0.0454012637431167	NA	NA	NA	0.0422348328396354	91.0416503679971
a23	loss_cnaLIHC7_(CDKN2A)	1373	Dabrafenib	BRAF	3	12	2.30258509299405	NA	4.79706852536671	3.50793824924434	1.28913027612238	0.562584333933199	0.95193285277254	1.42756633058242	2.29144360830255	1.35422395851528	0.0455187835048269	NA	NA	NA	0.0264553034361941	91.0416503679971
a24	loss_cnaLIHC10_(RB1)	255	CP724714	ERBB2	3	14	2.32630161961136	NA	3.35065580232431	4.3632549858583	-1.01259918353399	0.623184869378702	0.750727246781889	1.3776832479747	1.62487767802116	1.34882434049737	0.0468796081672988	NA	NA	NA	0.0813128797097881	91.0416503679971
a25	loss_cnaLIHC10_(RB1)	1199	Tamoxifen	ER	3	13	1.6094379124341	NA	3.00594347473893	3.80196738483089	-0.796023910091952	0.762661586108641	0.534219975183319	1.39052422667207	1.04374459732991	1.49006766326698	0.047619030860713	NA	NA	NA	0.204240981036613	91.0416503679971
a26	loss_cnaLIHC10_(RB1)	155	AP-24534	ABL	3	14	-0.669430653942629	NA	-1.42850747625807	0.297254378680518	-1.72576185493858	0.953202750561679	1.29950324550306	1.37090769632955	1.81048769941303	1.32801657934337	0.0478368664617091	NA	NA	NA	0.0596950006285028	91.0416503679971
a27	loss_cnaLIHC7_(CDKN2A)	312	AV-951	VEGFR	4	13	-2.05572501506252	NA	0.817372976429791	0.255084935821085	0.562288040608706	0.378982359786074	0.492201390871564	1.19195373136796	1.48367866231585	1.14239425372821	0.0546063574049533	NA	NA	NA	0.0496867999207613	91.0416503679971
a28	TP53_mut	164	JQ12	HDAC	11	5	1.63315443905142	NA	1.09790012848177	-0.73275735386824	1.83065748235001	1.84346758547375	0.892838028629309	1.12346878019553	0.993051083065045	2.05038027464001	0.0560704574065048	NA	NA	NA	0.0183063218521301	91.0416503679971
a29	loss_cnaLIHC7_(CDKN2A)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	13	2.77258872223978	NA	5.48170892602021	4.47096672755341	1.0107421984668	0.500206937496929	0.946417999659429	1.15439384333498	2.02064810121311	1.06796595038399	0.0617335171538117	NA	NA	NA	0.0189148362463744	91.0416503679971
a30	loss_cnaLIHC7_(CDKN2A)	1175	AG-014699	PARP1, PARP2	4	11	1.6094379124341	NA	4.34671318191401	3.55664439212206	0.790068789791955	0.513097455906694	0.720313956034438	1.16505567143914	1.53980258661744	1.0968394866893	0.0673944512901475	NA	NA	NA	0.0480070964588086	91.0416503679971
a31	loss_cnaLIHC7_(CDKN2A)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	13	0.940007258491471	NA	2.53946642905603	1.49773139179225	1.04173503726378	1.12048675557555	0.86861433316118	1.12681535451574	0.929716511221665	1.19930675501584	0.0674960267554047	NA	NA	NA	0.159755158311311	91.0416503679971
a32	TP53_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	12	5	2.77258872223978	NA	1.36581499601904	-0.355149534532003	1.72096453055104	1.63655374442723	1.73987924419175	1.03377724400803	1.05157837706904	0.989128720453529	0.0711408463559818	NA	NA	NA	0.0997693433043967	91.0416503679971
a33	TP53_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	5	0	NA	-1.38305180720968	-3.00117554839506	1.61812374118539	1.45526836892581	1.77879959671307	1.04086738990586	1.11190745001885	0.909671749518842	0.0741451579263058	NA	NA	NA	0.120950184171443	91.0416503679971
a34	TP53_mut	1031	Elesclomol	HSP70	10	4	-1.6094379124341	NA	-3.81268591224083	-2.29645313185973	-1.5162327803811	0.743335167115583	2.30210099540196	1.14967525560737	2.03977000881668	0.658630000772994	0.075806557936871	NA	NA	NA	0.280900200629606	91.0416503679971
a35	loss_cnaLIHC10_(RB1)	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	14	2.77258872223978	NA	-0.809530489726858	1.21733026776779	-2.02686075749464	0.345079222583701	1.78961732408873	1.21310705005132	5.87360995634276	1.13256657175395	0.0758892788592977	NA	NA	NA	0.00139161513655305	91.0416503679971
a36	loss_cnaLIHC7_(CDKN2A)	286	KIN001-236	TIE2	4	13	2.32630161961136	NA	4.95947491559464	4.10935705599923	0.850117859595409	0.586051726344307	0.830188706353758	1.07959682139936	1.45058502753384	1.02400557016631	0.078502180639101	NA	NA	NA	0.0556914605866469	91.0416503679971
a37	loss_cnaLIHC10_(RB1)	135	Gemcitabine	DNA replication	3	14	0.0237165266173161	NA	-4.45344913963563	-2.04060680381551	-2.41284233582012	0.65949301668131	2.16362723847727	1.18942924129789	3.65863212314511	1.11518393414119	0.0811937301351248	NA	NA	NA	0.00449197340479307	91.0416503679971
a38	TP53_mut	1219	PFI-1	BRD2, BRD3, BRD4	11	5	2.30258509299405	NA	2.85621441218404	2.23423502971143	0.621979382472612	0.61047030645994	0.638882866820922	1.00526577940221	1.01885280232451	0.973542122936523	0.083455174054912	NA	NA	NA	0.107149121380401	91.0416503679971
a39	loss_cnaLIHC7_(CDKN2A)	1502	Bicalutamide	ANDR (androgen receptor)	3	12	2.30258509299405	NA	4.8534494530899	4.24541641535902	0.608033037730878	0.514805399694199	0.501084932113735	1.208284426202	1.1810929685121	1.21343309040645	0.0838930450165944	NA	NA	NA	0.162255805265328	91.0416503679971
a40	loss_cnaLIHC7_(CDKN2A)	196	Phenformin	AAPK1 (AMPK) agonist	4	12	8.29404964010203	NA	8.29546768028544	9.26601512766938	-0.970547447383939	0.71431225286434	0.957684807820179	1.06533769021121	1.35871594459162	1.01343097380133	0.0862610851733786	NA	NA	NA	0.0687950407230743	91.0416503679971
a41	TP53_mut	309	Y-39983	ROCK	12	5	2.99573227355399	NA	3.85465059372505	5.00653519371662	-1.15188459999156	1.28564393826865	0.826857446570639	0.975462423416183	0.895959266562395	1.39308729064359	0.0867906902637769	NA	NA	NA	0.0486663891857885	91.0416503679971
a42	loss_cnaLIHC10_(RB1)	177	GSK-650394	SGK3	3	14	2.77258872223978	NA	1.37778205589327	2.93002467900788	-1.55224262311461	1.24656970927503	1.34811458960626	1.16270973772567	1.24521124776676	1.15141742036036	0.0875755987871569	NA	NA	NA	0.146454129613849	91.0416503679971
a43	loss_cnaLIHC10_(RB1)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	13	2.30258509299405	NA	-0.18833503463185	1.06059944827297	-1.24893448290482	1.47148187205282	0.979944580071043	1.17363769782038	0.848759680037693	1.27449501564086	0.088253663642515	NA	NA	NA	0.275645991385637	91.0416503679971
a44	TP53_mut	225	Genentech Cpd 10	AURKA, AURKB	12	5	2.32630161961136	NA	2.21177697191617	3.90350836162832	-1.69173138971215	1.68375357241398	1.93264069771021	0.964729618142395	1.00473811454887	0.875347079111245	0.0899846656446613	NA	NA	NA	0.133766442086186	91.0416503679971
a45	TP53_mut	194	AUY922	HSP90	12	5	-1.36257783450257	NA	-2.27919433546436	-4.05101062766154	1.77181629219718	2.11318553437009	0.64197365541981	0.963080143526842	0.8384575151492	2.75995171645872	0.0904846689731552	NA	NA	NA	0.0194526519144847	91.0416503679971
a46	loss_cnaLIHC7_(CDKN2A)	186	Bexarotene	Retinioic acid X family agonist	4	13	2.07944154167984	NA	3.89662580089321	2.831242464836	1.0653833360572	1.22841127602744	0.986946812351686	1.02466758291869	0.867285539337073	1.0794739115866	0.0933084036475013	NA	NA	NA	0.183834774168347	91.0416503679971
a47	TP53_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	4	-1.38629436111989	0.693147180559945	-1.56962203062718	-2.44128312459064	0.871661093963457	0.86316771298318	0.624189292049904	1.07604531346993	1.00983978067359	1.39646915617669	0.0939624211256408	NA	NA	NA	0.0694832020457856	91.0416503679971
a48	loss_cnaLIHC7_(CDKN2A)	276	CAY10603	HDAC6	4	13	2.99573227355399	NA	1.89200656632013	0.503242256260351	1.38876431005978	2.36234757030538	0.962031269891442	1.01923969327977	0.58787467497014	1.44357502040083	0.0948980773589976	NA	NA	NA	0.32749187255813	91.0416503679971
a49	loss_cnaLIHC7_(CDKN2A)	1020	Lenalidomide	TNFA	4	10	1.6094379124341	NA	4.46013207354545	3.99562216640763	0.464509907137812	0.369539330395245	0.452941038168808	1.07129364582614	1.25699720958251	1.02554166656167	0.0952598349530008	NA	NA	NA	0.0881072547022388	91.0416503679971
a50	loss_cnaLIHC10_(RB1)	150	Bicalutamide	ANDR (androgen receptor)	3	14	0.0237165266173161	NA	2.26333761564654	2.62823640718896	-0.364898791542418	0.330002215881818	0.323012686902148	1.1263930618253	1.10574648890569	1.12967324919024	0.0969627035539765	NA	NA	NA	0.183001934015889	91.0416503679971
a51	TP53_mut	229	LY317615	PRKCB (PKCbeta)	12	5	2.99573227355399	2.32630161961136	3.67302164223679	5.11010500840012	-1.43708336616333	1.67501767246374	1.01521431180377	0.940991322948446	0.857951166598475	1.41554679583861	0.0974212842517265	NA	NA	NA	0.0503775816540994	91.0416503679971
a52	TP53_mut	157	JNK-9L	JNK	12	5	1.63315443905142	NA	-0.0132605341169279	-1.15649142514458	1.14323089102765	1.21207259113672	1.24183934705906	0.937011979147145	0.943203319163824	0.92059483679194	0.0987195891548048	NA	NA	NA	0.122883181970214	91.0416503679971
a53	loss_cnaLIHC10_(RB1)	202	GSK-1904529A	IGF1R	3	14	0.0237165266173161	NA	0.936457212184366	1.79632945870362	-0.859872246519252	1.0893291519962	0.717508716147446	1.10604710560045	0.789359437359711	1.19841365988724	0.102600423300949	NA	NA	NA	0.302701339649135	91.0416503679971
a54	loss_cnaLIHC10_(RB1)	165	DMOG	Prolyl-4-Hydroxylase	3	14	8.29404964010203	NA	4.34837822702564	5.2973709783144	-0.948992751288763	0.254344385466565	0.917582696032085	1.1044342574588	3.73113308378303	1.03423130731705	0.10305939438689	NA	NA	NA	0.00549369562978815	91.0416503679971
a55	loss_cnaLIHC7_(CDKN2A)	273	CUDC-101	HDAC, EGFR	4	13	1.63315443905142	NA	0.699556095283162	-0.99159088360646	1.69114697888962	2.81323050730195	1.30727452578042	0.984619411607714	0.601140565801531	1.29364333622277	0.105610255919426	NA	NA	NA	0.319307282770645	91.0416503679971
a56	loss_cnaLIHC7_(CDKN2A)	329	QL-XI-92	DDR1	4	13	2.32630161961136	NA	4.83704885397372	4.05626140885874	0.78078744511498	0.631946215605204	0.829631744133282	0.983307823585033	1.23552831844595	0.941125325346211	0.106036119218587	NA	NA	NA	0.0886464477300734	91.0416503679971
a57	TP53_mut	1023	GW 441756	NTRK1	10	4	0.693147180559945	NA	1.98970336821725	2.90561854918986	-0.915915180972613	0.990020163323139	0.456199334155925	1.03235914849804	0.925148006984239	2.00770828100236	0.106513634869643	NA	NA	NA	0.0367175994794848	91.0416503679971
a58	TP53_mut	1005	Cisplatin	DNA crosslinker	10	4	1.79175946922805	2.30258509299405	2.66502488637429	3.61697898674415	-0.951954100369862	0.88929295248495	1.06303686878878	1.01730783945595	1.07046176145872	0.895504312521644	0.111173738595659	NA	NA	NA	0.176795249351502	91.0416503679971
a59	loss_cnaLIHC10_(RB1)	1091	BMS-536924	IGF1R	3	13	1.38629436111989	NA	1.32890099691347	2.1825626277954	-0.853661630881934	1.11449663238443	0.718029292709294	1.08471396111302	0.76596160641199	1.18889527147405	0.112480861418061	NA	NA	NA	0.314141794595301	91.0416503679971
a60	loss_cnaLIHC7_(CDKN2A)	328	SNX-2112	HSP90	4	13	0.940007258491471	NA	0.568875064387104	-0.970715586150808	1.53959065053791	2.31046840616487	1.37716352791686	0.957595326204058	0.666354340284386	1.11794323573668	0.114692561736794	NA	NA	NA	0.279918964105221	91.0416503679971
a61	loss_cnaLIHC7_(CDKN2A)	256	JW-7-24-1	LCK	4	13	2.32630161961136	NA	3.1082802104725	1.71127672420828	1.39700348626422	2.0798504304167	1.25667911214132	0.957537112101545	0.671684591273388	1.11166285232815	0.114712836614869	NA	NA	NA	0.276883138462178	91.0416503679971
a62	loss_cnaLIHC7_(CDKN2A)	258	STF-62247	stimulates autophagy	4	13	2.32630161961136	NA	4.98873540439578	4.4543125930013	0.534422811394476	0.543683511014729	0.563876724388036	0.954503120976497	0.982966745482186	0.947765332882776	0.115773827350065	NA	NA	NA	0.147134452091938	91.0416503679971
a63	loss_cnaLIHC10_(RB1)	277	ABT-869	VEGFR and PDGFR family	3	14	0.0237165266173161	NA	2.02473314656349	2.39400785446828	-0.369274707904794	0.258893415708922	0.359979272687029	1.06052209723098	1.42635805122203	1.02582214011485	0.116264100021488	NA	NA	NA	0.108164925560861	91.0416503679971
a64	loss_cnaLIHC7_(CDKN2A)	265	Tubastatin A	HDAC6	4	13	2.99573227355399	NA	5.493171555409	4.60879766071668	0.884373894692315	0.669064255667757	0.98347814475965	0.951813418725933	1.32180711673152	0.899230856734946	0.116721516185667	NA	NA	NA	0.0770447079435344	91.0416503679971
a65	loss_cnaLIHC7_(CDKN2A)	301	PHA-793887	CDK-pan	4	13	2.32630161961136	NA	4.66973843069722	3.41032076128323	1.25941766941398	1.09152972225017	1.37680278904551	0.9507391851037	1.15380978066059	0.914740788902014	0.11710188316615	NA	NA	NA	0.105364185929719	91.0416503679971
a66	loss_cnaLIHC7_(CDKN2A)	1019	Bosutinib	SRC, ABL, TEC	4	10	0.693147180559945	NA	1.19897340605892	2.17950399676031	-0.980530590701396	0.694025173088712	1.07172590427289	0.989544314028458	1.41281703996068	0.914907987939911	0.120247436955345	NA	NA	NA	0.074704594695881	91.0416503679971
a67	TP53_mut	262	VX-11e	ERK	12	5	1.63315443905142	NA	3.1831444291582	2.00522497806359	1.1779194510946	1.08304687145305	1.90204863969137	0.871950196327641	1.08759785208028	0.619289868047609	0.122199920797794	NA	NA	NA	0.249125422171549	91.0416503679971
a68	TP53_mut	186	Bexarotene	Retinioic acid X family agonist	12	5	2.07944154167984	NA	3.35039256752523	2.43758888722762	0.912803680297614	1.07678815392917	0.999087066650232	0.863884734963556	0.847709623259521	0.913637770688082	0.125422966330366	NA	NA	NA	0.131511074274705	91.0416503679971
a69	TP53_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	12	5	1.63315443905142	NA	0.860622833711627	-0.659083583200899	1.51970641691253	1.75380019803905	1.8000812346254	0.860409047642968	0.866521978165889	0.844243241738356	0.126834243330011	NA	NA	NA	0.151915570366533	91.0416503679971
a70	loss_cnaLIHC10_(RB1)	1133	JNJ-26854165	MDM2	3	12	2.30258509299405	NA	2.06037601724649	2.63277153943949	-0.572395522193008	0.481951502338688	0.554195722957408	1.05276584160768	1.18766207681776	1.03284002110027	0.126880350413331	NA	NA	NA	0.159913089989212	91.0416503679971
a71	TP53_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	12	5	2.07944154167984	NA	2.56247660542651	1.2228543087132	1.3396222967133	1.73246867088866	0.968339937394723	0.85565943844078	0.773244745618489	1.38342150827477	0.128784790205342	NA	NA	NA	0.0635428277411267	91.0416503679971
a72	loss_cnaLIHC7_(CDKN2A)	231	FMK	RSK	4	13	2.99573227355399	2.32630161961136	5.47466598488149	4.79490431418197	0.679761670699527	0.617961224561718	0.772905918216292	0.913043062127168	1.1000069966876	0.879488246471546	0.131143787995606	NA	NA	NA	0.118913779125664	91.0416503679971
a73	loss_cnaLIHC7_(CDKN2A)	257	NPK76-II-72-1	PLK3	4	13	2.32630161961136	NA	4.08917920225791	2.89276491185661	1.1964142904013	1.51083484862378	1.2602719141665	0.910366426865279	0.791889524848538	0.949330280991442	0.132193499943978	NA	NA	NA	0.218136247131247	91.0416503679971
a74	loss_cnaLIHC7_(CDKN2A)	179	5-Fluorouracil	DNA antimetabolite	4	13	3.46573590279973	NA	5.01999497395731	3.91162621502689	1.10836875893042	1.17511249936486	1.23110139656136	0.908417691368168	0.943202254702834	0.900306637638665	0.1329622513986	NA	NA	NA	0.161358627216963	91.0416503679971
a75	loss_cnaLIHC10_(RB1)	176	IPA-3	PAK1, PAK2, PAK3	3	14	3.46573590279973	NA	2.81165711495161	4.12764738436684	-1.31599026941523	1.01519002900629	1.3447589732406	1.00793363060161	1.29629944327111	0.978606795419968	0.133982137785351	NA	NA	NA	0.133771555155176	91.0416503679971
a76	loss_cnaLIHC7_(CDKN2A)	300	CX-5461	RNA Pol I	4	13	2.32630161961136	NA	4.92633590354517	3.45589483704906	1.47044106649611	0.904360132658921	1.76097224683504	0.904242054846967	1.6259463607411	0.835016604684657	0.134622332469315	NA	NA	NA	0.0503799893262328	91.0416503679971
a77	TP53_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	5	1.38629436111989	NA	1.69462029335148	0.888202650004389	0.806417643347091	0.786045188631048	1.25209524633515	0.855156566754474	1.02591766352711	0.644054552325354	0.135174416210212	NA	NA	NA	0.237247147777154	91.0416503679971
a78	TP53_mut	1018	ABT-888	PARP1, PARP2	10	4	1.6094379124341	NA	4.26798602947667	3.90377838023369	0.364207649242972	0.261611710713747	0.621045514126613	0.947497602039261	1.39216875364377	0.586442766203961	0.135233309288962	NA	NA	NA	0.329916170035747	91.0416503679971
a79	TP53_mut	1192	GSK269962A	ROCK1, ROCK2	11	5	1.6094379124341	NA	1.79404053919999	0.968373892688867	0.825666646511126	0.921413924324275	1.06927785358641	0.854751169827969	0.896086573812778	0.772172212995713	0.135345233611075	NA	NA	NA	0.180043086913837	91.0416503679971
a80	TP53_mut	163	JQ1	BRD4	12	5	0.940007258491471	NA	0.44615143163425	-0.975429032381325	1.42158046401558	1.91769765611256	0.799129706561291	0.839545557609794	0.741295406752136	1.77891079801392	0.135594690551749	NA	NA	NA	0.0476675321470369	91.0416503679971
a81	loss_cnaLIHC7_(CDKN2A)	254	AC220	FLT3	4	13	0.0237165266173161	NA	2.89434838370064	2.34826139813441	0.546086985566233	0.374608221838518	0.651740663771182	0.900345795262896	1.45775493897631	0.837890001225944	0.13618723320925	NA	NA	NA	0.0646905350790415	91.0416503679971
a82	loss_cnaLIHC7_(CDKN2A)	1243	piperlongumine	Increases ROS levels	4	12	2.30258509299405	NA	1.64783915332266	1.20093377394493	0.446905379377721	0.562796848822673	0.470141971122166	0.909325109931907	0.794079391724761	0.950575372607167	0.137578740208486	NA	NA	NA	0.218295079034192	91.0416503679971
a83	loss_cnaLIHC10_(RB1)	1239	YK 4-279	RNA helicase A	3	12	2.30258509299405	NA	1.70107547003987	1.09478967540403	0.60628579463584	0.83993171174639	0.544200934511836	1.01170150727315	0.721827484493052	1.11408444232036	0.14104985491298	NA	NA	NA	0.33720600028973	91.0416503679971
a84	loss_cnaLIHC10_(RB1)	1043	JNK Inhibitor VIII	JNK	3	11	2.30258509299405	NA	3.67126568360285	4.38285255031643	-0.711586866713583	0.914984327293791	0.64344374840519	1.0222543169362	0.777703885724701	1.10590376933071	0.142519278248569	NA	NA	NA	0.308707287691871	91.0416503679971
a85	TP53_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	12	5	2.77258872223978	NA	-0.797504399545002	-2.42318593749666	1.62568153795165	2.19919578446904	1.20137556606111	0.819878919862986	0.739216376019086	1.35318345393164	0.144318943042121	NA	NA	NA	0.0717454255538693	91.0416503679971
a86	TP53_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	4	1.6094379124341	NA	1.19423973331204	0.282255961434584	0.911983771877459	0.931434897703111	1.15382690568636	0.919598604612804	0.979117031288372	0.790399120858569	0.146053652900804	NA	NA	NA	0.22220919347742	91.0416503679971
a87	TP53_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	12	5	-0.669430653942629	NA	-4.21204213941799	-5.84549981277869	1.6334576733607	2.20479539908016	1.30502842526506	0.814797698268472	0.740865875374278	1.25166444020477	0.146648655307958	NA	NA	NA	0.0816444656332945	91.0416503679971
a88	TP53_mut	134	Etoposide	TOP2	12	5	2.77258872223978	NA	1.78753621970417	0.363139541945691	1.42439667775848	1.89697584210003	1.27858371355579	0.812304329532417	0.750877605368775	1.11404256339006	0.147803398037422	NA	NA	NA	0.0988363437798533	91.0416503679971
a89	loss_cnaLIHC10_(RB1)	1067	CCT007093	PPM1D	3	13	1.88706964903238	NA	4.03278497718734	4.37663180151402	-0.34384682432668	0.45062059427163	0.330953743461808	0.980852984569404	0.763051730652621	1.03895735014207	0.147961474526018	NA	NA	NA	0.315865568086154	91.0416503679971
a90	TP53_mut	140	Vinorelbine	Microtubules	12	5	-2.74887219562247	NA	-3.34331178246156	-4.62053470295949	1.27722292049793	1.63445365625814	1.44980803855782	0.804642937500266	0.781437219469384	0.880960021278699	0.15139957470384	NA	NA	NA	0.147684563670087	91.0416503679971
a91	TP53_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	10	4	1.6094379124341	NA	1.50811191611721	2.28797719699049	-0.779865280873279	0.429209133835453	1.55677494639934	0.904102811557265	1.8169820243673	0.500949275087595	0.152380709070463	NA	NA	NA	0.392576932330848	91.0416503679971
a92	loss_cnaLIHC7_(CDKN2A)	219	AT-7519	CDK9	4	13	2.32630161961136	NA	3.25153160300166	1.68146485182661	1.57006675117505	2.20637950276799	1.7262116664925	0.856864616951558	0.711603216584153	0.90954474567147	0.154722866121128	NA	NA	NA	0.258638106902036	91.0416503679971
a93	loss_cnaLIHC7_(CDKN2A)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	10	0.693147180559945	NA	2.42701794653416	1.29755081282825	1.12946713370591	1.20138395353946	1.28408313520802	0.893625347155014	0.940138354918367	0.879590349516533	0.15679091523422	NA	NA	NA	0.170682844109644	91.0416503679971
a94	loss_cnaLIHC10_(RB1)	261	TL-1-85	MAP3K7 (TAK1)	3	14	2.32630161961136	NA	2.00731074143928	3.17008811942035	-1.16277737798107	0.300923616795998	1.31661745267567	0.944871476457701	3.86402832174299	0.883155069544337	0.158213205840817	NA	NA	NA	0.00995992884413649	91.0416503679971
a95	loss_cnaLIHC7_(CDKN2A)	1375	Temozolomide	DNA akylating agent	4	12	3.40119738166216	NA	5.94170337018015	5.60494415492696	0.336759215253194	0.410383244500774	0.387719402788206	0.85757871160543	0.820596892699304	0.868564257634407	0.159613182764143	NA	NA	NA	0.209981034436349	91.0416503679971
a96	loss_cnaLIHC7_(CDKN2A)	272	AR-42	HDAC	4	13	1.63315443905142	NA	0.108965034928547	-0.656165449478057	0.765130484406604	1.08638329419718	0.864948633754765	0.837544934853225	0.704291467379402	0.884596442548446	0.163613304483895	NA	NA	NA	0.263324852185543	91.0416503679971
a97	TP53_mut	173	FH535	unknown 	12	5	3.46573590279973	NA	1.70392019975783	0.762334282355282	0.941585917402546	1.39222580330494	0.386722997591037	0.778916446465917	0.67631695603354	2.43478128600534	0.164016117942252	NA	NA	NA	0.0491718658183045	91.0416503679971
a98	loss_cnaLIHC7_(CDKN2A)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	13	2.32630161961136	NA	3.19567422452192	1.67435576659248	1.52131845792944	2.39469544025214	1.64548679455983	0.835811715267077	0.63528682284928	0.924540058880507	0.164431249718683	NA	NA	NA	0.302143359586479	91.0416503679971
a99	loss_cnaLIHC10_(RB1)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	14	1.63315443905142	NA	-0.954282748318746	0.706778880963662	-1.66106162928241	1.25818362674306	1.85976888342165	0.927309922071561	1.32020604463138	0.893154866762986	0.165580162112366	NA	NA	NA	0.129258121774528	91.0416503679971
a100	loss_cnaLIHC7_(CDKN2A)	230	GSK429286A	ROCK2	4	13	2.99573227355399	2.32630161961136	5.64803897170783	4.58693786597646	1.06110110573137	0.528339730023152	1.40048806982763	0.832416159101375	2.00836894413538	0.757665222997559	0.166043526154914	NA	NA	NA	0.040583617787117	91.0416503679971
a101	loss_cnaLIHC10_(RB1)	1049	PD-173074	FGFR1, FGFR3	3	11	0.693147180559945	NA	1.33918960760205	2.71356772831685	-1.3743781207148	2.42229525289912	1.13800550768719	0.958241698232531	0.567386704436578	1.20770779353081	0.166972299259615	NA	NA	NA	0.430960351696155	91.0416503679971
a102	loss_cnaLIHC7_(CDKN2A)	136	Mitomycin C	DNA crosslinker	4	13	2.77258872223978	NA	0.537051082733321	-0.33693420153143	0.873985284264751	0.706890600819215	1.1234375179084	0.829689030665996	1.23637983480314	0.777956290699573	0.167347888546373	NA	NA	NA	0.0996731601101652	91.0416503679971
a103	loss_cnaLIHC7_(CDKN2A)	1259	BMN-673	PARP1	4	12	2.30258509299405	NA	2.00079903080761	2.65594083368411	-0.655141802876504	1.16335188436191	0.64095735170349	0.836902001585881	0.563150162631872	1.02213010137931	0.169212305819474	NA	NA	NA	0.349280004809699	91.0416503679971
a104	loss_cnaLIHC7_(CDKN2A)	208	SB-715992	KIF11	4	13	-2.05572501506252	NA	0.161633022620595	-1.1208687600606	1.2825017826812	1.01276538052656	1.66852094751776	0.822334766809173	1.26633651519011	0.768645898386329	0.170907691619747	NA	NA	NA	0.0958788206043938	91.0416503679971
a105	loss_cnaLIHC10_(RB1)	170	Shikonin	unknown	3	14	2.77258872223978	NA	-1.08832129145975	0.028449673451338	-1.11677096491108	0.776214850003409	1.27546205401878	0.914823534414079	1.43873949964521	0.875581489384428	0.170989381255687	NA	NA	NA	0.107260447483593	91.0416503679971
a106	loss_cnaLIHC10_(RB1)	178	BAY 61-3606	SYK	3	14	2.07944154167984	NA	1.04288281829549	2.35921182066654	-1.31632900237105	0.277407937023396	1.54375953493457	0.913655924284356	4.74510216432643	0.85267748803044	0.171502578733713	NA	NA	NA	0.00945695571306206	91.0416503679971
a107	TP53_mut	207	AS601245	JNK 	12	5	2.07944154167984	NA	2.06798548494752	1.24693147436638	0.82105401058114	1.1821418276263	0.712252788403682	0.762301725714772	0.694547804157972	1.15275647066445	0.172619427993295	NA	NA	NA	0.10308748844243	91.0416503679971
a108	TP53_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	3	2.30258509299405	NA	2.26729247429894	1.11594028671194	1.151352187587	0.648244106237773	2.11222750748432	1.00277559127139	1.77610899429403	0.545089098360562	0.172692411296341	NA	NA	NA	0.445758353268278	91.0416503679971
a109	loss_cnaLIHC7_(CDKN2A)	192	LFM-A13	BTK	4	13	2.77258872223978	NA	4.227106089705	4.88171737621337	-0.654611286508374	1.52349831920493	0.474725519721151	0.815401922888476	0.429676408734074	1.37892584096361	0.174320513671999	NA	NA	NA	0.456066199864808	91.0416503679971
a110	loss_cnaLIHC10_(RB1)	196	Phenformin	AAPK1 (AMPK) agonist	3	13	8.29404964010203	NA	8.31682235497128	9.18642962986619	-0.869607274894911	1.11010384700029	0.919122568278729	0.916570297054958	0.783356689777043	0.946127649246447	0.174373742729885	NA	NA	NA	0.306263720941468	91.0416503679971
a111	loss_cnaLIHC7_(CDKN2A)	150	Bicalutamide	ANDR (androgen receptor)	4	13	0.0237165266173161	NA	2.77206318261895	2.4997746013161	0.272288581302852	0.402278073489854	0.315023898952902	0.814499728637222	0.676866573762487	0.864342617204292	0.174768733396938	NA	NA	NA	0.279173720868915	91.0416503679971
a112	loss_cnaLIHC10_(RB1)	301	PHA-793887	CDK-pan	3	14	2.32630161961136	NA	4.71530703481353	3.49051446535931	1.22479256945422	0.598343893878353	1.43448841407388	0.905114601205733	2.04697095096157	0.853818376947269	0.175295475894986	NA	NA	NA	0.044727995843704	91.0416503679971
a113	loss_cnaLIHC7_(CDKN2A)	1018	ABT-888	PARP1, PARP2	4	10	1.6094379124341	NA	4.40036885762814	4.06934983851889	0.331019019109251	0.278005434272391	0.422574430362704	0.845579927535072	1.1906926207238	0.78333897019072	0.178433533051219	NA	NA	NA	0.121535171839686	91.0416503679971
a114	loss_cnaLIHC10_(RB1)	238	CAL-101	PI3Kdelta	3	14	2.99573227355399	2.32630161961136	5.57578352681402	4.67579512489937	0.899988401914643	0.196919669245884	1.07421674494002	0.897633833560332	4.570332691301	0.837808948849418	0.178673827156989	NA	NA	NA	0.0106746145853624	91.0416503679971
a115	loss_cnaLIHC7_(CDKN2A)	1192	GSK269962A	ROCK1, ROCK2	4	12	1.6094379124341	NA	2.13636735642057	1.33590383074683	0.800463525673739	1.62182012225643	0.713108478185733	0.815615609339791	0.493558758267261	1.12249896076155	0.179591456969335	NA	NA	NA	0.401731328200804	91.0416503679971
a116	TP53_mut	177	GSK-650394	SGK3	12	5	2.77258872223978	NA	2.96177817893461	1.92247070531498	1.03930747361963	1.59440135339941	0.477340279798421	0.749084885342996	0.651848087938292	2.17728844098077	0.179725998544793	NA	NA	NA	0.0591897569049469	91.0416503679971
a117	loss_cnaLIHC7_(CDKN2A)	1049	PD-173074	FGFR1, FGFR3	4	10	0.693147180559945	NA	3.28660153081342	2.07204077110378	1.21456075970964	0.257725872684692	1.65744221940244	0.842766169690772	4.71260703109758	0.732792217726618	0.179775481656431	NA	NA	NA	0.0481285977931568	91.0416503679971
a118	TP53_mut	300	CX-5461	RNA Pol I	12	5	2.32630161961136	NA	4.16309427505613	2.93496903902896	1.22812523602717	1.35246734836734	2.28229217724409	0.74323824022829	0.9080627621138	0.538110434883126	0.182945297658235	NA	NA	NA	0.310130275416143	91.0416503679971
a119	loss_cnaLIHC10_(RB1)	194	AUY922	HSP90	3	14	-1.36257783450257	NA	-4.19666543655113	-2.50109920387333	-1.6955662326778	0.255563028318681	2.04969366774543	0.887525876803096	6.63463038387332	0.827229092502806	0.183323215208969	NA	NA	NA	0.00948620665166482	91.0416503679971
a120	loss_cnaLIHC7_(CDKN2A)	310	YM201636	FYV1	4	13	1.63315443905142	NA	3.26321328957651	2.23103857226377	1.03217471731275	1.1460143327947	1.32966942493416	0.797031524703476	0.900664754162075	0.776264158562463	0.183635355045372	NA	NA	NA	0.182700990998112	91.0416503679971
a121	loss_cnaLIHC7_(CDKN2A)	1006	Cytarabine	DNA synthesis	4	10	0.693147180559945	NA	-0.407020053796243	0.429192047672591	-0.836212101468834	1.05811631259517	0.996040528072355	0.826364693950605	0.790283725442164	0.839536221570383	0.18776700306116	NA	NA	NA	0.229561737319448	91.1012030491546
a122	TP53_mut	1058	GDC0941	PI3K (class 1)	10	4	1.38629436111989	0.693147180559945	0.825268387493833	1.93056842578627	-1.10530003829244	0.694657389857753	2.39468579018986	0.824864171555331	1.59114414448074	0.461563701935529	0.18851268686725	NA	NA	NA	0.426932794397224	91.1012030491546
a123	TP53_mut	133	Doxorubicin	DNA intercalating	12	5	0.0237165266173161	NA	-1.40117140297841	-2.35467328246768	0.95350187948926	1.36139292760998	1.14627211675502	0.729259819813596	0.70038697877122	0.831828555848088	0.19083317595337	NA	NA	NA	0.174167677904873	91.1012030491546
a124	loss_cnaLIHC7_(CDKN2A)	1036	PLX4720	BRAF	4	10	2.30258509299405	NA	3.44503890882468	4.11904313975213	-0.67400423092745	0.860676056642016	0.815514869847448	0.814963206451311	0.783110237267575	0.826476936041069	0.193494925628958	NA	NA	NA	0.233650253241724	91.1012030491546
a125	loss_cnaLIHC10_(RB1)	1030	KU-55933	ATM	3	11	2.30258509299405	NA	3.10045508292182	3.73621102397404	-0.635755941052222	0.559372266805091	0.734992509364054	0.897008970220366	1.13655248710024	0.86498288479471	0.193603983494876	NA	NA	NA	0.177414723884781	91.1012030491546
a126	loss_cnaLIHC7_(CDKN2A)	275	I-BET	BRD2, BRD3, BRD4	4	13	2.99573227355399	NA	4.73036331158258	3.5867245563309	1.14363875525168	1.72817312963431	1.40068257000267	0.776917422361704	0.661761680957089	0.816486747064678	0.194296182011821	NA	NA	NA	0.289673305295648	91.1012030491546
a127	TP53_mut	271	VNLG/124	HDAC, RAR 	12	5	1.63315443905142	NA	3.8190518171506	3.46123279341235	0.357819023738247	0.553218349337953	0.298592920891772	0.718210313839613	0.646795291888738	1.19835065971957	0.197261704473715	NA	NA	NA	0.108394012871715	91.1012030491546
a128	TP53_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	3	1.38629436111989	0.693147180559945	3.04102806787723	1.63799362311777	1.40303444475945	1.26753211722768	2.46247535495516	0.902459012029767	1.10690248056842	0.569765882909721	0.197717619546598	NA	NA	NA	0.430094953192778	91.1012030491546
a129	TP53_mut	1054	PD-0332991	CDK4, CDK6	10	4	1.38629436111989	0.693147180559945	1.69624087967582	2.62094756887971	-0.924706689203885	0.992934589197267	1.53259828194909	0.8028329959379	0.931286611690564	0.603358818873192	0.199747117091483	NA	NA	NA	0.325932809116155	91.1012030491546
a130	loss_cnaLIHC7_(CDKN2A)	134	Etoposide	TOP2	4	13	2.77258872223978	NA	2.40969999677257	1.04825633531448	1.36144366145809	2.70428489627731	1.4627187115449	0.764148678293722	0.503439435442708	0.930762456727007	0.201319961799689	NA	NA	NA	0.395725059117412	91.1012030491546
a131	loss_cnaLIHC7_(CDKN2A)	294	MPS-1-IN-1	MPS1	4	13	2.99573227355399	NA	4.76018456349947	4.0050268561604	0.755157707339069	1.36620312954435	0.868624470949045	0.764030347826173	0.552741895409745	0.869371900740945	0.201385995568274	NA	NA	NA	0.359217145011398	91.1012030491546
a132	TP53_mut	1039	SL 0101-1	RSK, AURKB, PIM3	8	3	2.30258509299405	NA	4.71090986917426	4.29622802472619	0.414681844448064	0.489123857302835	0.259847382839509	0.92475911428362	0.847805393780495	1.59586692741172	0.205109047386437	NA	NA	NA	0.111759291066162	91.1012030491546
a133	loss_cnaLIHC10_(RB1)	330	XMD13-2	RIPK	3	14	2.32630161961136	NA	4.60856933246752	3.81721603531385	0.791353297153678	0.296108388570039	1.00756490399922	0.838117683171553	2.67251225463509	0.785411732795219	0.207486333389374	NA	NA	NA	0.0282740298637084	91.1012030491546
a134	TP53_mut	1010	Gefitinib	EGFR	10	4	-0.693147180559945	NA	1.30974117437611	0.527545047067673	0.782196127308437	0.737103648360221	1.52994650315757	0.785076590896258	1.06117522148823	0.511257175132664	0.209198373549062	NA	NA	NA	0.389508660618446	91.1012030491546
a135	loss_cnaLIHC7_(CDKN2A)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	10	1.38629436111989	0.693147180559945	3.76992437247932	2.40144884306876	1.36847552941056	0.720671668529692	1.69212572085476	0.876593838668173	1.89888903528358	0.808731592779814	0.209913877544424	NA	NA	NA	0.075111275317195	91.1012030491546
a136	TP53_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	12	5	1.63315443905142	NA	2.42884161491127	3.19671140765567	-0.767869792744396	1.20381119439978	0.774187924318812	0.694471376042935	0.637865635671595	0.991839020764918	0.21166310509722	NA	NA	NA	0.143972537324137	91.1012030491546
a137	TP53_mut	170	Shikonin	unknown	12	5	2.77258872223978	NA	0.0830338139786296	-0.772614842760813	0.855648656739442	1.30995001901284	0.996877814129549	0.693252026521687	0.65319183504745	0.858328517910267	0.212424918076458	NA	NA	NA	0.174140426595801	91.1012030491546
a138	loss_cnaLIHC10_(RB1)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	14	0.246860077931526	2.32630161961136	2.16831977163671	1.00679624200711	1.1615235296296	0.601009303078029	1.49026994999782	0.826933265173527	1.93262154792103	0.779404784771578	0.213296020859021	NA	NA	NA	0.0572423219476696	91.1012030491546
a139	loss_cnaLIHC10_(RB1)	185	OSI-906	IGF1R	3	14	0.940007258491471	NA	0.992309770801357	2.07454341225577	-1.08223364145441	1.30228828529548	1.31154698101042	0.825933148910939	0.831024630778172	0.825158120238025	0.213821772056383	NA	NA	NA	0.284696215897252	91.1012030491546
a140	loss_cnaLIHC10_(RB1)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	14	2.07944154167984	NA	1.07653985151213	2.40245508958198	-1.32591523806985	1.35300839846165	1.64306957384433	0.824870758480946	0.979975615507929	0.806974494066964	0.214381388253973	NA	NA	NA	0.224844467270904	91.1012030491546
a141	loss_cnaLIHC7_(CDKN2A)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	10	0.693147180559945	NA	-1.32807511489367	-0.521421737640824	-0.806653377252841	1.57628505223073	0.812159249914269	0.763624816074419	0.511743339893557	0.993220698204189	0.221100593684304	NA	NA	NA	0.390368542627509	92.0470721412617
a142	TP53_mut	155	AP-24534	ABL	12	5	-0.669430653942629	NA	0.265431985611206	-0.661828990916286	0.927260976527492	1.32850155159799	1.47306900627687	0.677551478954249	0.697975079827445	0.629475586395719	0.222430117475175	NA	NA	NA	0.263879955242788	92.0470721412617
a143	TP53_mut	158	PF-562271	FAK	10	5	0.940007258491471	NA	1.70751546351852	1.0876348668583	0.619880596660218	0.876340980307665	0.910478484266711	0.698862724020502	0.707350917724504	0.680829484026153	0.224302295678014	NA	NA	NA	0.244472789738668	92.0470721412617
a144	TP53_mut	176	IPA-3	PAK1, PAK2, PAK3	12	5	3.46573590279973	NA	4.15974543579707	3.26101789928516	0.898727536511911	1.55804199289382	0.271831610680573	0.66989660431145	0.576831395181247	3.30619214690229	0.22744133019531	NA	NA	NA	0.0767810888998812	92.0470721412617
a145	loss_cnaLIHC10_(RB1)	260	NG-25	MAP3K7 (TAK1)	3	14	2.32630161961136	NA	1.80081671207561	2.67812930767769	-0.877312595602077	0.220295837719195	1.17703284023584	0.79849579956328	3.98242928547912	0.745359488377818	0.228650442328425	NA	NA	NA	0.020690953115057	92.0470721412617
a146	TP53_mut	201	Epothilone B	Microtubules	12	5	-3.44201937618241	NA	-5.53021867125949	-6.49545527634105	0.965236605081567	1.45342870323709	1.45609799967587	0.663784742047018	0.664110047456598	0.662892611140481	0.231505759580066	NA	NA	NA	0.250083709185334	92.0470721412617
a147	loss_cnaLIHC7_(CDKN2A)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	10	1.6094379124341	NA	1.25922768078672	1.91961172259872	-0.660384041811998	0.582374220967246	0.966253641309642	0.745340915265291	1.13395136329213	0.68344792048279	0.231672386492904	NA	NA	NA	0.150577403626576	92.0470721412617
a148	loss_cnaLIHC10_(RB1)	186	Bexarotene	Retinioic acid X family agonist	3	14	2.07944154167984	NA	3.7920476816628	2.92975087153232	0.862296810130482	1.07844371292227	1.09279251181956	0.790452399234174	0.799575165396353	0.789076426498121	0.233147417714166	NA	NA	NA	0.299935470472079	92.0470721412617
a149	TP53_mut	1032	Afatinib	ERBB2, EGFR	10	4	-0.693147180559945	NA	1.44305780831365	0.630910931883269	0.812146876430383	0.643536747939093	1.88528123030379	0.741639950620364	1.26200543952037	0.430782879167325	0.233860881195005	NA	NA	NA	0.456624893846315	92.0470721412617
a150	loss_cnaLIHC10_(RB1)	190	Bleomycin	DNA damage	3	14	4.15888308335967	NA	-0.120730171708521	1.71091461532864	-1.83164478703716	1.27979239407037	2.44298796850882	0.788885694428061	1.43120462000217	0.749755958951849	0.234031339948153	NA	NA	NA	0.11429640083141	92.0470721412617
a151	loss_cnaLIHC7_(CDKN2A)	333	T0901317	LXR	4	13	2.32630161961136	NA	4.71084832670271	4.20815828658639	0.50269004011632	0.821560306956426	0.681045591725654	0.706648181793415	0.611872355394821	0.738115107452042	0.235504116543733	NA	NA	NA	0.323799333954843	92.0470721412617
a152	loss_cnaLIHC7_(CDKN2A)	1013	Nilotinib	ABL	4	8	0.693147180559945	NA	3.35243238857315	3.05293394226054	0.299498446312609	0.27391560312177	0.427676289349996	0.771903639720777	1.09339680872238	0.700292379471871	0.236101797527234	NA	NA	NA	0.176062279115741	92.0470721412617
a153	loss_cnaLIHC7_(CDKN2A)	330	XMD13-2	RIPK	4	13	2.32630161961136	NA	4.46902625314998	3.79927903686127	0.669747216288712	1.03253371639743	0.928687492722184	0.704726341941986	0.648644403231205	0.721176091567184	0.236720756919065	NA	NA	NA	0.302291966709692	92.0470721412617
a154	loss_cnaLIHC10_(RB1)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	14	2.77258872223978	NA	-2.57466280025716	-0.997285291517987	-1.57737750873918	1.51424147790186	2.10437263229469	0.774896619883884	1.04169482328856	0.749571385092165	0.242040194164249	NA	NA	NA	0.205639638329866	93.504355418339
a155	loss_cnaLIHC7_(CDKN2A)	167	OSU-03012	PDPK1 (PDK1)	4	13	2.77258872223978	NA	1.96769682438204	1.43103206415953	0.536664760222508	0.795559096919941	0.773307793734358	0.689969868638943	0.674575606388313	0.693985971136946	0.246226109388593	NA	NA	NA	0.289434637961828	94.507760838242
a156	loss_cnaLIHC10_(RB1)	288	KIN001-055	JAK3, MNK1	3	14	2.32630161961136	NA	3.68875062288692	4.26772585479036	-0.578975231903438	1.0167530792692	0.712050219015389	0.762039317145347	0.569435434923471	0.813110109992011	0.249587055953843	NA	NA	NA	0.431469008128994	94.7886666862591
a157	loss_cnaLIHC7_(CDKN2A)	304	SB52334	ALK5	4	13	2.99573227355399	NA	4.93367662913042	4.22839111359577	0.705285515534646	1.27464175336148	0.97550205856994	0.676713625907788	0.553320580998284	0.722997465088465	0.255014142000154	NA	NA	NA	0.364089165104004	94.7886666862591
a158	loss_cnaLIHC7_(CDKN2A)	140	Vinorelbine	Microtubules	4	13	-2.74887219562247	NA	-2.88642248283677	-3.97513269022993	1.08871020739316	2.65349470569967	1.25174638923379	0.667317593990676	0.410292963861818	0.869753024060705	0.261387341696582	NA	NA	NA	0.478680839269237	94.7886666862591
a159	TP53_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	10	4	-1.38629436111989	0.693147180559945	-2.69924388913107	-1.91849319405633	-0.780750695074746	0.717579330854385	1.86296920313995	0.697250698272616	1.08803397966486	0.419089426577116	0.261412179185708	NA	NA	NA	0.46914296485975	94.7886666862591
a160	loss_cnaLIHC10_(RB1)	1494	SN-38	TOP1	3	13	-2.99573227355399	NA	-3.2156028645041	-4.18142179552518	0.965818931021079	1.99968328430368	1.12883310126843	0.748837699248969	0.482985950126294	0.855590547385459	0.261875664496451	NA	NA	NA	0.49436680714507	94.7886666862591
a161	loss_cnaLIHC7_(CDKN2A)	211	TL-2-105	CRAF	4	13	2.32630161961136	1.63315443905142	4.71604185293509	4.15132474160328	0.56471711133181	0.635093349926346	0.894526241131388	0.665151238985689	0.889187568091057	0.631303013109556	0.262873835611417	NA	NA	NA	0.203169203102776	94.7886666862591
a162	loss_cnaLIHC7_(CDKN2A)	1038	NU-7441	PRKDC (DNAPK)	4	10	0.693147180559945	NA	2.49254387825647	1.98790544861006	0.504638429646417	0.563132065674512	0.774266965572912	0.69389698721238	0.896128031782329	0.651762831277471	0.263592959389475	NA	NA	NA	0.21427013293843	94.7886666862591
a163	TP53_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	11	5	-2.30258509299405	NA	-1.07101806287964	0.0563181975951224	-1.12733626047476	2.1024017582814	0.477334845659615	0.62801480962487	0.536213526284481	2.36173049322836	0.263732641314426	NA	NA	NA	0.117690910080191	94.7886666862591
a164	loss_cnaLIHC10_(RB1)	222	BX-912	PDPK1 (PDK1)	3	14	2.32630161961136	NA	3.98920440478385	2.85549630701708	1.13370809776677	0.633783760128538	1.6302612529965	0.73845963458153	1.7887932274201	0.695414980686663	0.263896503309791	NA	NA	NA	0.0777273804072004	94.7886666862591
a165	loss_cnaLIHC10_(RB1)	164	JQ12	HDAC	3	13	1.63315443905142	NA	-0.542750587559298	0.772412800510476	-1.31516338806977	0.218577812118361	1.9231245758761	0.73786798899329	6.0169116678577	0.683868015919165	0.268615776935868	NA	NA	NA	0.0319417905432635	94.7886666862591
a166	TP53_mut	1218	JQ1	BRD2, BRD3, BRD4	11	5	0	NA	1.70322809506458	1.04822814052292	0.654999954541668	0.965289338504925	1.2511436907871	0.620914261654336	0.678552977241161	0.523520966748115	0.268929914869966	NA	NA	NA	0.337382354732135	94.7886666862591
a167	TP53_mut	1028	VX-702	p38	10	4	0.693147180559945	NA	3.22856294239531	2.96997078072703	0.258592161668274	0.298227773716114	0.554277618623933	0.682610719720428	0.867096174330266	0.466539064503928	0.271036015358685	NA	NA	NA	0.4304584614232	94.7886666862591
a168	loss_cnaLIHC7_(CDKN2A)	1043	JNK Inhibitor VIII	JNK	4	10	2.30258509299405	NA	4.58346901602245	4.08912990401995	0.494339112002498	0.211340272866994	0.828381748491966	0.681715150759059	2.3390672553622	0.596752780831327	0.271633522118761	NA	NA	NA	0.107242913610341	94.7886666862591
a169	loss_cnaLIHC7_(CDKN2A)	308	XL-880	MET	4	13	1.63315443905142	NA	0.966417528771523	0.0111198002536405	0.955297728517882	2.77678478135746	0.868150026546049	0.65225827555522	0.344030165726735	1.10038322790653	0.27185386774454	NA	NA	NA	0.543842133577679	94.7886666862591
a170	TP53_mut	265	Tubastatin A	HDAC6	12	5	2.99573227355399	NA	4.98978937773079	4.40191665563669	0.587872722094097	0.850197740853928	1.24208570710008	0.605865374146271	0.691454109844664	0.473294812695829	0.272881287994074	NA	NA	NA	0.372708987000189	94.7886666862591
a171	loss_cnaLIHC7_(CDKN2A)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	10	0.693147180559945	NA	2.79404939614726	2.30732770630944	0.486721689837825	0.696246599611359	0.727159800658575	0.676419455026747	0.699065087153762	0.669346255660736	0.275187529820633	NA	NA	NA	0.288939871284686	94.7886666862591
a172	loss_cnaLIHC7_(CDKN2A)	1069	EHT 1864	Rac GTPases	4	12	2.30258509299405	NA	3.72296621244953	3.14945179027667	0.573514422172852	0.698529327123091	0.922331745668477	0.652326393295267	0.821031272280126	0.621809262086264	0.277521213902724	NA	NA	NA	0.23363124781985	94.7886666862591
a173	loss_cnaLIHC10_(RB1)	201	Epothilone B	Microtubules	3	14	-3.44201937618241	NA	-6.66531479957328	-5.63171114557852	-1.03360365399476	0.783622352792738	1.54766899783006	0.703639249768389	1.3190073640844	0.667845421368488	0.286155224050328	NA	NA	NA	0.142043995491695	94.7886666862591
a174	loss_cnaLIHC10_(RB1)	298	OSI-930	KIT, VEGFR, PDGFR	3	14	2.32630161961136	NA	4.2277083304541	4.53628332496969	-0.30857499451558	0.186587717394856	0.468429158470638	0.699123486262789	1.65377978156288	0.658744206964056	0.289141664284683	NA	NA	NA	0.0959656815134649	94.7886666862591
a175	loss_cnaLIHC10_(RB1)	167	OSU-03012	PDPK1 (PDK1)	3	14	2.77258872223978	NA	1.10772718291471	1.65364447020414	-0.545917287289426	0.65503096820084	0.801985093467576	0.696336955706492	0.833422103368466	0.680707524037662	0.290996013154997	NA	NA	NA	0.287765829067148	94.7886666862591
a176	loss_cnaLIHC7_(CDKN2A)	326	GSK690693	AKT	4	13	2.32630161961136	NA	4.88463714071067	4.31565798387021	0.568979156840459	0.720777375437234	0.951244474931587	0.625366299472935	0.789396526903065	0.598141878176354	0.291325389086516	NA	NA	NA	0.245695702623528	94.7886666862591
a177	TP53_mut	1046	681640	WEE1, CHEK1	10	4	0.693147180559945	NA	2.54678483465792	1.96424143280289	0.582543401855028	0.727196424343433	1.26750892323472	0.652014530272236	0.801081224211177	0.459597081469343	0.292029469094173	NA	NA	NA	0.438426069257886	94.7886666862591
a178	loss_cnaLIHC10_(RB1)	272	AR-42	HDAC	3	14	1.63315443905142	NA	0.0608056934680349	-0.591193413136047	0.651999106604082	0.712472519157929	0.9704694395047	0.693491126294095	0.915121761292182	0.671838885454078	0.292898908214316	NA	NA	NA	0.254283812502053	94.7886666862591
a179	loss_cnaLIHC7_(CDKN2A)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	11	2.30258509299405	NA	4.17350868584769	3.61513033845138	0.558378347396314	0.768837745232191	0.901261042363758	0.639984306474578	0.726262922000119	0.619552295228297	0.292925728844955	NA	NA	NA	0.278528149718855	94.7886666862591
a180	loss_cnaLIHC7_(CDKN2A)	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	13	2.32630161961136	NA	3.3522243357835	1.59595585070089	1.75626848508261	3.24886389424391	2.71082090148151	0.62132844166003	0.540579273940723	0.647873300712258	0.294336340622938	NA	NA	NA	0.37762978032429	94.7886666862591
a181	TP53_mut	1016	Temsirolimus	MTOR	10	4	-1.6094379124341	NA	-2.53823028636814	-1.68812848732716	-0.850101799040982	1.19080149422856	1.6414920288278	0.644992632422036	0.713890436954572	0.517883598647777	0.297017525330828	NA	NA	NA	0.395969938513795	94.7886666862591
a182	loss_cnaLIHC10_(RB1)	1038	NU-7441	PRKDC (DNAPK)	3	11	0.693147180559945	NA	1.72486527495754	2.2431485612958	-0.518283286338266	0.158104692227247	0.799449364005708	0.70741598911153	3.27810186425921	0.648300329793703	0.298773064662	NA	NA	NA	0.0676519868900157	94.7886666862591
a183	TP53_mut	172	Embelin	XIAP	12	5	3.46573590279973	NA	2.82835652335308	2.32852876583744	0.499827757515639	0.986811716604126	0.477925715774941	0.56775585142419	0.506507724934272	1.04582729285698	0.303007538242443	NA	NA	NA	0.181731332948686	94.7886666862591
a184	loss_cnaLIHC10_(RB1)	345	KIN001-270	CDK9	3	14	2.99573227355399	NA	4.19478458711285	4.79217360435059	-0.597389017237736	0.298496907579405	0.959898342326068	0.663589089856404	2.0013239737796	0.622346128643286	0.313451129964725	NA	NA	NA	0.0776296794263528	94.7886666862591
a185	loss_cnaLIHC7_(CDKN2A)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	12	2.30258509299405	NA	1.34174284632088	0.654651361530794	0.687091484790088	1.79024271304517	0.885485323629746	0.601960710723164	0.383797950849558	0.775949037724973	0.314791953801632	NA	NA	NA	0.506826195383653	94.7886666862591
a186	loss_cnaLIHC10_(RB1)	1378	Bleomycin (50 uM)	DNA damage	3	13	3.91202300542815	NA	1.53597336117335	2.27992288506287	-0.74394952388952	0.266190512320185	1.21745088341256	0.657418794838927	2.7948010520926	0.611071488817849	0.32211384433823	NA	NA	NA	0.0647946287591798	94.7886666862591
a187	TP53_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	11	5	2.30258509299405	NA	4.06850888292131	3.28496128187837	0.783547601042939	0.909182496133362	2.23190786007232	0.552164095000869	0.861815536897452	0.351066285064988	0.323323186236031	NA	NA	NA	0.48588075160674	94.7886666862591
a188	loss_cnaLIHC10_(RB1)	166	FTI-277	Farnesyl transferase (FNTA)	3	14	0.0237165266173161	NA	2.36433027440557	1.67444799074739	0.689882283658184	0.308684916372257	1.13509883888711	0.649170242820821	2.23490765848185	0.607772874064933	0.323727757350611	NA	NA	NA	0.0712620148938462	94.7886666862591
a189	TP53_mut	279	BIX02189	MAP2K5 (MEK5)	12	5	2.99573227355399	NA	4.44979374251392	4.88662609486705	-0.436832352353131	0.814396292111573	0.78262156087686	0.541945020259155	0.536387943540986	0.558165496825436	0.324754259345152	NA	NA	NA	0.331056911469175	94.7886666862591
a190	TP53_mut	219	AT-7519	CDK9	12	5	2.32630161961136	NA	1.75070523320172	2.7713413374664	-1.02063610426468	1.77689188299646	2.20765563531482	0.536801485210694	0.574394038281907	0.462316716401801	0.329218814905577	NA	NA	NA	0.392803218118302	94.7886666862591
a191	loss_cnaLIHC10_(RB1)	200	LAQ824	HDAC	3	14	0.0237165266173161	NA	-3.31208464435467	-2.67002120608941	-0.642063438265265	0.628180352550074	1.04713791391671	0.641130361087005	1.02210047744861	0.613160338988866	0.329562028578381	NA	NA	NA	0.221946477442689	94.7886666862591
a192	TP53_mut	333	T0901317	LXR	12	5	2.32630161961136	NA	4.44044209395265	4.05282918100044	0.387612912952203	0.708944553178303	0.759081560218749	0.536373675297348	0.546746443307134	0.510634078425646	0.32959211762228	NA	NA	NA	0.360300492369321	94.7886666862591
a193	TP53_mut	136	Mitomycin C	DNA crosslinker	12	5	2.77258872223978	NA	0.0400057601401127	-0.542401882131332	0.582407642271445	1.22637040414704	0.556755926684871	0.53488594320509	0.47490353673083	1.04607353843418	0.330892650680898	NA	NA	NA	0.198824639296902	94.7886666862591
a194	loss_cnaLIHC7_(CDKN2A)	1067	CCT007093	PPM1D	4	12	1.88706964903238	NA	4.47133054383235	4.2591038479929	0.212226695839449	0.32266823677838	0.376732929386882	0.580138241079019	0.657724162620981	0.563334604662351	0.332031507855193	NA	NA	NA	0.317179597124595	94.7886666862591
a195	TP53_mut	197	Bryostatin 1	PRKC	12	5	-4.8283137373023	NA	-2.68131964402511	-3.07663851124931	0.395318867224196	0.707179210873423	0.837296541446799	0.531267425409538	0.559008043712068	0.472137226962754	0.334071116969409	NA	NA	NA	0.386982168841884	94.7886666862591
a196	loss_cnaLIHC10_(RB1)	219	AT-7519	CDK9	3	14	2.32630161961136	NA	3.03422314703602	1.84017857461746	1.19404457241856	1.19790568760837	1.99055401688712	0.627114534798502	0.996776778648138	0.599855398190015	0.339911533977379	NA	NA	NA	0.231645918272065	94.7886666862591
a197	loss_cnaLIHC10_(RB1)	308	XL-880	MET	3	14	1.63315443905142	NA	-0.527584184673494	0.399498576600279	-0.927082761273772	0.349492040931025	1.58355883112339	0.626523116875979	2.65265772234492	0.58544257595791	0.340353247372418	NA	NA	NA	0.0671274171153558	94.7886666862591
a198	loss_cnaLIHC7_(CDKN2A)	269	NSC-207895	MDM4	4	13	2.99573227355399	NA	3.89244508924364	2.8795477755893	1.01289731365434	2.00693082001202	1.77150551550697	0.556223086430328	0.504699665556119	0.571772035022123	0.346077047793586	NA	NA	NA	0.410120011688543	94.7886666862591
a199	TP53_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	10	4	0.693147180559945	NA	-0.572714618222027	-1.19984291344066	0.627128295218632	0.760254431913163	1.72472164251833	0.57801529800308	0.824892652898423	0.36361130965049	0.34784315000699	NA	NA	NA	0.527615887941799	94.7886666862591
a200	loss_cnaLIHC10_(RB1)	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	-0.149333874268212	0.697481287733626	-0.846815162001838	1.42984387376054	1.36936068825877	0.614712794634381	0.592243095586852	0.618401834712092	0.349258949929177	NA	NA	NA	0.420907039997779	94.7886666862591
a201	loss_cnaLIHC10_(RB1)	326	GSK690693	AKT	3	14	2.32630161961136	NA	4.91253207189924	4.35032186696126	0.562210204937974	0.313557718964553	0.977818085462859	0.61278233926072	1.79300387435696	0.574964007412327	0.350730016168283	NA	NA	NA	0.103698482099059	94.7886666862591
a202	loss_cnaLIHC10_(RB1)	231	FMK	RSK	3	14	2.99573227355399	2.32630161961136	5.34656959449195	4.87090794574398	0.475661648747977	0.0952458759914248	0.838979032264157	0.608402306771832	4.99403930927993	0.566952963609003	0.35408377589397	NA	NA	NA	0.0580853558994676	94.7886666862591
a203	TP53_mut	256	JW-7-24-1	LCK	12	5	2.32630161961136	NA	1.80935307596668	2.59349626899951	-0.784143193032831	1.25228736503768	2.14925991481057	0.50808722723568	0.62616873325176	0.364843352648645	0.354946402427149	NA	NA	NA	0.478464976879505	94.7886666862591
a204	loss_cnaLIHC7_(CDKN2A)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	13	2.77258872223978	NA	-0.412304214563019	-1.54128966336702	1.128985448804	1.51506333643566	2.18930955985918	0.544854274218903	0.745173763797925	0.515681048264648	0.355733877684869	NA	NA	NA	0.281304185670183	94.7886666862591
a205	loss_cnaLIHC7_(CDKN2A)	172	Embelin	XIAP	4	13	3.46573590279973	NA	3.04585003421329	2.56919399789008	0.476656036323214	0.448303252516032	0.966491635669931	0.537137314583117	1.06324465336367	0.493181750086038	0.362394622079583	NA	NA	NA	0.198149583380422	94.7886666862591
a206	loss_cnaLIHC7_(CDKN2A)	207	AS601245	JNK 	4	13	2.07944154167984	NA	2.28214213425524	1.6863011272447	0.595841007010535	1.84998411783061	0.838016634696166	0.533725667915202	0.322078985039747	0.711013340715563	0.365366612640844	NA	NA	NA	0.571722135659667	94.7886666862591
a207	TP53_mut	1149	TW 37	BCL2, BCL2L1	11	4	1.6094379124341	NA	-0.916374570007865	-0.471082735748268	-0.445291834259597	0.667751244153843	1.17939739306455	0.546467599993464	0.666852870972722	0.377558774403045	0.366368901929208	NA	NA	NA	0.517063240100973	94.7886666862591
a208	loss_cnaLIHC10_(RB1)	328	SNX-2112	HSP90	3	14	0.940007258491471	NA	-1.43766446080368	-0.430772070000075	-1.0068923908036	1.46394311466723	1.73722090607603	0.591135544296085	0.687794751527954	0.579599512809188	0.367521806612297	NA	NA	NA	0.365979787444784	94.7886666862591
a209	TP53_mut	1019	Bosutinib	SRC, ABL, TEC	10	4	0.693147180559945	NA	2.06650856383881	1.48146198836268	0.585046575476123	0.887431349924434	1.46783305554283	0.550539903120803	0.659258404073668	0.398578416848476	0.370413019671463	NA	NA	NA	0.498748269277384	94.7886666862591
a210	loss_cnaLIHC10_(RB1)	304	SB52334	ALK5	3	14	2.99573227355399	NA	3.88259778493567	4.50399983131855	-0.621402046382882	0.378859179119253	1.1291203751181	0.586107769610978	1.64019266427034	0.550341717390304	0.371499803932788	NA	NA	NA	0.124095861911058	94.7886666862591
a211	TP53_mut	1059	AZD8055	MTORC1/2	10	4	0.693147180559945	NA	-0.246386166301553	0.131404186911225	-0.377790353212779	0.453205721356564	1.130570189457	0.548969045135549	0.833595727966437	0.334159132034277	0.371733846994257	NA	NA	NA	0.558286223862282	94.7886666862591
a212	loss_cnaLIHC7_(CDKN2A)	223	ZSTK474	PI3K	4	13	1.63315443905142	2.32630161961136	2.07254804335999	1.14245185635828	0.930096187001708	2.62338097227676	1.48326529756193	0.525177566573667	0.354541028097228	0.627059898543117	0.3728866149478	NA	NA	NA	0.539515946606161	94.7886666862591
a213	loss_cnaLIHC7_(CDKN2A)	1052	RO-3306	CDK1	4	10	1.6094379124341	NA	3.52356229642663	3.11332393225708	0.410238364169558	0.492105495652924	0.821761994196891	0.544804046139061	0.833639062748638	0.499217981686394	0.375251853904674	NA	NA	NA	0.279740904737179	94.7886666862591
a214	loss_cnaLIHC10_(RB1)	1262	UNC1215	LMBL3	3	13	0	NA	2.19993484244424	2.43472443068976	-0.234789588245522	0.172094339432667	0.431123417133808	0.580576009346385	1.36430744334496	0.544599478744275	0.380047889867931	NA	NA	NA	0.165706903517662	94.7886666862591
a215	loss_cnaLIHC7_(CDKN2A)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	10	-1.38629436111989	0.693147180559945	-2.15935789031225	-1.68239212433854	-0.476965765973716	1.22580182845616	0.736918563975625	0.539044427281933	0.389105118707837	0.647243520912974	0.380154918508648	NA	NA	NA	0.508208162964185	94.7886666862591
a216	loss_cnaLIHC7_(CDKN2A)	133	Doxorubicin	DNA intercalating	4	13	0.0237165266173161	NA	-1.15103086816431	-1.84486921349401	0.693838345329693	1.89920469350839	1.1746768600508	0.513561626648038	0.365330997601933	0.590663159313182	0.383273761478692	NA	NA	NA	0.530034706652579	94.7886666862591
a217	loss_cnaLIHC10_(RB1)	133	Doxorubicin	DNA intercalating	3	14	0.0237165266173161	NA	-2.31666226689214	-1.54553117481449	-0.77113109207765	1.65171380940626	1.29871066168661	0.570735966651516	0.466867254899835	0.593766660139834	0.383844003096984	NA	NA	NA	0.51118096971068	94.7886666862591
a218	TP53_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	11	4	2.30258509299405	NA	3.88813069300353	3.42275771082926	0.465372982174273	0.991232584601203	0.34152804035442	0.526015182926661	0.469489188918768	1.36262012832484	0.384025401959848	NA	NA	NA	0.199461698398337	94.7886666862591
a219	TP53_mut	1230	IOX2	EGLN1	11	5	-2.30258509299405	NA	0.111428107475609	-0.0282141777038013	0.13964228517941	0.326821225908055	0.153252797503034	0.4846915128236	0.427274222448134	0.911189142740741	0.384038777955068	NA	NA	NA	0.26427135134592	94.7886666862591
a220	loss_cnaLIHC10_(RB1)	1042	BIRB 0796	p38, JNK2	3	10	2.30258509299405	NA	4.30174451203313	3.83403049470114	0.467714017331994	1.01993862854854	0.721812699860351	0.59620130476577	0.45857074557279	0.647971443869695	0.384506440675347	NA	NA	NA	0.519410874920335	94.7886666862591
a221	loss_cnaLIHC10_(RB1)	305	TPCA-1	IKK	3	14	2.99573227355399	NA	2.56192871351561	3.29305579214053	-0.731127078624926	0.300100090997009	1.37301532948861	0.569903482847659	2.43627743062635	0.532497389448114	0.384520344694191	NA	NA	NA	0.0921435258145664	94.7886666862591
a222	TP53_mut	1053	MK-2206	AKT1, AKT2	10	4	1.38629436111989	0.693147180559945	1.06017273580661	1.76525126131407	-0.705078525507452	0.968732931187365	2.06246836438616	0.530377667801112	0.727835818116811	0.341861498427057	0.387616197032452	NA	NA	NA	0.552286658017145	94.7886666862591
a223	loss_cnaLIHC10_(RB1)	293	MP470	PDGFR	3	14	2.99573227355399	NA	2.66476505935737	3.48413276253428	-0.819367703176911	1.2882851872088	1.47639612226448	0.564022092881039	0.636014223645741	0.554978227604778	0.389321484810526	NA	NA	NA	0.397316376430984	94.7886666862591
a224	loss_cnaLIHC7_(CDKN2A)	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.0179030999015525	0.711163385066148	-0.693260285164595	2.26568748561726	1.05543706560315	0.500601024946438	0.305982307606613	0.656846635160023	0.39509185550831	NA	NA	NA	0.590533787117797	94.7886666862591
a225	loss_cnaLIHC10_(RB1)	1059	AZD8055	MTORC1/2	3	11	0.693147180559945	NA	-0.449947443863039	-0.0534911439801376	-0.396456299882901	0.636214669672059	0.700777048542725	0.574211488047988	0.623148630142806	0.565738134128875	0.395315905024194	NA	NA	NA	0.409963917801047	94.7886666862591
a226	loss_cnaLIHC10_(RB1)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	14	1.63315443905142	NA	2.13400238415428	2.76626066176791	-0.632258277613627	0.495115592599511	1.20707437698575	0.555501598412582	1.27699124621399	0.523793968017509	0.396348020005289	NA	NA	NA	0.179366001551311	94.7886666862591
a227	loss_cnaLIHC7_(CDKN2A)	266	Zibotentan, ZD4054	Endothelin A Receptor	4	13	2.99573227355399	NA	5.69259076049723	5.54605057161464	0.146540188882584	0.470413585364693	0.229724272327786	0.498319627354959	0.311513513728515	0.637895975891876	0.39719704905171	NA	NA	NA	0.5848341717663	94.7886666862591
a228	TP53_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	12	5	0.940007258491471	NA	1.88075493001118	1.41186292987784	0.468892000133341	1.02354369677322	0.979770324110236	0.463306408044196	0.458106480076573	0.478573384593128	0.397797017734403	NA	NA	NA	0.401238683296	94.7886666862591
a229	TP53_mut	1114	Cetuximab	EGFR	10	5	4.18661983833127	NA	6.25407541237647	5.69636919454401	0.557706217832459	0.55456388525498	1.92814650597429	0.478786432913769	1.00566631304531	0.28924473119881	0.39790307624191	NA	NA	NA	0.558128714081992	94.7886666862591
a230	loss_cnaLIHC10_(RB1)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	13	-2.30258509299405	NA	0.112031319785158	-0.91043858946584	1.022469909251	0.372266173366311	1.9717919993599	0.558440171948609	2.74660977118886	0.518548563734369	0.397988178137223	NA	NA	NA	0.103782378557345	94.7886666862591
a231	TP53_mut	1248	FK866	NAMPT	11	4	0	NA	-0.880748505342957	-2.48932320806208	1.60857470271912	2.78263345662676	4.2232556177829	0.506850412656438	0.578076389791242	0.380884996860214	0.401091107945468	NA	NA	NA	0.518127132574118	94.7886666862591
a232	loss_cnaLIHC10_(RB1)	203	BMS-345541	IKBKB	3	14	2.77258872223978	NA	4.04887876705808	3.33693638745521	0.711942379602876	1.27773762523272	1.30800111156064	0.545965335386978	0.557189806063045	0.54429799280019	0.404311712787512	NA	NA	NA	0.44779808217794	94.7886666862591
a233	loss_cnaLIHC10_(RB1)	333	T0901317	LXR	3	14	2.32630161961136	NA	4.65369244441858	4.25631240708416	0.397380037334417	0.636620220255693	0.742294475993687	0.545035597505371	0.624202663834355	0.535340151632486	0.405093746279191	NA	NA	NA	0.405890176940737	94.7886666862591
a234	TP53_mut	312	AV-951	VEGFR	12	5	-2.05572501506252	NA	0.317407560761429	0.555341068451226	-0.237933507689797	0.597860944891809	0.208271406513541	0.45480746603008	0.397974662373798	1.1424204199357	0.406304163596764	NA	NA	NA	0.243963810131894	94.7886666862591
a235	TP53_mut	1371	PLX4720 (rescreen)	BRAF	11	5	2.30258509299405	NA	4.29663651393863	3.958262960738	0.338373553200629	0.529097708207874	1.08645940879711	0.461659797633429	0.639529425192082	0.311446106923832	0.406442551008533	NA	NA	NA	0.538107309184441	94.7886666862591
a236	TP53_mut	178	BAY 61-3606	SYK	12	5	2.07944154167984	NA	2.32735073754811	1.64588101872815	0.681469718819956	1.34478064022513	1.86309028194202	0.454130142952997	0.50675158344477	0.365773857244113	0.406987259495883	NA	NA	NA	0.487265320105912	94.7886666862591
a237	TP53_mut	1001	AICAR	AAPK1 (AMPK) agonist	10	4	7.60090245954208	NA	7.89498749475875	8.36713816908971	-0.472150674330961	0.88548144723963	1.05012654931735	0.508026904897368	0.53321351430098	0.449613120092897	0.407320037557645	NA	NA	NA	0.464771107977833	94.7886666862591
a238	loss_cnaLIHC10_(RB1)	205	BMS-708163	g-secretase	3	14	2.32630161961136	0.940007258491471	4.54057301902203	4.7991300745658	-0.258557055543768	0.432110646690403	0.485428044116492	0.540165885356227	0.598358447134068	0.532637243928411	0.409206091454024	NA	NA	NA	0.42192383879975	94.7886666862591
a239	loss_cnaLIHC7_(CDKN2A)	170	Shikonin	unknown	4	13	2.77258872223978	NA	0.300416690166431	-0.312948862055864	0.613365552222295	1.28376677066865	1.26950685764636	0.482064783503985	0.47778581455479	0.483152610423437	0.412411662958925	NA	NA	NA	0.440597390195051	94.7886666862591
a240	loss_cnaLIHC10_(RB1)	341	EX-527	SIRT1	3	14	2.99573227355399	NA	4.95339142489603	5.25775272700654	-0.304361302110511	0.893322074061538	0.498908088917127	0.536262555316351	0.34070724428281	0.610054855536865	0.412522057845511	NA	NA	NA	0.619207346331277	94.7886666862591
a241	TP53_mut	1262	UNC1215	LMBL3	11	5	0	NA	2.33311444945221	2.51739263646504	-0.184278187012832	0.464143413577545	0.195568702203274	0.453928906756531	0.397028551137771	0.942268292097647	0.414153381925516	NA	NA	NA	0.282942586621951	94.7886666862591
a242	loss_cnaLIHC7_(CDKN2A)	177	GSK-650394	SGK3	4	13	2.77258872223978	NA	3.18361923498749	2.49378574875694	0.689833486230548	1.53331088271941	1.41945667511886	0.478072848681567	0.44989799133695	0.485984178539851	0.416205722382099	NA	NA	NA	0.461914742794529	94.7886666862591
a243	loss_cnaLIHC7_(CDKN2A)	158	PF-562271	FAK	3	12	0.940007258491471	NA	1.10539850175604	1.59976112201738	-0.494362620261331	0.56355349412157	0.967036433927782	0.539345953182577	0.877223946649309	0.511214058661052	0.418499892222259	NA	NA	NA	0.296596366177666	94.7886666862591
a244	loss_cnaLIHC7_(CDKN2A)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	13	2.07944154167984	NA	2.77112372855958	1.9830381457266	0.788085582832974	1.05269160136863	1.77661296892229	0.475517600315452	0.748638615344101	0.443588781923074	0.418646196541379	NA	NA	NA	0.303195229847632	94.7886666862591
a245	loss_cnaLIHC10_(RB1)	1036	PLX4720	BRAF	3	11	2.30258509299405	NA	3.55569186668397	4.02759194843347	-0.471900081749499	0.681499745422484	0.897330644867857	0.545482200810551	0.692443518752825	0.525893197171476	0.418691326320419	NA	NA	NA	0.377053385668527	94.7886666862591
a246	loss_cnaLIHC7_(CDKN2A)	1061	SB590885	BRAF	4	10	1.6094379124341	NA	3.98440044049158	3.38664141389187	0.597759026599706	0.985926149773885	1.27223945249476	0.495225158391597	0.606291887822225	0.469847893356513	0.418904712809773	NA	NA	NA	0.37772596944388	94.7886666862591
a247	TP53_mut	152	CP466722	ATM	11	5	2.77258872223978	NA	2.73606316590355	3.42277817748821	-0.686715011584665	1.54748675912991	1.49485284406189	0.448062277303001	0.4437614781084	0.459386363221336	0.420068501289785	NA	NA	NA	0.423826844063455	94.7886666862591
a248	TP53_mut	1033	Vismodegib	SMO	10	4	2.30258509299405	NA	4.5160006837867	4.78366323259303	-0.26766254880633	0.574195651782228	0.436029567273726	0.492968876551794	0.466152169518422	0.613863299408546	0.420968986250723	NA	NA	NA	0.375196827139791	94.7886666862591
a249	loss_cnaLIHC7_(CDKN2A)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	12	0	NA	-1.27792626956245	-2.092311878586	0.814385609023555	1.10030972486267	1.83930190099978	0.476784996730695	0.740142153269798	0.442768861697409	0.422758733050505	NA	NA	NA	0.314406207150622	94.7886666862591
a250	TP53_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	10	4	2.30258509299405	NA	1.18151165403794	0.852620057724955	0.328891596312989	0.420731562711306	1.12415867712111	0.490995394875093	0.781713628028104	0.29256687957545	0.422780042623794	NA	NA	NA	0.605131499031437	94.7886666862591
a251	loss_cnaLIHC10_(RB1)	279	BIX02189	MAP2K5 (MEK5)	3	14	2.99573227355399	NA	4.22814883843201	4.65330063351473	-0.425151795082717	0.619074792311597	0.84152132036202	0.521418281642658	0.686753523746654	0.505218091087483	0.425292305070252	NA	NA	NA	0.373702638738893	94.7886666862591
a252	loss_cnaLIHC7_(CDKN2A)	1262	UNC1215	LMBL3	4	12	0	NA	2.53492129322522	2.34262807944989	0.192293213775327	0.463883741310507	0.3893487930149	0.47307771524529	0.414528893019798	0.493884191309071	0.426291045388982	NA	NA	NA	0.492672677025548	94.7886666862591
a253	TP53_mut	1268	XAV 939	TNKS1 (tankyrase-1)	11	5	1.6094379124341	NA	2.93828063293172	3.27735470904327	-0.339074076111554	0.777856957914499	0.752657296517527	0.439932504021221	0.435908006814827	0.450502609461726	0.428356071329717	NA	NA	NA	0.432282607367277	94.7886666862591
a254	loss_cnaLIHC10_(RB1)	295	NVP-BHG712	EPHB4	3	14	2.32630161961136	NA	2.65619480495091	3.26634525727082	-0.610150452319908	0.785560696778157	1.22742790150098	0.51789879494528	0.776706949345017	0.497096775764813	0.428357034661162	NA	NA	NA	0.331136655295172	94.7886666862591
a255	loss_cnaLIHC7_(CDKN2A)	1114	Cetuximab	EGFR	3	12	4.18661983833127	NA	6.56098591273801	5.94497019652256	0.616015716215448	0.364527433241093	1.26128187924486	0.526965198735103	1.68990221322527	0.488404476709251	0.428994279959238	NA	NA	NA	0.168411482922775	94.7886666862591
a256	loss_cnaLIHC10_(RB1)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	13	2.99573227355399	NA	2.89861137633803	3.60157158349875	-0.702960207160727	0.321868416357185	1.47035009270026	0.514346744669667	2.18399871325254	0.478090361370848	0.435382910446959	NA	NA	NA	0.139214129565154	94.7886666862591
a257	TP53_mut	223	ZSTK474	PI3K	12	5	1.63315443905142	2.32630161961136	1.1378082499924	1.89767346123776	-0.759865211245358	1.57528839291902	2.25602993729945	0.426309915849479	0.482365778013079	0.336815216270997	0.435694304652524	NA	NA	NA	0.519239329521479	94.7886666862591
a258	TP53_mut	1066	AZD6482	PI3Kbeta	11	5	1.6094379124341	NA	1.99708912947755	2.57981500549645	-0.582725876018896	1.26720436661282	1.54118770277458	0.431276189272378	0.459851537267423	0.378101820414101	0.437295671743988	NA	NA	NA	0.485145069116781	94.7886666862591
a259	TP53_mut	1502	Bicalutamide	ANDR (androgen receptor)	10	5	2.30258509299405	NA	4.44783785111369	4.2053933664882	0.242444484625493	0.546789983983795	0.568450030154722	0.437985225484919	0.443395986991376	0.426500961851483	0.438282735788453	NA	NA	NA	0.453622297254683	94.7886666862591
a260	loss_cnaLIHC7_(CDKN2A)	1230	IOX2	EGLN1	4	12	-2.30258509299405	NA	-0.0316536022780265	0.1009377252354	-0.132591327513426	0.470397769631183	0.215856516051431	0.457414201742221	0.281870655163575	0.614256775467617	0.441425189920206	NA	NA	NA	0.619246186691357	94.7886666862591
a261	loss_cnaLIHC10_(RB1)	300	CX-5461	RNA Pol I	3	14	2.32630161961136	NA	4.51296491094405	3.64950584021331	0.863459070730741	0.938713136462908	1.81182694245135	0.50166254551583	0.919832733974805	0.476568181264877	0.44267796374083	NA	NA	NA	0.280495658646093	94.7886666862591
a262	loss_cnaLIHC7_(CDKN2A)	1066	AZD6482	PI3Kbeta	4	12	1.6094379124341	NA	2.64064324007325	2.02537354095353	0.615269699119726	0.656777976014662	1.48619816504724	0.455080686952035	0.936800138843253	0.413989004689809	0.443708780929281	NA	NA	NA	0.276572120053821	94.7886666862591
a263	loss_cnaLIHC10_(RB1)	1243	piperlongumine	Increases ROS levels	3	13	2.30258509299405	NA	1.09867764486229	1.36204068969561	-0.263363044833327	0.589273673503254	0.509673930437406	0.50473062999959	0.446928238398338	0.516728498566342	0.443829009162076	NA	NA	NA	0.53082137846578	94.7886666862591
a264	loss_cnaLIHC10_(RB1)	1061	SB590885	BRAF	3	11	1.6094379124341	NA	3.07053158828292	3.69022010327602	-0.619688514993105	1.44921170869182	1.15753133471273	0.51170233220433	0.427603856135338	0.535353554940174	0.447327291070653	NA	NA	NA	0.547560501328213	94.7886666862591
a265	loss_cnaLIHC7_(CDKN2A)	263	FR-180204	ERK	4	13	2.99573227355399	NA	5.38638778463884	5.09882117268819	0.287566611950647	0.54593192781557	0.673142753224924	0.442616984522142	0.526744447977761	0.427200041258648	0.450892606905792	NA	NA	NA	0.417297079810162	94.7886666862591
a266	loss_cnaLIHC7_(CDKN2A)	271	VNLG/124	HDAC, RAR 	4	13	1.63315443905142	NA	3.88885553157076	3.65995104973738	0.228904481833387	0.656777154409886	0.476159158485649	0.442453882015701	0.348526863786938	0.48073102817424	0.451056248509288	NA	NA	NA	0.552867091526019	94.7886666862591
a267	loss_cnaLIHC7_(CDKN2A)	344	THZ-2-49	CDK9	4	12	2.99573227355399	NA	3.99301315470073	2.97888555595569	1.01412759874505	2.47701065652905	2.22991113096419	0.443797857394844	0.409415920788208	0.454783863205593	0.454855482407519	NA	NA	NA	0.501736039951487	94.7886666862591
a268	loss_cnaLIHC7_(CDKN2A)	295	NVP-BHG712	EPHB4	4	13	2.32630161961136	NA	3.55256443734935	3.0374738667113	0.515090570638058	1.49418565922093	1.08896612783119	0.436079828211603	0.344729965422521	0.473008808514481	0.457480348226413	NA	NA	NA	0.557185568640187	94.7886666862591
a269	loss_cnaLIHC10_(RB1)	303	PIK-93	PI4K, PI3K	3	14	2.99573227355399	NA	2.32719358116699	3.02898517442997	-0.701791593262981	0.19001108512674	1.55284627370672	0.48490205865389	3.6934244799185	0.451938871957858	0.457774056210664	NA	NA	NA	0.123711837848061	94.7886666862591
a270	TP53_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	10	4	0.693147180559945	NA	1.44570709088744	2.05662725138617	-0.610920160498735	1.04354343542131	1.99561541209787	0.453797955729489	0.585428588559025	0.306131209848952	0.457873229534255	NA	NA	NA	0.594791086182543	94.7886666862591
a271	loss_cnaLIHC7_(CDKN2A)	165	DMOG	Prolyl-4-Hydroxylase	4	13	8.29404964010203	NA	4.82218073593926	5.22458503336319	-0.402404297423931	0.729273163699205	0.966479241229852	0.435538817382814	0.551788160396241	0.416361035247761	0.458028204101887	NA	NA	NA	0.404997639256969	94.7886666862591
a272	loss_cnaLIHC7_(CDKN2A)	1033	Vismodegib	SMO	4	10	2.30258509299405	NA	4.76908437617096	4.52183222635553	0.247252149815431	0.601401110039392	0.52521411017209	0.453457529986012	0.411126859741306	0.47076448447742	0.458202736315595	NA	NA	NA	0.504174500780462	94.7886666862591
a273	TP53_mut	1043	JNK Inhibitor VIII	JNK	10	4	2.30258509299405	NA	4.13370499838675	4.47203128010545	-0.338326281718708	0.641970947627926	0.995316052073271	0.453421693258707	0.527011826576918	0.339918442000373	0.458237432334623	NA	NA	NA	0.562848019421162	94.7886666862591
a274	loss_cnaLIHC7_(CDKN2A)	1378	Bleomycin (50 uM)	DNA damage	4	12	3.91202300542815	NA	1.76315745722747	2.26619064670229	-0.503033189474822	1.469525783481	1.04617790487932	0.437386049504711	0.342309876512163	0.480829490977299	0.461267320530337	NA	NA	NA	0.560448055211405	94.7886666862591
a275	TP53_mut	261	TL-1-85	MAP3K7 (TAK1)	12	5	2.32630161961136	NA	2.81198922910847	3.33185902938023	-0.519869800271764	1.10555000313041	1.70720587747945	0.401863578372905	0.470236351860823	0.304515001459173	0.461957041638405	NA	NA	NA	0.555196425696004	94.7886666862591
a276	loss_cnaLIHC7_(CDKN2A)	1241	CHIR-99021	GSK3B	4	12	2.30258509299405	NA	3.10936216039739	3.46093125106637	-0.35156909066898	0.642136749244719	0.852150855287878	0.433108236596336	0.547498786017925	0.412566728634229	0.465576182690597	NA	NA	NA	0.413918358188252	94.7886666862591
a277	TP53_mut	151	QS11	ARFGAP	12	5	2.32630161961136	NA	3.23207202944528	2.61706471462752	0.615007314817763	1.66593426078197	1.17088276652986	0.396916212624625	0.369166616772193	0.525250975074524	0.467388528806	NA	NA	NA	0.405826463805098	94.7886666862591
a278	TP53_mut	1494	SN-38	TOP1	11	5	-2.99573227355399	NA	-3.83366912736639	-4.36698630686185	0.533317179495453	1.14425289891817	1.69495472928801	0.402455369253608	0.466083310778303	0.314649807620219	0.467908682951279	NA	NA	NA	0.546666380472236	94.7886666862591
a279	TP53_mut	1061	SB590885	BRAF	10	4	1.6094379124341	NA	3.71086766714189	3.17383480736654	0.53703285977535	1.16084390293033	1.36043537289644	0.442431134875626	0.462622802617745	0.394750732357081	0.468956450122994	NA	NA	NA	0.518969189698757	94.7886666862591
a280	TP53_mut	306	TG101348	JAK2	12	5	2.32630161961136	NA	2.70666790414857	3.36766422780067	-0.660996323652101	1.6201313565589	1.80660907971036	0.39535786945702	0.407989340479177	0.365876786005125	0.469107417984095	NA	NA	NA	0.502286865098333	94.7886666862591
a281	TP53_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	12	5	1.65632149833295	0.0237165266173161	3.82154377956414	4.12648245739929	-0.304938677835155	0.898416388330421	0.130135168334246	0.394851395907292	0.339417982347628	2.34324573240598	0.469666899414443	NA	NA	NA	0.273544802752936	94.7886666862591
a282	loss_cnaLIHC7_(CDKN2A)	1377	Afatinib (rescreen)	ERBB2, EGFR	4	12	2.30258509299405	NA	4.2866686832492	3.66931078237746	0.617357900871747	1.23228832429553	1.49554566792764	0.42777558129715	0.500984947029076	0.412797759447367	0.470982175940599	NA	NA	NA	0.442017155592331	94.7886666862591
a283	loss_cnaLIHC7_(CDKN2A)	1072	BMS-708163	g-secretase	4	12	1.6094379124341	NA	3.85210285327808	3.58239660392614	0.269706249351934	0.953533517612247	0.508652106554679	0.427448897924756	0.28284925948624	0.5302371618566	0.471314598089379	NA	NA	NA	0.620555541212976	94.7886666862591
a284	TP53_mut	292	Masitinib	KIT	12	5	2.99573227355399	NA	3.75324547697733	4.12178961028	-0.368544133302671	0.89114812661517	1.05330373935594	0.393265961993855	0.413561025710176	0.349893501306682	0.471420892729883	NA	NA	NA	0.515927858641646	94.7886666862591
a285	loss_cnaLIHC7_(CDKN2A)	176	IPA-3	PAK1, PAK2, PAK3	4	13	3.46573590279973	NA	4.34263740271954	3.75780654731634	0.584830855403202	1.609207446363	1.32394335153896	0.422046573706319	0.363427882915275	0.441734047550746	0.47182192023369	NA	NA	NA	0.541969741850158	94.7886666862591
a286	loss_cnaLIHC10_(RB1)	207	AS601245	JNK 	3	14	2.07944154167984	NA	1.39096672040598	1.91982735928458	-0.528860638878604	0.442601011170542	1.1992866703898	0.468801637460304	1.19489252290665	0.440979335413367	0.472571817104655	NA	NA	NA	0.227231074366344	94.7886666862591
a287	TP53_mut	1038	NU-7441	PRKDC (DNAPK)	10	4	0.693147180559945	NA	2.03812603490331	2.36699241252334	-0.328866377620027	0.565151181881484	1.13882767960788	0.437990833580264	0.581908678886904	0.288776242015176	0.4733311516294	NA	NA	NA	0.613920089680614	94.7886666862591
a288	loss_cnaLIHC10_(RB1)	1052	RO-3306	CDK1	3	11	1.6094379124341	NA	2.94295728652624	3.30896514988169	-0.366007863355451	0.968283217625034	0.713727608187338	0.480274008103041	0.377996702507331	0.512811693364371	0.475072443683436	NA	NA	NA	0.589986793292987	94.7886666862591
a289	TP53_mut	1025	SB 216763	GSK3A, GSK3B	7	3	2.30258509299405	NA	4.30057939841197	4.84113900860002	-0.540559610188049	1.20189778143487	0.222485775632034	0.516391631416869	0.449755061152296	2.42963672015631	0.475687359759538	NA	NA	NA	0.2905301558702	94.7886666862591
a290	loss_cnaLIHC7_(CDKN2A)	238	CAL-101	PI3Kdelta	4	13	2.99573227355399	2.32630161961136	5.16828712907881	4.73194875482446	0.436338374254342	1.16265400139525	1.01826055153857	0.41606323717231	0.375295121102848	0.428513481736128	0.478018984997312	NA	NA	NA	0.532563303110482	94.7886666862591
a291	loss_cnaLIHC7_(CDKN2A)	185	OSI-906	IGF1R	4	13	0.940007258491471	NA	1.45145609168569	2.01651636286478	-0.565060271179091	1.64138331307874	1.27764360662891	0.416033970754406	0.344258569388773	0.442267521433474	0.478049417005077	NA	NA	NA	0.560195566700818	94.7886666862591
a292	loss_cnaLIHC10_(RB1)	262	VX-11e	ERK	3	14	1.63315443905142	NA	2.28741771947469	2.95440034869945	-0.666982629224755	1.88098129615745	1.36144235764898	0.462676827326738	0.354592908811637	0.489908827558841	0.478276577727461	NA	NA	NA	0.609153347215597	94.7886666862591
a293	loss_cnaLIHC7_(CDKN2A)	346	THZ-2-102-1	CDK7	4	12	0.916290731874155	2.99573227355399	0.193995655962463	-0.793092443695902	0.987088099658365	3.56772742936382	1.89022167472006	0.419567378007261	0.276671387935703	0.522207587004077	0.479378005589751	NA	NA	NA	0.627803450535293	94.7886666862591
a294	loss_cnaLIHC7_(CDKN2A)	1007	Docetaxel	Microtubules	4	10	-4.38202663467388	NA	-4.36647789303174	-4.9884162623562	0.62193836932446	2.18257923331248	1.11691900301395	0.426491280689127	0.284955689045273	0.556833904379986	0.484777993255889	NA	NA	NA	0.619073225348473	94.7886666862591
a295	loss_cnaLIHC10_(RB1)	173	FH535	unknown 	3	14	3.46573590279973	NA	0.954081844631462	1.52831916249828	-0.574237317866821	0.644070008589631	1.34176213928917	0.451778453950767	0.891575931511346	0.427972515434841	0.488529510380091	NA	NA	NA	0.305304786377475	94.7886666862591
a296	loss_cnaLIHC10_(RB1)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	14	2.32630161961136	NA	4.95035679196347	4.72186668770687	0.228490104256606	0.263994158272503	0.536246370289904	0.449394457607669	0.865511970991235	0.426091656588893	0.490789627301906	NA	NA	NA	0.314542298799337	94.7886666862591
a297	loss_cnaLIHC10_(RB1)	1149	TW 37	BCL2, BCL2L1	3	12	1.6094379124341	NA	-1.0974998700694	-0.722662633572615	-0.374837236496788	0.399824098895646	0.881968955789107	0.453627004919793	0.937505361813171	0.425000487870253	0.494600653356984	NA	NA	NA	0.308185447099007	94.7886666862591
a298	TP53_mut	273	CUDC-101	HDAC, EGFR	12	5	1.63315443905142	NA	-0.39137877908784	-1.07918235133945	0.687803572251611	1.84186375540569	1.87161768987763	0.371816880442114	0.373428040067012	0.367491489299068	0.495538696948473	NA	NA	NA	0.508992971455405	94.7886666862591
a299	TP53_mut	1050	ZM-447439	AURKB	8	3	1.38629436111989	0.693147180559945	2.61734093740337	2.20494906051106	0.412391876892304	0.878069775624836	0.783263970558379	0.48069492371083	0.469657296424814	0.526504336205219	0.495667627693103	NA	NA	NA	0.493290909749373	94.7886666862591
a300	TP53_mut	328	SNX-2112	HSP90	12	5	0.940007258491471	NA	-0.420001103971273	-1.06075782295136	0.640756718980088	1.82246626910455	1.41773685932511	0.371699948763472	0.351587697310259	0.451957438198446	0.495672143457853	NA	NA	NA	0.455226593741509	94.7886666862591
a301	loss_cnaLIHC7_(CDKN2A)	1219	PFI-1	BRD2, BRD3, BRD4	4	12	2.30258509299405	NA	2.86663337579323	2.59358334828405	0.273050027509178	0.740306677242721	0.662050528478356	0.401793063939128	0.368833668400986	0.412430797595994	0.497866264271596	NA	NA	NA	0.542757615898053	94.7886666862591
a302	loss_cnaLIHC7_(CDKN2A)	298	OSI-930	KIT, VEGFR, PDGFR	4	13	2.32630161961136	NA	4.61869544035785	4.43971613688512	0.178979303472733	0.513452060734503	0.434791900626028	0.396303943883097	0.348580358635039	0.411643600570831	0.498829295373656	NA	NA	NA	0.559227660254955	94.7886666862591
a303	loss_cnaLIHC7_(CDKN2A)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	13	0.246860077931526	2.32630161961136	1.65249635814472	1.07616317464852	0.576333183496201	1.51463161930513	1.44421257353551	0.395136207949241	0.380510466142656	0.399063956412805	0.500075579501852	NA	NA	NA	0.532025228983754	94.7886666862591
a304	loss_cnaLIHC10_(RB1)	1375	Temozolomide	DNA akylating agent	3	13	3.40119738166216	NA	5.5396289268902	5.72363511993642	-0.184006193046225	0.329456175704255	0.428120010324438	0.442895157653355	0.558514930408842	0.429800496610242	0.500576918290327	NA	NA	NA	0.460611162156959	94.7886666862591
a305	TP53_mut	135	Gemcitabine	DNA replication	12	5	0.0237165266173161	NA	-2.22687664153564	-3.04126459477927	0.814387953243624	2.30877357275412	1.94513728484592	0.367231516755375	0.352736172509176	0.418678907441813	0.500787493530214	NA	NA	NA	0.476439846259711	94.7886666862591
a306	loss_cnaLIHC10_(RB1)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	11	1.6094379124341	NA	1.30980437286034	0.831091641843433	0.478712731016903	1.09128646656876	1.06096305976114	0.449041480191273	0.438668255936573	0.451205842288872	0.503676950043753	NA	NA	NA	0.544914897824219	94.7886666862591
a307	loss_cnaLIHC10_(RB1)	134	Etoposide	TOP2	3	14	2.77258872223978	NA	0.702499765042909	1.51133093221784	-0.808831167174935	1.92615991768709	1.84489270266309	0.435808165002981	0.41991901074661	0.438416372945372	0.503787558819203	NA	NA	NA	0.556003173860788	94.7886666862591
a308	TP53_mut	222	BX-912	PDPK1 (PDK1)	12	5	2.32630161961136	NA	2.88704556821683	3.46000293879774	-0.572957370580909	1.72697281293854	1.06819321502188	0.362995273015529	0.331769768631152	0.536379900680397	0.50566541071487	NA	NA	NA	0.422589919014691	94.7886666862591
a309	loss_cnaLIHC7_(CDKN2A)	290	KIN001-260	IKK	4	13	2.99573227355399	NA	4.44292253620324	4.83943463146448	-0.396512095261235	1.69638662358275	0.761408411271603	0.388935580568053	0.233739225332847	0.520761380346499	0.506723721024209	NA	NA	NA	0.677659594546131	94.7886666862591
a310	loss_cnaLIHC7_(CDKN2A)	1001	AICAR	AAPK1 (AMPK) agonist	4	10	7.60090245954208	NA	7.75995076152696	8.13786245778385	-0.377911696256882	0.482618820876815	1.04855000165588	0.402210587799668	0.783043843110588	0.360413614667952	0.509496279421409	NA	NA	NA	0.375808086725615	94.7886666862591
a311	loss_cnaLIHC10_(RB1)	1069	EHT 1864	Rac GTPases	3	13	2.30258509299405	NA	2.9750456993525	3.3661653257739	-0.391119626421403	0.425622985952811	0.96060115864942	0.432761496447627	0.91893445450516	0.407161310289598	0.510270685130884	NA	NA	NA	0.31320143340663	94.7886666862591
a312	TP53_mut	1133	JNJ-26854165	MDM2	11	4	2.30258509299405	NA	2.45659999215785	2.68794665281925	-0.231346660661394	0.56880822195235	0.642111266199372	0.394427411126919	0.406721724006258	0.360290611361992	0.511174166427739	NA	NA	NA	0.553887510628001	94.7886666862591
a313	TP53_mut	1026	17-AAG	HSP90	10	4	0	NA	0.551958645196105	-0.0500866596752641	0.602045304871369	1.71702807863961	0.476545576865116	0.399775320093513	0.350632183807014	1.263353043442	0.512016035435551	NA	NA	NA	0.330799212786463	94.7886666862591
a314	loss_cnaLIHC10_(RB1)	1026	17-AAG	HSP90	3	11	0	NA	0.899865096614854	0.238149502128676	0.661715594486178	1.32712648556686	1.53934745873987	0.439370014176838	0.498607782816976	0.429867597941706	0.512739277938561	NA	NA	NA	0.504900386787432	94.7886666862591
a315	loss_cnaLIHC10_(RB1)	1058	GDC0941	PI3K (class 1)	3	11	1.38629436111989	0.693147180559945	0.653018560271077	1.27417289975183	-0.621154339480758	0.534611130310983	1.53479499610676	0.438059708870952	1.16188067225505	0.404714858372883	0.513974402818591	NA	NA	NA	0.28904867345772	94.7886666862591
a316	loss_cnaLIHC10_(RB1)	172	Embelin	XIAP	3	14	3.46573590279973	NA	2.36699785120753	2.74870918255726	-0.381711331349727	0.600869904942953	0.937472270623537	0.424172673721693	0.635264519340451	0.407170796738171	0.515076791756647	NA	NA	NA	0.418064783939471	94.7886666862591
a317	TP53_mut	304	SB52334	ALK5	12	5	2.99573227355399	NA	4.50590962577182	4.12657509680098	0.379334528970839	1.03936300274279	1.16447797955341	0.353147619416901	0.364968281504929	0.32575500407171	0.517110592248339	NA	NA	NA	0.548492546301679	94.7886666862591
a318	loss_cnaLIHC10_(RB1)	152	CP466722	ATM	3	13	2.77258872223978	NA	3.48009386789647	2.82848493143774	0.651608936458727	1.24710334275325	1.59062510266895	0.421417789207715	0.522497947138974	0.409655886459591	0.521250162821906	NA	NA	NA	0.486664552532902	94.7886666862591
a319	TP53_mut	228	KIN001-102	AKT1	11	5	2.32630161961136	NA	3.12315804469779	3.74960124758566	-0.626443202887875	1.82249560117827	1.62909890235824	0.354043188163539	0.343728238621192	0.384533561456001	0.522201657918463	NA	NA	NA	0.5102586183263	94.7886666862591
a320	loss_cnaLIHC7_(CDKN2A)	163	JQ1	BRD4	4	13	0.940007258491471	NA	0.543292379654334	-0.130499807762536	0.67379218741687	2.13924145149169	1.70837255986759	0.373746894855827	0.314967806437668	0.39440588267766	0.523223038962685	NA	NA	NA	0.593765231477005	94.7886666862591
a321	TP53_mut	1013	Nilotinib	ABL	9	3	0.693147180559945	NA	3.10770378889894	3.28795566409547	-0.180251875196531	0.439524542015725	0.25107545797792	0.440882030003024	0.410106508205136	0.71791913334828	0.523349462171812	NA	NA	NA	0.413030492036672	94.7886666862591
a322	loss_cnaLIHC7_(CDKN2A)	1032	Afatinib	ERBB2, EGFR	4	10	-0.693147180559945	NA	1.52755819167369	1.08439890439748	0.443159287276213	0.68679320034602	1.26044366123212	0.387269910169723	0.645258699493444	0.351589920998939	0.525070248136271	NA	NA	NA	0.418735774055688	94.7886666862591
a323	TP53_mut	1264	SGC0946	Q8TEK3 (DOT1L)	11	5	-0.693147180559945	NA	1.6744118474566	1.7953032523642	-0.120891404907594	0.386496669591628	0.205749672834889	0.350749082611604	0.312787701470565	0.587565478194499	0.526023011103105	NA	NA	NA	0.4298035440963	94.7886666862591
a324	loss_cnaLIHC7_(CDKN2A)	221	TAK-715	p38a	4	13	2.99573227355399	2.32630161961136	4.60037756501225	4.20705124214675	0.3933263228655	1.57689746564152	0.889505747142619	0.369961582057646	0.249430499722114	0.442185251898587	0.527381894212004	NA	NA	NA	0.661385309609125	94.7886666862591
a325	loss_cnaLIHC10_(RB1)	282	EKB-569	EGFR	3	14	0.916290731874155	2.99573227355399	1.48612229244756	2.18450453750381	-0.698382245056258	1.62752036723778	1.71320649620196	0.410322885764402	0.429108144582883	0.407646274167484	0.528701334731249	NA	NA	NA	0.551331265384955	94.7886666862591
a326	loss_cnaLIHC10_(RB1)	258	STF-62247	stimulates autophagy	3	14	2.32630161961136	NA	4.37889905815404	4.62316486800985	-0.24426580985581	0.936863473122043	0.53154683999184	0.406040613465935	0.260727221055816	0.45953769541657	0.53295460074603	NA	NA	NA	0.700152993757925	94.7886666862591
a327	loss_cnaLIHC10_(RB1)	1066	AZD6482	PI3Kbeta	3	13	1.6094379124341	NA	2.63222888297794	2.07464375406165	0.557585128916293	0.728505026337694	1.44069185977071	0.409403266408889	0.765382679264903	0.387025945301748	0.53302474501677	NA	NA	NA	0.371524507448101	94.7886666862591
a328	loss_cnaLIHC7_(CDKN2A)	1133	JNJ-26854165	MDM2	4	11	2.30258509299405	NA	2.67813241472452	2.46016880601048	0.217963608714039	0.371954158013046	0.638352366096114	0.370879747190955	0.585995892285182	0.341447169761444	0.536315733542243	NA	NA	NA	0.435214707437839	94.7886666862591
a329	TP53_mut	1241	CHIR-99021	GSK3B	11	5	2.30258509299405	NA	3.28664790330964	3.563099343596	-0.276451440286355	0.742387174998793	0.977432054934336	0.33859069102243	0.372381756577091	0.282834432215267	0.540263788424359	NA	NA	NA	0.593238033469093	94.7886666862591
a330	TP53_mut	290	KIN001-260	IKK	12	5	2.99573227355399	NA	4.6461953486808	4.98599923393632	-0.339803885255524	1.07724080072282	0.851257186937058	0.332529237320938	0.315439115402534	0.399178873870288	0.541545804966921	NA	NA	NA	0.50581481933916	94.7886666862591
a331	loss_cnaLIHC10_(RB1)	153	Midostaurin	KIT	3	14	-0.669430653942629	NA	-0.951019231332921	-0.427872499754387	-0.523146731578534	1.20913126082779	1.33549003667074	0.396521059544685	0.432663308382564	0.391726420425188	0.542477641853731	NA	NA	NA	0.550267412641528	94.7886666862591
a332	loss_cnaLIHC7_(CDKN2A)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	12	1.6094379124341	NA	1.37838145264498	1.06291297172732	0.31546848091766	0.893371783061527	0.771486635427587	0.398590112605119	0.353121160639942	0.408909845525472	0.547573925999465	NA	NA	NA	0.616263518925178	94.7886666862591
a333	loss_cnaLIHC7_(CDKN2A)	194	AUY922	HSP90	4	13	-1.36257783450257	NA	-2.26156320231659	-2.96608710420105	0.704523901884468	2.93133478007954	1.69688866512799	0.351293293979913	0.240342354163093	0.4151856962468	0.548161501231275	NA	NA	NA	0.6731552536304	94.7886666862591
a334	loss_cnaLIHC10_(RB1)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	11	-1.38629436111989	0.693147180559945	-2.84015466668587	-2.37690433340713	-0.463250333278733	0.39229472160155	1.26389246740748	0.397696768051454	1.18087322558791	0.3665266984532	0.552864340152514	NA	NA	NA	0.317909170904455	94.7886666862591
a335	TP53_mut	258	STF-62247	stimulates autophagy	12	5	2.32630161961136	NA	4.52294208343082	4.71714006508604	-0.194197981655216	0.665735607453035	0.376674725808246	0.322388854894602	0.291704363535814	0.515558831929903	0.553793006441099	NA	NA	NA	0.460763280061168	94.7886666862591
a336	loss_cnaLIHC7_(CDKN2A)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	10	-1.6094379124341	NA	0.121736086313571	0.428226386125534	-0.306490299811964	0.949093439079509	0.816280576852928	0.359971962239957	0.322929531689965	0.375471753834448	0.55422302079614	NA	NA	NA	0.595500413263402	94.7886666862591
a337	loss_cnaLIHC10_(RB1)	211	TL-2-105	CRAF	3	14	2.32630161961136	1.63315443905142	4.5603164949069	4.22503139770445	0.335285097202452	0.275559600900738	0.934716425911693	0.38275787255002	1.21674257077774	0.358702476930825	0.556409593155905	NA	NA	NA	0.27900508508737	94.7886666862591
a338	TP53_mut	295	NVP-BHG712	EPHB4	12	5	2.32630161961136	NA	3.27018106310886	2.89104905186758	0.379132011241278	1.06644297029766	1.47664084718714	0.318668250501179	0.35551081661259	0.256753029664247	0.558323881295257	NA	NA	NA	0.621986127006879	94.7886666862591
a339	TP53_mut	1022	AZD7762	CHEK1, CHEK2	10	4	0.693147180559945	NA	0.0629321492322415	0.649196597255735	-0.586264448023493	1.70584006982517	1.46320961926571	0.355627821578395	0.343680781331147	0.400670170769997	0.558943777724805	NA	NA	NA	0.541004363736368	94.7886666862591
a340	TP53_mut	1049	PD-173074	FGFR1, FGFR3	10	4	0.693147180559945	NA	2.57500019558173	2.02920296961856	0.545797225963164	1.17067993975115	2.30596948524911	0.355491480056458	0.46622241265976	0.236688832811767	0.559092295695131	NA	NA	NA	0.677739235375154	94.7886666862591
a341	loss_cnaLIHC10_(RB1)	294	MPS-1-IN-1	MPS1	3	14	2.99573227355399	NA	3.85936923462088	4.25199854858717	-0.39262931396629	0.961759696223848	1.04392547600878	0.379958610103414	0.408240556874933	0.37610856616645	0.559266576234071	NA	NA	NA	0.570941919788446	94.7886666862591
a342	TP53_mut	1199	Tamoxifen	ER	11	5	1.6094379124341	NA	3.71824245364363	3.50854788738768	0.209694566255949	0.593762722032823	0.783555064354336	0.320812031990129	0.353162228740181	0.267619438371879	0.561467104828883	NA	NA	NA	0.61268114939231	94.7886666862591
a343	loss_cnaLIHC7_(CDKN2A)	260	NG-25	MAP3K7 (TAK1)	4	13	2.32630161961136	NA	2.81259442666465	2.43429867208122	0.378295754583425	1.8876336964951	0.860313623042425	0.331183615881624	0.200407396459299	0.439718428781372	0.571035403659223	NA	NA	NA	0.720708019795976	94.7886666862591
a344	loss_cnaLIHC10_(RB1)	208	SB-715992	KIF11	3	14	-2.05572501506252	NA	-0.320785351908295	-0.925886123898614	0.605100771990319	1.05567871825826	1.71827954150777	0.367748023108504	0.573186483278418	0.352155023308577	0.57182009925273	NA	NA	NA	0.466078789207929	94.7886666862591
a345	loss_cnaLIHC10_(RB1)	281	CH5424802	ALK	3	14	1.63315443905142	NA	3.86164663143074	4.03528868501408	-0.173642053583341	0.651606687468063	0.442257762352183	0.36515769398576	0.266482921251253	0.392626355860466	0.574502069110994	NA	NA	NA	0.696096658577686	94.7886666862591
a346	loss_cnaLIHC10_(RB1)	1529	MLN4924	NEDD8-activating enzyme	3	11	0	NA	0.514114234049489	0.0172207995245592	0.49689343452493	2.0970108236003	1.11028695213403	0.374527303920598	0.236953204500789	0.447536047838693	0.57590625976796	NA	NA	NA	0.725955010713879	94.7886666862591
a347	loss_cnaLIHC10_(RB1)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	14	0.940007258491471	NA	2.04903184630186	1.67723416218698	0.371797684114876	0.971496274805067	1.03443427703373	0.362282134103102	0.382706237540105	0.359421272447599	0.577487030472116	NA	NA	NA	0.593209191825885	94.7886666862591
a348	loss_cnaLIHC10_(RB1)	1241	CHIR-99021	GSK3B	3	13	2.30258509299405	NA	3.61360081052032	3.31752470944808	0.296076101072237	0.629394961456911	0.846051776863235	0.36167752604298	0.470413840598416	0.34995033302802	0.58123436258377	NA	NA	NA	0.532156767288589	94.7886666862591
a349	loss_cnaLIHC10_(RB1)	1114	Cetuximab	EGFR	3	12	4.18661983833127	NA	6.41195654925684	5.98222753739285	0.429729011863984	0.521036760725185	1.26812293886068	0.362863936885804	0.824757568479204	0.338870151067582	0.583579555937336	NA	NA	NA	0.388592440751104	94.7886666862591
a350	loss_cnaLIHC7_(CDKN2A)	1023	GW 441756	NTRK1	4	10	0.693147180559945	NA	2.01933208301944	2.34421795468542	-0.324885871665981	0.966142966659373	0.985483594048474	0.331284905749597	0.336271010479264	0.329671517240906	0.585799081642961	NA	NA	NA	0.59354366682419	94.7886666862591
a351	loss_cnaLIHC7_(CDKN2A)	226	GSK1070916	AURKB	4	13	0.940007258491471	2.32630161961136	2.55523032845183	1.95989309831436	0.595337230137472	1.64713450852838	1.92451964135114	0.317965452828806	0.361438138206074	0.309343286161272	0.586339247724117	NA	NA	NA	0.567098425031005	94.7886666862591
a352	TP53_mut	272	AR-42	HDAC	12	5	1.63315443905142	NA	-0.39203881248497	-0.677964990736183	0.285926178251213	0.906106777845589	1.11682174058291	0.295745394158033	0.315554618111397	0.256017740218754	0.586670280152749	NA	NA	NA	0.629261303216685	94.7886666862591
a353	TP53_mut	260	NG-25	MAP3K7 (TAK1)	12	5	2.32630161961136	NA	2.42417727012599	2.76122664044052	-0.337049370314533	1.15623237161988	1.10706175564826	0.294797002424968	0.29150660246809	0.304453991473284	0.587858765518309	NA	NA	NA	0.588146868443596	94.7886666862591
a354	loss_cnaLIHC7_(CDKN2A)	341	EX-527	SIRT1	4	13	2.99573227355399	NA	5.34308548334286	5.16125927072371	0.181826212619153	0.631002835323074	0.560142350506046	0.316212098706371	0.288154351202017	0.324607151119509	0.58838493102498	NA	NA	NA	0.629197347712332	94.7886666862591
a355	TP53_mut	277	ABT-869	VEGFR and PDGFR family	12	5	0.0237165266173161	NA	2.36124482373769	2.25107430347882	0.110170520258878	0.37875549111173	0.365617659694096	0.293555525945423	0.290875044307618	0.301327130508562	0.589416385809714	NA	NA	NA	0.591110300134993	94.7886666862591
a356	loss_cnaLIHC7_(CDKN2A)	225	Genentech Cpd 10	AURKA, AURKB	4	13	2.32630161961136	NA	3.17112507300488	2.56725885993201	0.603866213072863	2.37360050642144	1.78440825171722	0.315040265748545	0.254409371517738	0.338412587193392	0.589754163100689	NA	NA	NA	0.662499178389512	94.7886666862591
a357	loss_cnaLIHC7_(CDKN2A)	235	QL-XII-47	BTK, BMX	4	13	2.32630161961136	NA	2.61336008421482	1.86458724545576	0.748772838759059	2.5416227855471	2.34546157358211	0.313821355055403	0.294604235930266	0.319243276970637	0.591180119541902	NA	NA	NA	0.623732823871843	94.7886666862591
a358	TP53_mut	203	BMS-345541	IKBKB	12	5	2.77258872223978	NA	3.57607495364321	3.19016925636572	0.385905697277487	1.2076140103748	1.59620526225277	0.29181105659738	0.31956046713777	0.241764456240951	0.591608627419448	NA	NA	NA	0.64432840635495	94.7886666862591
a359	TP53_mut	326	GSK690693	AKT	12	5	2.32630161961136	NA	4.36945128741449	4.64173738083629	-0.272286093421794	1.03096787636413	0.602846566053649	0.290858595670501	0.264107252674111	0.451667320930816	0.592807308006187	NA	NA	NA	0.50982489470088	94.7886666862591
a360	loss_cnaLIHC10_(RB1)	1053	MK-2206	AKT1, AKT2	3	11	1.38629436111989	0.693147180559945	1.64213071376149	1.15784911473072	0.484281599030764	0.946381678849788	1.42420547481997	0.357058459892841	0.511719119097223	0.340036327336812	0.593612032645291	NA	NA	NA	0.517784042064072	94.7886666862591
a361	loss_cnaLIHC10_(RB1)	1527	GDC0941 (rescreen)	PI3K	3	12	1.38629436111989	NA	0.526042123335461	0.832072068313778	-0.306029944978317	0.91271383077265	0.867387759993278	0.349942906890953	0.335296710382103	0.352817919612664	0.596900239979369	NA	NA	NA	0.636444404895718	94.7886666862591
a362	loss_cnaLIHC10_(RB1)	344	THZ-2-49	CDK9	3	13	2.99573227355399	NA	2.58373220387454	3.38211405220366	-0.79838184832912	2.88451324173891	2.19839185608592	0.345780602893195	0.276782174814293	0.363166305460476	0.597783401945659	NA	NA	NA	0.687860585625349	94.7886666862591
a363	loss_cnaLIHC10_(RB1)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	14	-0.669430653942629	NA	-5.29251978414944	-4.56388895603293	-0.728630828116519	0.696793662374279	2.27729903605375	0.341237032821469	1.04569095194373	0.319953952722493	0.599574710907432	NA	NA	NA	0.337682973880866	94.7886666862591
a364	loss_cnaLIHC7_(CDKN2A)	166	FTI-277	Farnesyl transferase (FNTA)	4	13	0.0237165266173161	NA	2.05132957142897	1.71768803138187	0.333641540047098	0.965031413576553	1.11735943963827	0.306486697615175	0.345731273980576	0.298598220242457	0.599797353126847	NA	NA	NA	0.582804689579649	94.7886666862591
a365	loss_cnaLIHC7_(CDKN2A)	1527	GDC0941 (rescreen)	PI3K	3	12	1.38629436111989	NA	1.01301928121187	0.710327778844675	0.302691502367197	1.01287953255443	0.847193076778907	0.346040555877525	0.298842550015621	0.357287507020304	0.600953561835476	NA	NA	NA	0.668395346544138	94.7886666862591
a366	loss_cnaLIHC10_(RB1)	136	Mitomycin C	DNA crosslinker	3	14	2.77258872223978	NA	0.180194813350511	-0.198037480644774	0.378232293995285	0.931904637247793	1.13985742717729	0.339412111853657	0.405870170484744	0.331824213254396	0.601509784321782	NA	NA	NA	0.578866315178363	94.7886666862591
a367	loss_cnaLIHC10_(RB1)	256	JW-7-24-1	LCK	3	14	2.32630161961136	NA	2.46907480816788	1.948035273721	0.521039534446879	0.799881886238729	1.66288805000844	0.330739636269264	0.651395591537838	0.313334102343351	0.610747942625769	NA	NA	NA	0.444764818148925	94.7886666862591
a368	TP53_mut	341	EX-527	SIRT1	12	5	2.99573227355399	NA	5.25066967474181	5.09213527117559	0.158534403566216	0.557711096966358	0.622609554557035	0.275360934711522	0.284259008702815	0.25462892820366	0.612481674814599	NA	NA	NA	0.637500779268202	94.7886666862591
a369	loss_cnaLIHC10_(RB1)	306	TG101348	JAK2	3	14	2.32630161961136	NA	3.35809507352027	2.80314648344467	0.554948590075602	0.930500735851191	1.77542971974992	0.328878525732609	0.59639779818976	0.312571420824119	0.612739463282325	NA	NA	NA	0.469191588015667	94.7886666862591
a370	loss_cnaLIHC10_(RB1)	1218	JQ1	BRD2, BRD3, BRD4	3	13	0	NA	1.20491187391143	1.56630108666083	-0.361389212749397	1.08072439185808	1.09543664232746	0.330534778496509	0.334395351369894	0.329904258069694	0.613874877667667	NA	NA	NA	0.638186143973698	94.7886666862591
a371	TP53_mut	224	AS605240	PI3Kgamma	12	5	2.99573227355399	2.32630161961136	3.7156230890071	4.21956918796796	-0.503946098960868	1.937622593876	1.53038422846421	0.27420115092882	0.260084755696815	0.329293839800345	0.613966763828935	NA	NA	NA	0.581713893296135	94.7886666862591
a372	loss_cnaLIHC7_(CDKN2A)	292	Masitinib	KIT	4	13	2.99573227355399	NA	4.07059077267103	3.79734851418798	0.273242258483048	0.756567240207931	0.987725233948441	0.288832543449454	0.361160573656284	0.276637924284631	0.620791860452913	NA	NA	NA	0.578193557580085	94.7886666862591
a373	TP53_mut	345	KIN001-270	CDK9	12	5	2.99573227355399	NA	4.61388720357956	4.86162755585841	-0.247740352278846	0.916328805082343	0.946743030825047	0.267961504540645	0.270361851449801	0.261676446736504	0.621986428423676	NA	NA	NA	0.634266939858341	94.7886666862591
a374	TP53_mut	291	KIN001-266	MAP3K8 (COT)	12	5	2.99573227355399	NA	3.40440934129583	3.73428366936532	-0.329874328069492	1.14770407664552	1.44711256947005	0.267176927336581	0.287421065048091	0.227953467497208	0.622998367294819	NA	NA	NA	0.665442305002495	94.7886666862591
a375	loss_cnaLIHC7_(CDKN2A)	1030	KU-55933	ATM	4	10	2.30258509299405	NA	3.76071686610948	3.5356819048042	0.225034961305279	0.309573578740456	0.852998800324524	0.298153934409284	0.726919145428579	0.263816269401158	0.623405654489027	NA	NA	NA	0.483185201531507	94.7886666862591
a376	loss_cnaLIHC10_(RB1)	1072	BMS-708163	g-secretase	3	13	1.6094379124341	NA	3.48325836465172	3.68826119740545	-0.205002832753733	0.92799754413739	0.574971148451757	0.321579479184758	0.220908809564029	0.356544555854239	0.62342484322182	NA	NA	NA	0.744069718653656	94.7886666862591
a377	loss_cnaLIHC7_(CDKN2A)	279	BIX02189	MAP2K5 (MEK5)	4	13	2.99573227355399	NA	4.75924885433089	4.52258922824451	0.236659626086375	1.13534306043312	0.729200603513287	0.286321651151143	0.208447679238108	0.324546667880073	0.623806308013713	NA	NA	NA	0.715583982357851	94.7886666862591
a378	loss_cnaLIHC10_(RB1)	163	JQ1	BRD4	3	14	0.940007258491471	NA	-0.445501700646867	0.129512651403213	-0.57501435205008	0.922963651705301	1.91390848915428	0.317101409328446	0.623008664520713	0.300439835712399	0.625414540995069	NA	NA	NA	0.463557298762794	94.7886666862591
a379	loss_cnaLIHC7_(CDKN2A)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	10	-1.38629436111989	0.693147180559945	-2.72384152368954	-2.37710455727779	-0.346736966411751	0.280748635862515	1.34196841974016	0.296197995204442	1.23504417161817	0.25837937861376	0.625662395679688	NA	NA	NA	0.45472328431617	94.7886666862591
a380	loss_cnaLIHC10_(RB1)	206	Ruxolitinib	JAK1, JAK2, TYK2	3	14	1.65632149833295	0.0237165266173161	3.70773965495973	3.95483704834907	-0.247097393389338	0.374814101471739	0.824751058696547	0.316830463781049	0.659253193567396	0.299602396121631	0.625707608517537	NA	NA	NA	0.449593090182839	94.7886666862591
a381	loss_cnaLIHC10_(RB1)	254	AC220	FLT3	3	14	0.0237165266173161	NA	2.6446183879344	2.44078118191047	0.203837206023928	0.265487112004165	0.689857326477504	0.313838261305799	0.76778569206301	0.29547733741518	0.628948445235237	NA	NA	NA	0.417147263464287	94.7886666862591
a382	loss_cnaLIHC7_(CDKN2A)	1494	SN-38	TOP1	4	12	-2.99573227355399	NA	-3.71398800184679	-4.09577832732937	0.381790325482577	2.19160227532572	0.986992608177654	0.284993780566523	0.174206027152365	0.386821869099405	0.629225550371826	NA	NA	NA	0.755647334327805	94.7886666862591
a383	loss_cnaLIHC10_(RB1)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	10	1.38629436111989	0.693147180559945	3.13212770358979	2.59278784373562	0.539339859854163	1.30705873999664	1.73339519777521	0.324117833397155	0.412636282785233	0.311146506316851	0.632137077835819	NA	NA	NA	0.591438351768684	94.7886666862591
a384	loss_cnaLIHC7_(CDKN2A)	206	Ruxolitinib	JAK1, JAK2, TYK2	4	13	1.65632149833295	0.0237165266173161	4.07778617663301	3.85998407194108	0.217802104691928	0.654847081211828	0.808446370970505	0.279179929303064	0.332599947286738	0.269408228563715	0.6324182105494	NA	NA	NA	0.602498351369538	94.7886666862591
a385	loss_cnaLIHC7_(CDKN2A)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	12	2.99573227355399	NA	3.76173852069638	3.37244255264269	0.389295968053686	1.64154085723132	1.30788608596114	0.280844683527867	0.23715277407733	0.297652809546943	0.634183595960274	NA	NA	NA	0.687038431384187	94.7886666862591
a386	loss_cnaLIHC7_(CDKN2A)	291	KIN001-266	MAP3K8 (COT)	4	13	2.99573227355399	NA	3.75990575644208	3.42190057050833	0.33800518593375	1.62560394145772	1.11702145051911	0.273555525077338	0.207925914371647	0.302595071721022	0.639239435149672	NA	NA	NA	0.717792794697579	94.7886666862591
a387	loss_cnaLIHC10_(RB1)	1502	Bicalutamide	ANDR (androgen receptor)	3	12	2.30258509299405	NA	4.22846307946681	4.40166300876479	-0.173199929297986	0.663709270535892	0.541569328335878	0.308135450071609	0.260957526114018	0.319811186187723	0.641030470516126	NA	NA	NA	0.706528533094115	94.7886666862591
a388	loss_cnaLIHC7_(CDKN2A)	154	CHIR-99021	GSK3B	4	13	0.940007258491471	NA	2.84428260759744	3.09198365859127	-0.247701050993821	1.1629792652224	0.838912222229916	0.271312011982142	0.212988363938245	0.295264563359687	0.641969808484093	NA	NA	NA	0.712609662467485	94.7886666862591
a389	loss_cnaLIHC7_(CDKN2A)	151	QS11	ARFGAP	4	13	2.32630161961136	NA	2.72813655564843	3.15058782337594	-0.422451267727512	2.58680669625578	1.18063951906208	0.269704854025352	0.163309948261298	0.357815625266479	0.643929021914923	NA	NA	NA	0.770021724143381	94.7886666862591
a390	TP53_mut	294	MPS-1-IN-1	MPS1	12	5	2.99573227355399	NA	4.25921214273604	3.9991083342501	0.26010380848594	0.909173938440685	1.32915579095709	0.250600852536314	0.28608806025835	0.195690986907296	0.64455906996836	NA	NA	NA	0.70367320751374	94.7886666862591
a391	loss_cnaLIHC7_(CDKN2A)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	12	-2.30258509299405	NA	-0.3388599567165	-0.845347323069537	0.506487366353036	0.560216463360249	2.08391860231585	0.271529660862196	0.904092256259414	0.243045657248886	0.64538111437206	NA	NA	NA	0.458079355661479	94.7886666862591
a392	TP53_mut	1243	piperlongumine	Increases ROS levels	11	5	2.30258509299405	NA	1.27075921163452	1.40484211453002	-0.134082902895501	0.498294498962573	0.599163606980547	0.253426417924282	0.269083650681787	0.22378345636045	0.645686373351953	NA	NA	NA	0.676320526256892	94.7886666862591
a393	loss_cnaLIHC7_(CDKN2A)	1042	BIRB 0796	p38, JNK2	4	9	2.30258509299405	NA	4.10004284212548	3.87170745717876	0.228335384946727	0.920737403510267	0.757202303305023	0.283609845110526	0.247991863995325	0.301551360779137	0.646182323061868	NA	NA	NA	0.682085077668248	94.7886666862591
a394	TP53_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	10	4	0.693147180559945	NA	2.3867955887992	2.59537968992287	-0.208584101123671	0.634760133827004	1.02296811698387	0.277789773940931	0.328603026573371	0.203900881816984	0.647093440511036	NA	NA	NA	0.723691562959398	94.7886666862591
a395	TP53_mut	1091	BMS-536924	IGF1R	11	5	1.38629436111989	NA	1.95506653151502	2.17085706108307	-0.215790529568048	0.59607969916873	1.29750899981982	0.251737088786734	0.362016236870643	0.166311393291309	0.647871112330923	NA	NA	NA	0.737527894194983	94.7886666862591
a396	loss_cnaLIHC10_(RB1)	273	CUDC-101	HDAC, EGFR	3	14	1.63315443905142	NA	-0.142318687199069	-0.690392931725295	0.548074244526226	1.14500469548718	1.95397752377308	0.293639937763569	0.478665499527083	0.280491580818139	0.651029088773782	NA	NA	NA	0.544158636891076	94.7886666862591
a397	loss_cnaLIHC7_(CDKN2A)	164	JQ12	HDAC	3	13	1.63315443905142	NA	0.0873326070648606	0.627008986366439	-0.539676379301578	0.714959183044038	1.97821946380136	0.291511518313088	0.754835229899183	0.272809154483059	0.655999329915236	NA	NA	NA	0.449957101827721	94.7886666862591
a398	TP53_mut	308	XL-880	MET	12	5	1.63315443905142	NA	0.128443113769347	0.493782030630251	-0.365338916860903	1.6611159567663	1.01781998500861	0.240910620997587	0.219935830110325	0.358942565720806	0.657319400467214	NA	NA	NA	0.59045938071562	94.7886666862591
a399	loss_cnaLIHC7_(CDKN2A)	201	Epothilone B	Microtubules	4	13	-3.44201937618241	NA	-5.51398017721481	-5.90645997907384	0.392479801859027	1.33267211217926	1.56010019961974	0.258662358490198	0.294505901543345	0.251573457880904	0.65746366524329	NA	NA	NA	0.639438782512635	94.7886666862591
a400	TP53_mut	166	FTI-277	Farnesyl transferase (FNTA)	12	5	0.0237165266173161	NA	1.87308620757916	1.61164564054604	0.261440567033119	0.843642111958626	1.58476881592454	0.239494379990678	0.309895112307932	0.164970792210217	0.659193727826426	NA	NA	NA	0.741470226042469	94.7886666862591
a401	loss_cnaLIHC7_(CDKN2A)	261	TL-1-85	MAP3K7 (TAK1)	4	13	2.32630161961136	NA	3.21895398047491	2.88671922879255	0.332234751682364	1.62726242242722	1.21707127719841	0.253724738097987	0.20416790009002	0.272978877989085	0.663556328807021	NA	NA	NA	0.724801709071537	94.7886666862591
a402	loss_cnaLIHC7_(CDKN2A)	287	KIN001-244	PDPK1 (PDK1)	4	13	2.99573227355399	NA	3.37857273369948	3.03322039006316	0.345352343636323	2.08291342142219	1.12087880722869	0.252357710793254	0.165802543727679	0.308108549656842	0.665247510141892	NA	NA	NA	0.768464140016503	94.7886666862591
a403	loss_cnaLIHC7_(CDKN2A)	268	YM155	BIRC5 (Survivin)	4	12	1.63315443905142	NA	-1.82988592744004	-2.70725058725918	0.877364659819147	4.53751017510551	3.08135801709101	0.254633956368136	0.193358169119422	0.284733112787534	0.665919323457934	NA	NA	NA	0.737168309924192	94.7886666862591
a404	loss_cnaLIHC10_(RB1)	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	14	2.32630161961136	NA	1.33650741343042	2.1533429401396	-0.816835526709176	2.40094602968839	2.98850768008782	0.280024723976993	0.340214030889812	0.273325557150709	0.666107687144085	NA	NA	NA	0.640226332814521	94.7886666862591
a405	loss_cnaLIHC7_(CDKN2A)	156	AZD6482	PI3Kbeta	4	13	1.63315443905142	NA	2.39441128039304	2.14417059162162	0.250240688771418	1.11975243460541	0.965974429573808	0.25058493049164	0.22347858422795	0.259055189361302	0.667443456937058	NA	NA	NA	0.705360456300551	94.7886666862591
a406	TP53_mut	301	PHA-793887	CDK-pan	12	5	2.32630161961136	NA	3.80434360611182	3.4722000692258	0.332143536886023	1.16269016063999	1.99457690563804	0.23185216900726	0.285668141117836	0.166523304239188	0.669348336990489	NA	NA	NA	0.741194465332605	94.7886666862591
a407	loss_cnaLIHC7_(CDKN2A)	1025	SB 216763	GSK3A, GSK3B	4	6	2.30258509299405	NA	4.6461004884167	4.34051181016951	0.305588678247192	0.836095734178659	1.18816568453944	0.285649034263561	0.36549484198408	0.257193657604785	0.669829232318029	NA	NA	NA	0.646110875874819	94.7886666862591
a408	loss_cnaLIHC7_(CDKN2A)	255	CP724714	ERBB2	4	13	2.32630161961136	NA	4.34367377553951	4.135603238987	0.208070536552506	1.03047394046207	0.780949519117318	0.248641951820686	0.201917320159698	0.266432760964731	0.669853840415519	NA	NA	NA	0.728039837763202	94.7886666862591
a409	loss_cnaLIHC10_(RB1)	253	XMD14-99	EPHB3, CAMK1	3	14	2.32630161961136	NA	4.60772709038851	4.70890672661266	-0.101179636224148	0.134704174150717	0.38939258406956	0.276578161893889	0.75112472840627	0.259839658903401	0.66994875378325	NA	NA	NA	0.453408856475635	94.7886666862591
a410	TP53_mut	179	5-Fluorouracil	DNA antimetabolite	12	5	3.46573590279973	NA	4.26069792391951	3.96054912082894	0.300148803090576	1.25998158959933	1.44106311005048	0.228995641646498	0.238216816474297	0.208282899615731	0.673161278156005	NA	NA	NA	0.697665607271777	94.7886666862591
a411	loss_cnaLIHC10_(RB1)	275	I-BET	BRD2, BRD3, BRD4	3	14	2.99573227355399	NA	4.20528460463148	3.78092990462411	0.42435470000737	1.04207689944276	1.61451605704408	0.273697659772953	0.407220139160833	0.262837088647043	0.673166290322228	NA	NA	NA	0.594526483750482	94.7886666862591
a412	loss_cnaLIHC7_(CDKN2A)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	13	1.63315443905142	NA	0.771410499148405	0.303570314764724	0.467840184383681	2.54879188593181	1.70264062177237	0.245943794386431	0.183553701251934	0.274773301189467	0.673207292067954	NA	NA	NA	0.748591871870619	94.7886666862591
a413	loss_cnaLIHC10_(RB1)	157	JNK-9L	JNK	3	14	1.63315443905142	NA	-0.647070962851979	-0.285740760469291	-0.361330202382687	0.262229662278267	1.42725533891047	0.271238753439892	1.37791506591371	0.253164372577171	0.67591813390718	NA	NA	NA	0.392509721406859	94.7886666862591
a414	loss_cnaLIHC7_(CDKN2A)	305	TPCA-1	IKK	4	13	2.99573227355399	NA	3.40703256989064	3.08926438084244	0.317768189048194	1.95944171092687	1.08707881842032	0.242771065546062	0.162172820592801	0.292313844832296	0.677159753600312	NA	NA	NA	0.773723229406377	94.7886666862591
a415	loss_cnaLIHC10_(RB1)	287	KIN001-244	PDPK1 (PDK1)	3	14	2.99573227355399	NA	2.81012164093112	3.17969936305898	-0.369577722127853	0.5710120847941	1.45357055141951	0.269928352472387	0.647232750356096	0.254255097399253	0.677386602868813	NA	NA	NA	0.487073941793784	94.7886666862591
a416	loss_cnaLIHC10_(RB1)	312	AV-951	VEGFR	3	14	-2.05572501506252	NA	0.505580704129365	0.362060997071798	0.143519707057567	0.346147569928551	0.55571200357727	0.269492118942068	0.414620004662148	0.258262744251863	0.677875757841781	NA	NA	NA	0.591371892541679	94.7886666862591
a417	loss_cnaLIHC7_(CDKN2A)	262	VX-11e	ERK	4	13	1.63315443905142	NA	3.10564865143484	2.75394334111361	0.351705310321232	1.82946336880632	1.34944172294058	0.241200801430233	0.192245068317881	0.260630232741601	0.679119568991995	NA	NA	NA	0.739670259315768	94.7886666862591
a418	TP53_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	12	5	0.246860077931526	2.32630161961136	1.30840671295979	0.979845229498431	0.328561483461361	1.38493294458873	1.69173754864429	0.223054624143129	0.237239993997639	0.194215399264893	0.681121086529426	NA	NA	NA	0.713504567928503	94.7886666862591
a419	TP53_mut	1069	EHT 1864	Rac GTPases	11	5	2.30258509299405	NA	3.35684043031578	3.15200831992891	0.204832110386875	1.00290355484791	0.633612768452756	0.224407829238116	0.204239090984114	0.32327648776249	0.683671374244566	NA	NA	NA	0.629996889156142	94.7886666862591
a420	loss_cnaLIHC10_(RB1)	268	YM155	BIRC5 (Survivin)	3	13	1.63315443905142	NA	-3.22760440581663	-2.31721057995542	-0.910393825861207	1.91796081709228	3.64167261137225	0.263990414903894	0.474667583272848	0.249993319832821	0.686467322155277	NA	NA	NA	0.565768663181168	94.7886666862591
a421	TP53_mut	156	AZD6482	PI3Kbeta	12	5	1.63315443905142	NA	2.26712634776089	2.0492693279045	0.217857019856392	1.05209049179583	0.837706726676862	0.217981678010272	0.207070609947751	0.260063591372388	0.687949023712597	NA	NA	NA	0.661610043839063	94.7886666862591
a422	TP53_mut	175	PAC-1	CASP3 agonist	12	5	0.940007258491471	NA	2.34580877170542	2.57789817873283	-0.232089407027411	1.08759541162287	1.00659617784099	0.217597982324842	0.213396824358696	0.230568535959684	0.688466611746635	NA	NA	NA	0.683338585132332	94.7886666862591
a423	loss_cnaLIHC7_(CDKN2A)	277	ABT-869	VEGFR and PDGFR family	4	13	0.0237165266173161	NA	2.26164310504874	2.34951822938857	-0.0878751243398277	0.48126418865053	0.346060015991996	0.233090456786584	0.182592277614153	0.253930301910002	0.689279784482153	NA	NA	NA	0.75149995715011	94.7886666862591
a424	TP53_mut	211	TL-2-105	CRAF	12	5	2.32630161961136	1.63315443905142	4.22810396675239	4.41882829031086	-0.190724323558472	0.939727057265359	0.697368447451762	0.216329852645798	0.202957148124996	0.273491472485446	0.690178404599543	NA	NA	NA	0.654168939778023	94.7886666862591
a425	TP53_mut	226	GSK1070916	AURKB	12	5	0.940007258491471	2.32630161961136	1.98288926702884	2.38097207750958	-0.398082810480739	1.72017836986661	2.2671644653966	0.211560123479852	0.231419495474534	0.175586207598354	0.696632451025578	NA	NA	NA	0.736395964269573	94.7886666862591
a426	TP53_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	12	5	2.99573227355399	NA	5.59906512436581	5.53604779611791	0.0630173282478967	0.307371442062196	0.278193187685258	0.210150010772937	0.205020114507402	0.226523621129045	0.698545187298515	NA	NA	NA	0.690477062811311	94.7886666862591
a427	TP53_mut	298	OSI-930	KIT, VEGFR, PDGFR	12	5	2.32630161961136	NA	4.45370717525956	4.54932108756465	-0.0956139123050885	0.505974282336906	0.277955233953741	0.209474687468804	0.188969905473226	0.34399032874841	0.699461973310403	NA	NA	NA	0.626208705034975	94.7886666862591
a428	TP53_mut	274	PXD101, Belinostat	HDAC	12	5	2.99573227355399	NA	0.238567372710144	-0.162545193750957	0.4011125664611	1.94523650648192	1.84602977086365	0.208990857303636	0.206202466961993	0.21728390993036	0.70011909486018	NA	NA	NA	0.698474569105076	94.7886666862591
a429	loss_cnaLIHC7_(CDKN2A)	175	PAC-1	CASP3 agonist	4	13	0.940007258491471	NA	2.59608733675547	2.35806513900826	0.238022197747209	1.29402930964551	1.0024023915196	0.223050453502267	0.183938799510201	0.237451745687056	0.701943300385076	NA	NA	NA	0.751684575818071	94.7886666862591
a430	loss_cnaLIHC7_(CDKN2A)	1264	SGC0946	Q8TEK3 (DOT1L)	4	12	-0.693147180559945	NA	1.77048387239406	1.69275925785561	0.0777246145384476	0.548832516487907	0.268259011109792	0.223360607141429	0.141618093322574	0.28973719919752	0.704667897876705	NA	NA	NA	0.800516875950695	94.7886666862591
a431	loss_cnaLIHC10_(RB1)	309	Y-39983	ROCK	3	14	2.99573227355399	NA	3.93105722302721	4.24966510172872	-0.318607878701513	0.812448545218349	1.35953831656293	0.245089640661177	0.392157608720792	0.234350054588378	0.705471477746657	NA	NA	NA	0.614982757251188	94.7886666862591
a432	loss_cnaLIHC10_(RB1)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	11	0.693147180559945	NA	2.59533278027429	2.40577057335096	0.18956220692333	1.32287037563059	0.57491813060421	0.251720948623557	0.143296131212379	0.329720349441946	0.70591620539073	NA	NA	NA	0.829381465030058	94.7886666862591
a433	loss_cnaLIHC7_(CDKN2A)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	10	1.6094379124341	NA	0.758917496152526	1.00357511942487	-0.244657623272342	1.12021453434297	1.06681000828805	0.226449153093902	0.218402471822809	0.229335703050773	0.708584782072556	NA	NA	NA	0.722681581466664	94.7886666862591
a434	loss_cnaLIHC10_(RB1)	1046	681640	WEE1, CHEK1	3	11	0.693147180559945	NA	2.56193894299133	2.33081793171061	0.231121011280722	0.870455115276959	0.943788309767724	0.247992721347727	0.265517437056114	0.244886495084479	0.710048500752247	NA	NA	NA	0.712741286290902	94.7886666862591
a435	TP53_mut	202	GSK-1904529A	IGF1R	12	5	0.0237165266173161	NA	1.69479677614908	1.52408454892296	0.170712227226124	0.873869743749574	0.772922375310016	0.201281663248092	0.195352028660058	0.220865940331527	0.710622551640667	NA	NA	NA	0.699760535327649	94.7886666862591
a436	TP53_mut	276	CAY10603	HDAC6	12	5	2.99573227355399	NA	0.918378087897169	0.617927708379807	0.300450379517362	1.51395314636661	1.43320977554596	0.201259772125546	0.198454212561613	0.209634615004569	0.710652465091878	NA	NA	NA	0.708691320146966	94.7886666862591
a437	TP53_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	12	5	2.32630161961136	NA	1.91812696888469	2.30635964743472	-0.388232678550027	1.58260475088006	2.67822733169248	0.200495641916931	0.245312468785487	0.144958821813191	0.711696929902525	NA	NA	NA	0.773725449334585	94.7886666862591
a438	TP53_mut	1375	Temozolomide	DNA akylating agent	11	5	3.40119738166216	NA	5.71584760328955	5.63036394073181	0.085483662557734	0.404937596666456	0.456669810606601	0.203354177681781	0.211103299030409	0.187189213239616	0.711805618070219	NA	NA	NA	0.729973646125343	94.7886666862591
a439	loss_cnaLIHC7_(CDKN2A)	288	KIN001-055	JAK3, MNK1	4	13	2.32630161961136	NA	4.29573670542241	4.12549746261816	0.170239242804241	1.07581691295148	0.702741765602744	0.215070430129171	0.158241835348353	0.242250071273658	0.712074288084066	NA	NA	NA	0.781508270629627	94.7886666862591
a440	loss_cnaLIHC7_(CDKN2A)	135	Gemcitabine	DNA replication	4	13	0.0237165266173161	NA	-2.10000512019867	-2.57914016857919	0.479135048380518	2.23730171734633	2.24334306476822	0.213695791663419	0.214157547310527	0.213580818692135	0.713825190114239	NA	NA	NA	0.723453328346778	94.7886666862591
a441	TP53_mut	281	CH5424802	ALK	12	5	1.63315443905142	NA	3.97692133876996	4.07118508384998	-0.0942637450800152	0.532382822094339	0.281630264222277	0.196981938186013	0.177060080017592	0.334707441120808	0.716507351816117	NA	NA	NA	0.642678342926532	94.7886666862591
a442	loss_cnaLIHC10_(RB1)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	11	-1.38629436111989	0.693147180559945	-1.64660793949921	-1.86559354419425	0.218985604695044	0.444199551955988	0.97660319960523	0.240704514790951	0.492989251634232	0.224231914029735	0.718154372529437	NA	NA	NA	0.590329057854741	94.7886666862591
a443	loss_cnaLIHC10_(RB1)	276	CAY10603	HDAC6	3	14	2.99573227355399	NA	1.11656854268579	0.768604997757692	0.347963544928099	1.43108192818232	1.50262415537472	0.233019118854651	0.243147186807162	0.231570578499934	0.719284172407462	NA	NA	NA	0.729838307856787	94.7886666862591
a444	loss_cnaLIHC10_(RB1)	257	NPK76-II-72-1	PLK3	3	14	2.32630161961136	NA	2.90322068276014	3.23235704392052	-0.329136361160379	1.85713766884916	1.33359404417041	0.232664490296392	0.17722776651466	0.246804012509763	0.719691547245256	NA	NA	NA	0.79359064543938	94.7886666862591
a445	loss_cnaLIHC7_(CDKN2A)	1495	AZD-2281	PARP1, PARP2	4	12	2.30258509299405	NA	3.60803704275477	3.75851282608066	-0.150475783325895	0.922899806603468	0.653052451203277	0.209154368904793	0.163046716717482	0.230419138690371	0.722563304441306	NA	NA	NA	0.777601767072246	94.7886666862591
a446	loss_cnaLIHC10_(RB1)	1268	XAV 939	TNKS1 (tankyrase-1)	3	13	1.6094379124341	NA	3.19206776911756	3.01012747693173	0.18194029218583	0.641609946700962	0.806628098083901	0.231717853394029	0.283568378453814	0.225556601137524	0.722926263850494	NA	NA	NA	0.697764016640195	94.7886666862591
a447	loss_cnaLIHC7_(CDKN2A)	1022	AZD7762	CHEK1, CHEK2	4	10	0.693147180559945	NA	-0.0240318252318043	0.332223518227257	-0.356255343459062	2.00896872619351	1.53200989633261	0.214080931395754	0.177332448640988	0.232541150231393	0.723746437348221	NA	NA	NA	0.763743435134968	94.7886666862591
a448	loss_cnaLIHC7_(CDKN2A)	1016	Temsirolimus	MTOR	4	10	-1.6094379124341	NA	-2.08554198359581	-2.37926488786068	0.293722904264869	0.828230208234436	1.51312596576201	0.213728096017991	0.354639207003821	0.194116624069001	0.724180801517458	NA	NA	NA	0.652226069817002	94.7886666862591
a449	TP53_mut	293	MP470	PDGFR	12	5	2.99573227355399	NA	3.42280853010691	3.13969029845384	0.283118231653076	1.64596111785088	0.898713019368742	0.190786346430286	0.172007849142112	0.315026293768325	0.725019585045246	NA	NA	NA	0.65642027891729	94.7886666862591
a450	loss_cnaLIHC7_(CDKN2A)	1028	VX-702	p38	4	10	0.693147180559945	NA	3.21503317956619	3.13053798285964	0.0844951967065475	0.463059341049577	0.372605823912263	0.212751036656993	0.182471638548592	0.226768319988588	0.725384150599943	NA	NA	NA	0.75910979388018	94.7886666862591
a451	loss_cnaLIHC7_(CDKN2A)	200	LAQ824	HDAC	4	13	0.0237165266173161	NA	-2.62220886582325	-2.83290118115559	0.210692315332337	0.802189076659146	1.07996429268001	0.204472809545728	0.262646701959345	0.195091927353902	0.725615249637579	NA	NA	NA	0.686907332122812	94.7886666862591
a452	loss_cnaLIHC7_(CDKN2A)	222	BX-912	PDPK1 (PDK1)	4	13	2.32630161961136	NA	3.30486273155999	2.97885466048852	0.326008071071474	2.47988559389019	1.28306194826769	0.204275778222621	0.131460931856968	0.254085994453837	0.725867918594408	NA	NA	NA	0.814585531821743	94.7886666862591
a453	TP53_mut	154	CHIR-99021	GSK3B	12	5	0.940007258491471	NA	2.98269989315241	3.15610385484947	-0.173403961697058	0.979346767444591	0.713105332594274	0.189316481691099	0.177060840410512	0.243167388843125	0.727044621153344	NA	NA	NA	0.692331271672339	94.7886666862591
a454	loss_cnaLIHC7_(CDKN2A)	1046	681640	WEE1, CHEK1	4	10	0.693147180559945	NA	2.23964300248799	2.43662420678388	-0.196981204295884	1.02771074056618	0.898716953920854	0.2112082977744	0.191669889707841	0.219180469931617	0.727285751106169	NA	NA	NA	0.751003271267571	94.7886666862591
a455	TP53_mut	305	TPCA-1	IKK	12	5	2.99573227355399	NA	3.23584715694885	2.99168026942562	0.244166887523226	1.17407392645927	1.63053897402187	0.186184257157547	0.207965513943041	0.149746121628094	0.731366898281949	NA	NA	NA	0.771965295703365	94.7886666862591
a456	loss_cnaLIHC7_(CDKN2A)	345	KIN001-270	CDK9	4	13	2.99573227355399	NA	4.82765428780915	4.64339746700079	0.184256820808363	0.990842133273696	0.912368627887268	0.198425596804879	0.185959816019921	0.201954358333252	0.733384946406502	NA	NA	NA	0.754764486751365	94.7886666862591
a457	TP53_mut	185	OSI-906	IGF1R	12	5	0.940007258491471	NA	1.80967193865111	2.0608947640343	-0.251222825383186	1.26603436417912	1.64267559805937	0.182497102468202	0.198432864455521	0.152935141716342	0.736467009496934	NA	NA	NA	0.769668798432197	94.7886666862591
a458	loss_cnaLIHC10_(RB1)	235	QL-XII-47	BTK, BMX	3	14	2.32630161961136	NA	2.47122898819965	1.94852768308466	0.522701305114988	2.04245690659946	2.45091058626683	0.217749653191656	0.255917911132454	0.21326820653672	0.736902864515989	NA	NA	NA	0.72155615723394	94.7886666862591
a459	loss_cnaLIHC7_(CDKN2A)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	10	2.30258509299405	NA	4.4713616735024	4.35324177503167	0.118119898470724	0.452287869909243	0.617632719787254	0.203400087179686	0.261160880778045	0.191246180272656	0.736939134849672	NA	NA	NA	0.703327578727939	94.7886666862591
a460	loss_cnaLIHC10_(RB1)	310	YM201636	FYV1	3	14	1.63315443905142	NA	2.22947675947691	2.52628030852173	-0.296803549044819	0.911799581072835	1.42868208949423	0.21647590979613	0.325514022166578	0.20774639174618	0.738379654857034	NA	NA	NA	0.669425192369582	94.7886666862591
a461	TP53_mut	238	CAL-101	PI3Kdelta	12	5	2.99573227355399	2.32630161961136	4.77803139966123	4.9704211066197	-0.192389706958465	1.00858844689925	1.19995067148443	0.180988836690651	0.190751448274008	0.160331346554825	0.738556970395138	NA	NA	NA	0.762549369308582	94.7886666862591
a462	loss_cnaLIHC10_(RB1)	158	PF-562271	FAK	3	12	0.940007258491471	NA	1.33633514470621	1.54202696127983	-0.205691816573625	0.400749272515702	1.00388988427226	0.219585691677616	0.513268097237947	0.204894799515521	0.739154396424909	NA	NA	NA	0.592459954759297	94.7886666862591
a463	loss_cnaLIHC10_(RB1)	179	5-Fluorouracil	DNA antimetabolite	3	14	3.46573590279973	NA	3.94026123730059	4.22216692709122	-0.281905689790632	0.310910539292519	1.40597716008055	0.214571485309024	0.906709982981317	0.200505170208085	0.740589648280036	NA	NA	NA	0.508987815258451	94.7886666862591
a464	TP53_mut	192	LFM-A13	BTK	12	5	2.77258872223978	NA	4.68328230815968	4.83427251033553	-0.150990202175849	0.904875223899969	0.687570594566635	0.177143367523933	0.166863008498661	0.21959956311252	0.743895141032595	NA	NA	NA	0.716067712137524	94.7886666862591
a465	loss_cnaLIHC7_(CDKN2A)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	13	3.68887945411394	NA	4.09156529040188	3.76120325028677	0.33036204011511	2.17939592115416	1.60800018780282	0.190149692933529	0.151584224283653	0.205449005927369	0.744066997670372	NA	NA	NA	0.792749276238477	94.7886666862591
a466	loss_cnaLIHC10_(RB1)	283	GSK2126458	PI3K, MTOR	3	14	-2.05572501506252	0.0237165266173161	-1.56861848270963	-1.97963345975274	0.411014977043112	1.78320925668336	1.96861407994326	0.211328002167946	0.230491724682705	0.208783926332051	0.744358985256356	NA	NA	NA	0.744716006184536	94.7886666862591
a467	loss_cnaLIHC7_(CDKN2A)	224	AS605240	PI3Kgamma	4	13	2.99573227355399	2.32630161961136	3.59745154639651	3.94580898633376	-0.348357439937258	2.64098040855622	1.58816727853138	0.188569397895621	0.131904590737839	0.219345559278487	0.746113019542071	NA	NA	NA	0.81568767739884	94.7886666862591
a468	loss_cnaLIHC10_(RB1)	226	GSK1070916	AURKB	3	14	0.940007258491471	2.32630161961136	1.77743683571808	2.16908722033856	-0.391650384620481	1.28752619208315	1.96065497992041	0.207789133215833	0.304188285278151	0.199754872035864	0.748479311911624	NA	NA	NA	0.687372327161253	94.7886666862591
a469	TP53_mut	329	QL-XI-92	DDR1	12	5	2.32630161961136	NA	4.19601161555222	4.34549086888638	-0.149479253334155	0.89143592747148	0.790914372717959	0.172654271008605	0.167683676109114	0.188995494949059	0.750143972042647	NA	NA	NA	0.740856235137227	94.7886666862591
a470	TP53_mut	153	Midostaurin	KIT	12	5	-0.669430653942629	NA	-0.452605907872739	-0.682400359217461	0.229794451344722	1.4439829345033	0.957048156347205	0.172562588480533	0.159139312421145	0.240107511644749	0.750271784646199	NA	NA	NA	0.707566916568671	94.7886666862591
a471	TP53_mut	1259	BMN-673	PARP1	11	5	2.30258509299405	NA	2.44642493853517	2.59276236071058	-0.146337422175407	0.838073948651488	0.832104635388574	0.174966744541172	0.174611586973766	0.175864207398713	0.750433568417164	NA	NA	NA	0.753411864386678	94.7886666862591
a472	loss_cnaLIHC7_(CDKN2A)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	13	1.63315443905142	NA	2.49107817845452	2.70502643872273	-0.213948260268207	1.82255333758246	0.927099098755571	0.184004477927636	0.117389299866527	0.230771727159897	0.752034308274756	NA	NA	NA	0.833833959720666	94.7896073094759
a473	TP53_mut	257	NPK76-II-72-1	PLK3	12	5	2.32630161961136	NA	3.10387654939486	3.34322841408586	-0.239351864690998	1.32787501221105	1.63460554594564	0.169012242831855	0.180251802684691	0.146427904447449	0.755227024396628	NA	NA	NA	0.781104442320175	94.8961249770509
a474	TP53_mut	330	XMD13-2	RIPK	12	5	2.32630161961136	NA	4.00588366538923	3.83922570142513	0.166657963964103	0.952527197885769	1.10017673930482	0.167656005844693	0.174963995079634	0.15148290089228	0.757122882436846	NA	NA	NA	0.776486486475376	94.8961249770509
a475	TP53_mut	346	THZ-2-102-1	CDK7	12	4	0.916290731874155	2.99573227355399	-0.441049398402067	-0.862133479919043	0.421084081516976	2.35760633741212	2.49920414533493	0.176284981242463	0.178606612492902	0.168487269158456	0.764603904244563	NA	NA	NA	0.779353138816092	94.8961249770509
a476	loss_cnaLIHC7_(CDKN2A)	155	AP-24534	ABL	4	13	-0.669430653942629	NA	-0.198416599799002	0.0515157901499271	-0.249932389948929	0.773767979678925	1.55834365534433	0.174030943896082	0.323006891617095	0.160383359018267	0.765026928368586	NA	NA	NA	0.674953929935806	94.8961249770509
a477	loss_cnaLIHC10_(RB1)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	11	1.6094379124341	NA	1.58460329192762	1.7708380066683	-0.18623471474068	0.397963402976314	1.01330207413241	0.198296405875273	0.467969449823416	0.183789927500282	0.766004520352179	NA	NA	NA	0.63726149859029	94.8961249770509
a478	loss_cnaLIHC7_(CDKN2A)	293	MP470	PDGFR	4	13	2.99573227355399	NA	3.14360413033953	3.39982594863031	-0.256221818290774	1.68549576831851	1.4315263740825	0.172447365861672	0.152015699538888	0.178985049056461	0.767096713477363	NA	NA	NA	0.795659359578837	94.8961249770509
a479	loss_cnaLIHC10_(RB1)	286	KIN001-236	TIE2	3	14	2.32630161961136	NA	4.17319492840998	4.33856832893847	-0.165373400528487	0.741096255968417	0.892081765245121	0.189331476903272	0.223146992305861	0.185379196135733	0.770095596495057	NA	NA	NA	0.755520897617851	94.8961249770509
a480	loss_cnaLIHC10_(RB1)	197	Bryostatin 1	PRKC	3	14	-4.8283137373023	NA	-2.9162661740866	-2.77215926873487	-0.144106905351729	0.427362189986098	0.805766314841506	0.188083089090031	0.337200877214751	0.178844539288138	0.77156499082407	NA	NA	NA	0.676114995217132	94.8961249770509
a481	loss_cnaLIHC7_(CDKN2A)	303	PIK-93	PI4K, PI3K	4	13	2.99573227355399	NA	3.09482386894321	2.84677520844213	0.248048660501076	2.34003096469968	1.15545348524578	0.168650575461232	0.106002298363992	0.214676457052109	0.772066676034192	NA	NA	NA	0.849427901049618	94.8961249770509
a482	loss_cnaLIHC7_(CDKN2A)	202	GSK-1904529A	IGF1R	4	13	0.0237165266173161	NA	1.75406547904674	1.61090170324744	0.1431637757993	1.25349013620362	0.713922163795255	0.16848681937594	0.114212127933365	0.200531350698278	0.772281265160085	NA	NA	NA	0.839293728061987	94.8961249770509
a483	TP53_mut	208	SB-715992	KIF11	12	5	-2.05572501506252	NA	-0.742988669947418	-1.00177955018729	0.258790880239875	1.57485986812965	1.87065623977796	0.156001116124727	0.164326290533534	0.138342296535783	0.773480310824587	NA	NA	NA	0.794196872527937	94.8961249770509
a484	loss_cnaLIHC7_(CDKN2A)	1268	XAV 939	TNKS1 (tankyrase-1)	4	12	1.6094379124341	NA	2.94460913505332	3.077451997271	-0.132842862217676	0.599098317328363	0.830230090460178	0.168916441191609	0.221737999215354	0.160007284419244	0.774140720103574	NA	NA	NA	0.738952452977239	94.8961249770509
a485	loss_cnaLIHC7_(CDKN2A)	309	Y-39983	ROCK	4	13	2.99573227355399	NA	4.35822989224095	4.14273565571691	0.215494236524039	1.50900440617078	1.24586271752419	0.165414860480702	0.142805571436914	0.172967882811578	0.776310360649655	NA	NA	NA	0.806966686804634	94.8961249770509
a486	TP53_mut	1036	PLX4720	BRAF	10	4	2.30258509299405	NA	3.96939196423351	3.81916684762124	0.150225116612262	0.561880481383924	1.48323432395018	0.16936215499148	0.267361336777982	0.101282119882568	0.779550283926866	NA	NA	NA	0.855190954176744	94.8961249770509
a487	loss_cnaLIHC7_(CDKN2A)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	12	1.38629436111989	NA	1.31663702078739	1.48460736614489	-0.167970345357496	0.89006388892645	1.05416040418196	0.164480230877797	0.18871717799954	0.159340404639694	0.779900754701031	NA	NA	NA	0.765752814689555	94.8961249770509
a488	TP53_mut	165	DMOG	Prolyl-4-Hydroxylase	12	5	8.29404964010203	NA	5.17067640470595	5.03204230420143	0.138634100504516	1.034561976025	0.603837705981782	0.147605733744116	0.13400270231966	0.229588346555985	0.785332723979992	NA	NA	NA	0.736199037758276	94.8961249770509
a489	loss_cnaLIHC10_(RB1)	228	KIN001-102	AKT1	3	13	2.32630161961136	NA	3.57525354626672	3.25976800698491	0.315485539281806	2.0925671099059	1.73636247224231	0.176092480134662	0.150764837021639	0.181693364332156	0.78739000202506	NA	NA	NA	0.825725483195634	94.8961249770509
a490	TP53_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	12	5	3.68887945411394	NA	3.91341767787523	3.66017825616656	0.253239421708669	1.68204608357965	1.88829956378701	0.145586756943518	0.150554389788023	0.134109770803947	0.788191402448524	NA	NA	NA	0.802571233464788	94.8961249770509
a491	TP53_mut	205	BMS-708163	g-secretase	12	5	2.32630161961136	0.940007258491471	4.73261393144849	4.80363458472107	-0.0710206532725817	0.548985870338586	0.259270576968361	0.145290996328495	0.129366996692975	0.273924847558959	0.788610436674115	NA	NA	NA	0.722810972611678	94.8961249770509
a492	loss_cnaLIHC10_(RB1)	229	LY317615	PRKCB (PKCbeta)	3	14	2.99573227355399	2.32630161961136	4.33315192537266	4.04480921233744	0.288342713035223	1.31932845798906	1.72286600536182	0.172176910546322	0.218552636600229	0.167362239511289	0.790364399459796	NA	NA	NA	0.763657674291039	94.8961249770509
a493	TP53_mut	263	FR-180204	ERK	12	5	2.99573227355399	NA	5.1944010186649	5.0994828319046	0.0949181867602977	0.55124647587472	0.895841714260406	0.143609761361676	0.172188287661488	0.105954193971265	0.790993691633417	NA	NA	NA	0.833937005821554	94.8961249770509
a494	loss_cnaLIHC10_(RB1)	1377	Afatinib (rescreen)	ERBB2, EGFR	3	13	2.30258509299405	NA	3.6180182442804	3.87110379912962	-0.253085554849219	1.04709026495156	1.52625078888469	0.172470909497481	0.241703665214504	0.165821735649462	0.791649713642689	NA	NA	NA	0.747870682984172	94.8961249770509
a495	loss_cnaLIHC10_(RB1)	1192	GSK269962A	ROCK1, ROCK2	3	13	1.6094379124341	NA	1.38975467813346	1.56977318155722	-0.180018503423763	1.40057331988057	0.974879707392245	0.172044139747073	0.128532009619542	0.184657144936685	0.792152140849831	NA	NA	NA	0.848980654770389	94.8961249770509
a496	TP53_mut	1030	KU-55933	ATM	10	4	2.30258509299405	NA	3.63458318857578	3.51346365668053	0.121119531895254	0.664463950920405	0.994171782142753	0.159281150677541	0.182281569568192	0.121829581236155	0.792322816394162	NA	NA	NA	0.833104469166758	94.8961249770509
a497	TP53_mut	255	CP724714	ERBB2	12	5	2.32630161961136	NA	4.21965817591706	4.10032781959687	0.119330356320198	0.712808836876465	1.11773470166221	0.142043949695407	0.167408637697457	0.106760894282641	0.793215267135121	NA	NA	NA	0.83337157558325	94.8961249770509
a498	loss_cnaLIHC7_(CDKN2A)	1047	Nutlin-3a	MDM2	4	10	2.07944154167984	1.38629436111989	4.00659603591775	4.18343954086625	-0.176843504948497	1.84143725590039	0.77936299805191	0.15490684701997	0.0960355854547035	0.226907750804867	0.797884907927189	NA	NA	NA	0.863221211394667	94.8961249770509
a499	TP53_mut	1006	Cytarabine	DNA synthesis	10	4	0.693147180559945	NA	0.237912090098064	0.0711798401400749	0.166732249957989	1.09293848390143	1.07323525823782	0.153240056315347	0.152554102919691	0.15535480098907	0.800007366434347	NA	NA	NA	0.803136588142054	94.8961249770509
a500	TP53_mut	303	PIK-93	PI4K, PI3K	12	5	2.99573227355399	NA	2.8457445215833	3.04768778530419	-0.201943263720892	1.41280292881345	1.62297913111745	0.137209521510169	0.142938027379725	0.124427517180612	0.800085964727535	NA	NA	NA	0.815622808199998	94.8961249770509
a501	TP53_mut	231	FMK	RSK	12	5	2.99573227355399	2.32630161961136	4.98646490533317	4.87896823197871	0.107496673354458	0.795428369994139	0.825694586377074	0.133767079530707	0.13514312213336	0.130189388580255	0.80498882698661	NA	NA	NA	0.811556897242519	94.8961249770509
a502	TP53_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	12	5	2.32630161961136	NA	4.74197025051251	4.81071219952728	-0.068741949014762	0.548385179626125	0.412911733485373	0.133285360608428	0.125353404082927	0.166480977507018	0.805675590421653	NA	NA	NA	0.783193089685733	94.8961249770509
a503	loss_cnaLIHC10_(RB1)	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	12	2.30258509299405	NA	3.87946579518538	3.73517259006665	0.144293205118727	0.562840024905278	0.959501547739808	0.158598194448367	0.256366283018004	0.150383504287848	0.809751437735321	NA	NA	NA	0.748067765763657	94.8961249770509
a504	TP53_mut	230	GSK429286A	ROCK2	12	5	2.99573227355399	2.32630161961136	4.88795520377582	4.71337713984308	0.174578063932748	1.16764732533871	1.78275756205294	0.128444253685548	0.149512665463526	0.0979258580351847	0.812586409922038	NA	NA	NA	0.84742120396312	94.8961249770509
a505	loss_cnaLIHC7_(CDKN2A)	253	XMD14-99	EPHB3, CAMK1	4	13	2.32630161961136	NA	4.72963844349533	4.67917858998165	0.0504598535136775	0.172944991473103	0.401581244408766	0.137336365583258	0.291768226901934	0.125652913865456	0.813431274875341	NA	NA	NA	0.726390511302013	94.8961249770509
a506	TP53_mut	1007	Docetaxel	Microtubules	10	4	-4.38202663467388	NA	-4.75078015388844	-4.96056816420114	0.209788010312697	1.60662085748856	1.04353113983881	0.141177398235291	0.130577173410181	0.201036655547339	0.815416436749336	NA	NA	NA	0.779993703932934	94.8961249770509
a507	loss_cnaLIHC10_(RB1)	274	PXD101, Belinostat	HDAC	3	14	2.99573227355399	NA	0.35905498863827	0.0694941098465807	0.28956087879169	1.47554143295317	1.98573679892107	0.150379269260192	0.196240425599001	0.145820372039749	0.816344648328206	NA	NA	NA	0.788141577439182	94.8961249770509
a508	TP53_mut	184	BMS-754807	IGF1R	12	5	0.940007258491471	NA	0.600476359657947	0.422204017914153	0.178272341743794	1.40642834324792	1.44627736886211	0.125795110586026	0.12675536766566	0.123262899345548	0.816375004168607	NA	NA	NA	0.821779197148565	94.8961249770509
a509	loss_cnaLIHC10_(RB1)	292	Masitinib	KIT	3	14	2.99573227355399	NA	3.97952884316233	3.83637908897435	0.143149754187978	0.602564565997735	0.995218430510121	0.150325460722191	0.237567494449243	0.143837523300893	0.816409072142792	NA	NA	NA	0.757606535289068	94.8961249770509
a510	loss_cnaLIHC7_(CDKN2A)	228	KIN001-102	AKT1	4	12	2.32630161961136	NA	3.13828085533803	3.37913510902099	-0.240854253682964	2.35466582900378	1.60602137266622	0.134333569731935	0.102288082969661	0.14996951957315	0.819382791297192	NA	NA	NA	0.858357687988879	94.8961249770509
a511	loss_cnaLIHC7_(CDKN2A)	1026	17-AAG	HSP90	4	10	0	NA	0.229749625983179	0.440024130932728	-0.210274504949548	2.13502527155444	1.26707113581241	0.137352630987957	0.0984880637016791	0.165953196317369	0.820319497109475	NA	NA	NA	0.862926309368747	94.8961249770509
a512	TP53_mut	1378	Bleomycin (50 uM)	DNA damage	11	5	3.91202300542815	NA	2.18520813965756	2.04192561062086	0.143282529036704	1.05489570290857	1.42112584206337	0.122330224660834	0.135826251487843	0.100823252097554	0.823852667490005	NA	NA	NA	0.846775773785965	94.8961249770509
a513	TP53_mut	1170	CCT018159	HSP90	7	3	2.30258509299405	NA	2.99576830023255	2.91539880786402	0.0803694923685216	0.34139548401429	0.82451538465567	0.158420957296582	0.235414632389096	0.0974748244413718	0.824183781842164	NA	NA	NA	0.883770592412554	94.8961249770509
a514	TP53_mut	1175	AG-014699	PARP1, PARP2	11	4	1.6094379124341	NA	3.74003766580058	3.84238167929808	-0.102344013497494	0.871728500506027	0.24461583796871	0.132307035838428	0.117403541857453	0.418386701152955	0.824257475701936	NA	NA	NA	0.729810556485296	94.8961249770509
a515	loss_cnaLIHC7_(CDKN2A)	1218	JQ1	BRD2, BRD3, BRD4	4	12	0	NA	1.6063546205062	1.46260260552502	0.143752014981177	1.37395289625107	1.01483616386229	0.130483316548957	0.104626596278093	0.141650465464377	0.824464696194458	NA	NA	NA	0.856413104386684	94.8961249770509
a516	TP53_mut	310	YM201636	FYV1	12	5	1.63315443905142	NA	2.52189328274511	2.35872704095874	0.163166241786367	1.27310858833398	1.61959060917584	0.118746401590115	0.128163648632588	0.100745361736443	0.826478333616128	NA	NA	NA	0.847236146983324	94.8961249770509
a517	TP53_mut	150	Bicalutamide	ANDR (androgen receptor)	12	5	0.0237165266173161	NA	2.57578617715377	2.53517768434795	0.0406084928058186	0.377453262765376	0.2872922229762	0.114180332425769	0.107585486235578	0.141349084862567	0.833040222149034	NA	NA	NA	0.81440862469015	94.8961249770509
a518	loss_cnaLIHC10_(RB1)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	11	0.693147180559945	NA	1.4691900741919	1.66145542653122	-0.192265352339318	2.13916448205269	1.16513767434545	0.139706221737969	0.0898787138400993	0.165015136470742	0.833765996428887	NA	NA	NA	0.892937386250848	94.8961249770509
a519	loss_cnaLIHC10_(RB1)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	13	0	NA	-1.69696405199664	-1.93296580502245	0.236001753025813	2.37104392959236	1.61904300171157	0.135135315929621	0.0995349559239874	0.145766204341901	0.83594303011505	NA	NA	NA	0.882433104389362	94.8961249770509
a520	loss_cnaLIHC10_(RB1)	193	GW-2580	CSF1R (cFMS)	3	14	2.99573227355399	NA	5.07022850671051	5.13635320855429	-0.066124701843786	0.497839006541103	0.496872190990091	0.133047366337928	0.132823464965529	0.133081913302539	0.837163984558158	NA	NA	NA	0.848266543662446	94.8961249770509
a521	loss_cnaLIHC7_(CDKN2A)	283	GSK2126458	PI3K, MTOR	4	13	-2.05572501506252	0.0237165266173161	-1.73194962463283	-1.96099426047199	0.229044635839163	2.19353246908715	1.88331597899333	0.117500198856738	0.104418165250356	0.121617741469805	0.839942915534007	NA	NA	NA	0.858726531439695	94.8961249770509
a522	loss_cnaLIHC10_(RB1)	224	AS605240	PI3Kgamma	3	14	2.99573227355399	2.32630161961136	4.05393264674422	3.82310893340659	0.230823713337625	1.75553430446366	1.86604064648181	0.124655865441989	0.13148345364185	0.123697044741664	0.847290403732308	NA	NA	NA	0.850934466255529	94.8961249770509
a523	TP53_mut	287	KIN001-244	PDPK1 (PDK1)	12	5	2.99573227355399	NA	3.07325521400794	3.21341868750475	-0.140163473496806	1.27895629084734	1.61202340429302	0.101886563763955	0.109592074803389	0.0869487832022374	0.850770089861835	NA	NA	NA	0.868108689566415	94.8961249770509
a524	loss_cnaLIHC7_(CDKN2A)	205	BMS-708163	g-secretase	4	13	2.32630161961136	0.940007258491471	4.79445970200255	4.74090009945977	0.0535596025427818	0.554054177181891	0.471895526907532	0.109432201142554	0.0966685294481567	0.113498856184913	0.850785600590314	NA	NA	NA	0.868926751174136	94.8961249770509
a525	loss_cnaLIHC7_(CDKN2A)	157	JNK-9L	JNK	4	13	1.63315443905142	NA	-0.458666875260965	-0.31591661800632	-0.142750257254645	0.951589186396622	1.41900615144969	0.106637971719465	0.150012483638236	0.100598758581003	0.854548187518105	NA	NA	NA	0.823258611651225	94.8961249770509
a526	loss_cnaLIHC7_(CDKN2A)	197	Bryostatin 1	PRKC	4	13	-4.8283137373023	NA	-2.73519209555366	-2.81678922325641	0.0815971277027492	0.532616299330953	0.815758767736272	0.106310993951877	0.153200583243974	0.10002605050655	0.854988721854005	NA	NA	NA	0.821327451008673	94.8961249770509
a527	loss_cnaLIHC7_(CDKN2A)	1031	Elesclomol	HSP70	4	10	-1.6094379124341	NA	-3.49838498867781	-3.3319131695136	-0.166471819164214	1.69371478850589	1.44357599785402	0.110246209030284	0.0982879882102626	0.115319054495008	0.855283379812038	NA	NA	NA	0.869597238641647	94.8961249770509
a528	loss_cnaLIHC10_(RB1)	1373	Dabrafenib	BRAF	3	12	2.30258509299405	NA	3.86537840816975	3.74086077854358	0.124517629626173	0.812297652731088	1.09679410429255	0.117689688196627	0.153290643162052	0.113528718962698	0.858140842362198	NA	NA	NA	0.836392330965665	94.8961249770509
a529	TP53_mut	283	GSK2126458	PI3K, MTOR	12	5	-2.05572501506252	0.0237165266173161	-1.85236212294728	-2.03847568185998	0.186113558912703	1.78561449725987	2.343230151437	0.0954445068409726	0.1042294174909	0.0794260686678889	0.860094707770398	NA	NA	NA	0.878575341141046	94.8961249770509
a530	TP53_mut	1194	SB-505124	TGFR1 (ALK5)	11	5	2.30258509299405	NA	3.91022646129401	3.80651046081575	0.103716000478263	1.11339834608987	0.962875527711286	0.0967004268131207	0.0931526446419667	0.10771485772911	0.860280933438432	NA	NA	NA	0.853556306539828	94.8961249770509
a531	loss_cnaLIHC7_(CDKN2A)	1010	Gefitinib	EGFR	4	10	-0.693147180559945	NA	1.16650031621122	1.05415906671869	0.112341249492532	0.865574389133378	1.1243011236123	0.105432721320906	0.129788093204801	0.0999209616829234	0.861528225412708	NA	NA	NA	0.846501111124354	94.8961249770509
a532	loss_cnaLIHC10_(RB1)	299	OSI-027	MTORC1/2	3	14	2.99573227355399	NA	2.23600792843995	1.90675920448773	0.329248723952217	3.36271829598722	2.84384127005449	0.112819775284681	0.097911479633936	0.11577605523177	0.861620550847958	NA	NA	NA	0.885769427003523	94.8961249770509
a533	loss_cnaLIHC10_(RB1)	225	Genentech Cpd 10	AURKA, AURKB	3	14	2.32630161961136	NA	2.88513570116077	2.67167559768953	0.213460103471245	1.39847197147045	2.0038939913366	0.110363691600716	0.152638099172483	0.106522652592449	0.864600655343654	NA	NA	NA	0.836344084362283	94.8961249770509
a534	TP53_mut	1017	Olaparib	PARP1, PARP2	10	4	1.6094379124341	NA	3.99369565521591	4.06084919027943	-0.0671535350635186	0.705586371343782	0.494799339892424	0.101865277095538	0.0951740818570877	0.135718724034916	0.866162840413469	NA	NA	NA	0.845234379428802	94.8961249770509
a535	loss_cnaLIHC7_(CDKN2A)	152	CP466722	ATM	4	12	2.77258872223978	NA	2.83675296707478	2.98863115367341	-0.151878186598635	2.29083051887687	1.30361825595519	0.0968377354013236	0.0662983076867236	0.116505108688702	0.869196146914664	NA	NA	NA	0.906347734014291	94.8961249770509
a536	TP53_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	10	4	-1.6094379124341	NA	0.364426738834403	0.281235204541398	0.0831915342930047	0.880179948158857	0.811444361429188	0.0963412313106845	0.0945165070699726	0.1025227831351	0.87334956057209	NA	NA	NA	0.871250646075716	94.8961249770509
a537	TP53_mut	253	XMD14-99	EPHB3, CAMK1	12	5	2.32630161961136	NA	4.70038509046358	4.66865087163595	0.0317342188276344	0.326010463552436	0.463697867636237	0.0862807294899092	0.0973411051959387	0.0684372757403519	0.873395718019753	NA	NA	NA	0.893941363928914	94.8961249770509
a538	loss_cnaLIHC7_(CDKN2A)	190	Bleomycin	DNA damage	4	13	4.15888308335967	NA	1.21637829541261	1.44039237829423	-0.224014082881623	2.76290043115	2.34692151362526	0.091967086730923	0.0810793180803775	0.0954501808352302	0.8743611306817	NA	NA	NA	0.8898201990869	94.8961249770509
a539	loss_cnaLIHC7_(CDKN2A)	1017	Olaparib	PARP1, PARP2	4	10	1.6094379124341	NA	4.05766591482376	3.99496896539818	0.0626969494255758	0.542751860097213	0.693867019090392	0.0950900046771972	0.115516784068407	0.0903587397881612	0.87497905766496	NA	NA	NA	0.862387310050244	94.8961249770509
a540	loss_cnaLIHC10_(RB1)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	14	2.32630161961136	NA	2.19501753061102	1.99744780513978	0.197569725471245	0.527026792021338	2.07776952593073	0.101638482719725	0.374876056516015	0.095087411286747	0.875204313360179	NA	NA	NA	0.759674853656827	94.8961249770509
a541	loss_cnaLIHC7_(CDKN2A)	1053	MK-2206	AKT1, AKT2	4	10	1.38629436111989	0.693147180559945	1.35416552833274	1.22460702899914	0.129558499333602	1.31266335873052	1.39086275792491	0.0944489175317599	0.0986989531412666	0.0931497364462443	0.875814190608774	NA	NA	NA	0.875215774554198	94.8961249770509
a542	loss_cnaLIHC7_(CDKN2A)	1059	AZD8055	MTORC1/2	4	10	0.693147180559945	NA	-0.0914862888376226	-0.157229976002014	0.0657436871643915	0.675524127223324	0.723384422650365	0.092372817974963	0.0973224856299723	0.0908834709538217	0.878519755690379	NA	NA	NA	0.877285744398712	94.8961249770509
a543	loss_cnaLIHC7_(CDKN2A)	306	TG101348	JAK2	4	13	2.32630161961136	NA	3.01539973020826	2.865902851381	0.149496878827259	2.47750736936455	1.4430290265508	0.0878865215024011	0.0603416484955211	0.103599356684179	0.879887997103084	NA	NA	NA	0.914610570570038	94.8961249770509
a544	loss_cnaLIHC10_(RB1)	221	TAK-715	p38a	3	14	2.99573227355399	2.32630161961136	4.21315842703073	4.31812150906175	-0.104963082031029	1.54914825180586	0.984524092876609	0.0974544852759575	0.0677553500180967	0.106613015151661	0.880297995974611	NA	NA	NA	0.91922946684358	94.8961249770509
a545	TP53_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	12	5	2.77258872223978	NA	4.73210378628993	4.65283154535922	0.0792722409307069	1.03681680573223	0.833207608087162	0.0803458176687994	0.0764573263979092	0.0951410430741221	0.882031478191852	NA	NA	NA	0.871777685291777	94.8961249770509
a546	loss_cnaLIHC7_(CDKN2A)	1091	BMS-536924	IGF1R	4	12	1.38629436111989	NA	2.07681452153398	2.00439658882872	0.0724179327052608	0.377498185211624	0.95365563981484	0.0838948721786829	0.191836505557407	0.075937193345096	0.886537308793708	NA	NA	NA	0.831575479741339	94.8961249770509
a547	loss_cnaLIHC10_(RB1)	1230	IOX2	EGLN1	3	13	-2.30258509299405	NA	0.0898927658219463	0.0626892304805269	0.0272035353414194	0.290550526823489	0.296992551823866	0.0918787415132547	0.0936275546935961	0.0915966921539254	0.887982473341013	NA	NA	NA	0.893350626985098	94.8961249770509
a548	loss_cnaLIHC7_(CDKN2A)	282	EKB-569	EGFR	4	13	0.916290731874155	2.99573227355399	2.16774310638494	2.02849676745048	0.139246338934458	1.64201363397525	1.7442931527664	0.0807542243309919	0.0848021819388602	0.0798296655087002	0.889563580658437	NA	NA	NA	0.889235076966368	94.8961249770509
a549	TP53_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	10	4	2.30258509299405	NA	4.40089233887	4.35223526390657	0.0486570749634287	0.505361290743563	0.770608776701592	0.0834459500341179	0.0962817608998845	0.0631410858979491	0.890171044629832	NA	NA	NA	0.912656051530337	94.8961249770509
a550	TP53_mut	275	I-BET	BRD2, BRD3, BRD4	12	5	2.99573227355399	NA	3.88939232573828	3.77523291395453	0.114159411783752	1.43834780007691	1.8506800620963	0.07322590919219	0.0793684335441316	0.0616851146353419	0.892411844921596	NA	NA	NA	0.905825540001997	94.8961249770509
a551	loss_cnaLIHC7_(CDKN2A)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	7	2.30258509299405	NA	2.02316539887035	1.91335700843514	0.109808390435209	1.0583341219437	1.37634122225202	0.0858445729265891	0.103755882153302	0.0797828246803043	0.894076891237891	NA	NA	NA	0.886061973276625	94.8961249770509
a552	TP53_mut	269	NSC-207895	MDM4	12	5	2.99573227355399	NA	3.15748078995874	3.02282639202611	0.134654397932633	1.79961061822721	2.07314689745318	0.0717599361614895	0.0748241850591436	0.0649516916037419	0.894551731170521	NA	NA	NA	0.902912375582482	94.8961249770509
a553	loss_cnaLIHC10_(RB1)	1371	PLX4720 (rescreen)	BRAF	3	13	2.30258509299405	NA	4.1385908858475	4.20296490765173	-0.0643740218042277	0.815771016314031	0.740131552055805	0.0856717076808187	0.0789118766379988	0.0869764592867593	0.895500081862603	NA	NA	NA	0.908695709252667	94.8961249770509
a554	loss_cnaLIHC7_(CDKN2A)	229	LY317615	PRKCB (PKCbeta)	4	13	2.99573227355399	2.32630161961136	3.99818205322447	4.12569665661109	-0.127514603386616	1.29373215459223	1.76075677642052	0.0760017865671465	0.0985633718184951	0.0724203394212365	0.896020864161528	NA	NA	NA	0.879530801418043	94.8961249770509
a555	loss_cnaLIHC10_(RB1)	230	GSK429286A	ROCK2	3	14	2.99573227355399	2.32630161961136	4.93068918670364	4.81644861317245	0.114240573531192	0.355439597687477	1.45530728323404	0.0839374780356541	0.321406433820126	0.0784992797379001	0.896790075311212	NA	NA	NA	0.798783045992877	94.8961249770509
a556	TP53_mut	1527	GDC0941 (rescreen)	PI3K	10	5	1.38629436111989	NA	0.749559032107822	0.8134801737387	-0.0639211416308778	0.719882074509117	1.17144661941238	0.0723293045242257	0.088793906522072	0.0545659875333817	0.896963048618982	NA	NA	NA	0.914824896257838	94.8961249770509
a557	loss_cnaLIHC10_(RB1)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	13	1.38629436111989	NA	1.37477006487054	1.45827125248282	-0.0835011876122809	0.518333190270068	1.08515533027861	0.0815774227599813	0.161095583265224	0.0769486038379798	0.900464605438231	NA	NA	NA	0.849690712856156	94.8961249770509
a558	TP53_mut	1373	Dabrafenib	BRAF	11	4	2.30258509299405	NA	3.74508489224445	3.82263268808579	-0.0775477958413364	1.14589510616801	0.693060953112405	0.0732462142966632	0.0676744279855287	0.111891739814635	0.902087663775899	NA	NA	NA	0.87750692618257	94.8961249770509
a559	loss_cnaLIHC7_(CDKN2A)	203	BMS-345541	IKBKB	4	13	2.77258872223978	NA	3.53555642838984	3.44011692399906	0.0954395043907765	1.51524997547467	1.28591518926257	0.0714935991427054	0.0629859798287601	0.0742191282813199	0.902153313582995	NA	NA	NA	0.91424747213976	94.8961249770509
a560	loss_cnaLIHC7_(CDKN2A)	1003	Camptothecin	TOP1	4	10	-2.30258509299405	NA	-3.4939065553571	-3.41547072067117	-0.0784358346859251	1.53027240320455	0.947338534158493	0.0699172384751623	0.051256125720932	0.0827959930455045	0.907878888270847	NA	NA	NA	0.928588158442804	94.8961249770509
a561	TP53_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	12	5	2.32630161961136	NA	2.06232912088593	1.88167479032289	0.180654330563045	2.81826740617988	3.23259560986005	0.0615626269219604	0.0641012028052795	0.0558852242489021	0.9094592764057	NA	NA	NA	0.916473440716106	94.8961249770509
a562	loss_cnaLIHC10_(RB1)	290	KIN001-260	IKK	3	14	2.99573227355399	NA	4.68407189310994	4.75943747675152	-0.075365583641589	0.685795378052857	1.07833013186102	0.0728428290133338	0.109895146647927	0.0698910114952648	0.910363844529977	NA	NA	NA	0.884371474909161	94.8961249770509
a563	loss_cnaLIHC10_(RB1)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	12	1.6094379124341	NA	1.17324789790424	1.11419636041251	0.059051537491736	0.735372967670053	0.814207214275009	0.0735768564720897	0.0803014797767644	0.0725264238100826	0.910991445346641	NA	NA	NA	0.91007601314332	94.8961249770509
a564	loss_cnaLIHC7_(CDKN2A)	299	OSI-027	MTORC1/2	4	13	2.99573227355399	NA	2.1076549146429	1.92092561458281	0.186729300060089	3.28664079691961	2.82116296322419	0.0639440036649957	0.0568146358540613	0.0661887677153837	0.912437198605122	NA	NA	NA	0.922738626338439	94.8961249770509
a565	TP53_mut	1021	Axitinib	PDGFR, KIT, VEGFR	10	4	0.693147180559945	NA	1.88580598617678	1.96350717211655	-0.0777011859397645	1.06164461831269	1.47385943968442	0.0659436679696121	0.0731894502166441	0.0527195361020329	0.913090221462724	NA	NA	NA	0.927854794652828	94.8961249770509
a566	loss_cnaLIHC7_(CDKN2A)	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	13	2.77258872223978	NA	0.772485712699961	0.886468417597583	-0.113982704897622	1.74898700234626	1.88870827663725	0.061228251139746	0.0651706986642635	0.060349555464734	0.916140593639402	NA	NA	NA	0.915032913756223	94.8961249770509
a567	TP53_mut	221	TAK-715	p38a	12	5	2.99573227355399	2.32630161961136	4.28194242512439	4.34197346129282	-0.0600310361684278	1.05165276595896	1.1455622732617	0.0557134715618076	0.0570825638571754	0.0524031190356022	0.918026486611254	NA	NA	NA	0.922534701743687	94.8961249770509
a568	loss_cnaLIHC7_(CDKN2A)	1021	Axitinib	PDGFR, KIT, VEGFR	4	10	0.693147180559945	NA	1.95884116930558	1.88767238730117	0.0711687820044169	0.232097668570906	1.35407857689519	0.0603946925952365	0.306632903478196	0.0525588272488602	0.920374708852891	NA	NA	NA	0.87568229031441	94.8961249770509
a569	TP53_mut	299	OSI-027	MTORC1/2	12	5	2.99573227355399	NA	1.91920832170406	2.07443055753988	-0.155222235835826	2.70967817461389	3.43399373740986	0.05315016242309	0.0572843805917814	0.0452016653801193	0.921784320787801	NA	NA	NA	0.931078719796614	94.8961249770509
a570	loss_cnaLIHC10_(RB1)	346	THZ-2-102-1	CDK7	3	13	0.916290731874155	2.99573227355399	-0.422776471847477	-0.574830560381427	0.15205408853395	2.47092894227865	2.38299614968998	0.0634681140000495	0.0615372161992355	0.0638079455368533	0.922472016526464	NA	NA	NA	0.929193501536305	94.8961249770509
a571	TP53_mut	282	EKB-569	EGFR	12	5	0.916290731874155	2.99573227355399	2.08786357356621	1.99741350392032	0.0904500696458863	1.24741714791531	2.62265223195612	0.0524375316864885	0.0725098815556985	0.0344880150497207	0.922829390028075	NA	NA	NA	0.944220553975231	94.8961249770509
a572	TP53_mut	286	KIN001-236	TIE2	12	5	2.32630161961136	NA	4.32274995996191	4.27730837416511	0.0454415857968051	0.858710093624051	0.921010444951052	0.0518883514578249	0.0529184251288186	0.0493388387134091	0.923634860307648	NA	NA	NA	0.927309145967454	94.8961249770509
a573	TP53_mut	1042	BIRB 0796	p38, JNK2	10	3	2.30258509299405	NA	3.95391062497284	3.90214407779411	0.0517665471787292	0.821643680594435	0.772148011544039	0.0636837774217701	0.0630036454990777	0.0670422592622019	0.924670925329463	NA	NA	NA	0.925565041742969	94.8961249770509
a574	loss_cnaLIHC10_(RB1)	265	Tubastatin A	HDAC6	3	14	2.99573227355399	NA	4.76674119944945	4.82763087232889	-0.0608896728794397	0.794156481564181	1.04039643516535	0.0602250612993886	0.0766721348914896	0.0585254532035785	0.925835974296818	NA	NA	NA	0.915537424895303	94.8961249770509
a575	loss_cnaLIHC10_(RB1)	1219	PFI-1	BRD2, BRD3, BRD4	3	13	2.30258509299405	NA	2.62804271720026	2.66964657930621	-0.0416038621059562	0.510416728417432	0.716704338735866	0.0602068530799647	0.0815095975301412	0.0580488492358477	0.92644284300698	NA	NA	NA	0.912346940511559	94.8961249770509
a576	TP53_mut	288	KIN001-055	JAK3, MNK1	12	5	2.32630161961136	NA	4.17712705071279	4.13777784543445	0.0393492052783389	0.71710645975494	0.977857827978054	0.0494929658088447	0.0548721946972641	0.0402402109514247	0.92714911651008	NA	NA	NA	0.937875837491968	94.8961249770509
a577	loss_cnaLIHC7_(CDKN2A)	1004	Vinblastine	Microtubules	4	10	-2.30258509299405	NA	-3.52248672417946	-3.59593965595156	0.0734529317720924	1.3128695692509	1.36556981603562	0.0543055028644637	0.0559483847386327	0.0537892174457498	0.928377036174163	NA	NA	NA	0.928667167771409	94.8961249770509
a578	loss_cnaLIHC7_(CDKN2A)	1005	Cisplatin	DNA crosslinker	4	10	1.79175946922805	2.30258509299405	2.89673002240294	2.95312447211077	-0.0563944497078355	0.759030458898428	1.1234590276978	0.0539999394933562	0.0742980061560113	0.0501971574552207	0.928778826604654	NA	NA	NA	0.916157942236677	94.8961249770509
a579	TP53_mut	1529	MLN4924	NEDD8-activating enzyme	10	4	0	NA	0.143699922266603	0.0736930685631483	0.0700068537034542	1.33126384942859	1.38321992954483	0.0520713423168423	0.0525867608690066	0.0506115131861143	0.931315240042733	NA	NA	NA	0.934219342038704	94.8961249770509
a580	loss_cnaLIHC10_(RB1)	1054	PD-0332991	CDK4, CDK6	3	11	1.38629436111989	0.693147180559945	2.01554889980384	1.94541385207869	0.0701350477251577	0.949641965355213	1.28637874592727	0.0567141985725059	0.0738542000920565	0.0545213048234886	0.932049396504261	NA	NA	NA	0.921532317163424	94.8961249770509
a581	loss_cnaLIHC10_(RB1)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	14	3.68887945411394	NA	3.91792466527442	3.82200924425088	0.0959154210235327	0.976256736930347	1.83307704521732	0.0550182751998918	0.0982481527606359	0.052324817046717	0.932230028423801	NA	NA	NA	0.902240666097901	94.8961249770509
a582	TP53_mut	196	Phenformin	AAPK1 (AMPK) agonist	11	5	8.29404964010203	NA	9.00870050113604	9.05566934813558	-0.0469688469995475	1.05914890071679	0.897193933279391	0.0462512559312251	0.0443458393505963	0.0523508299124011	0.932877773596348	NA	NA	NA	0.928986818404827	94.8961249770509
a583	TP53_mut	344	THZ-2-49	CDK9	12	4	2.99573227355399	NA	3.20382224942879	3.31820307428142	-0.114380824852622	2.31748293118377	2.38553994519559	0.0490434648274588	0.0493556277431552	0.0479475621789449	0.933507310181684	NA	NA	NA	0.936559987931419	94.8961249770509
a584	loss_cnaLIHC7_(CDKN2A)	1050	ZM-447439	AURKB	4	7	1.38629436111989	0.693147180559945	2.53406246587373	2.48818925960931	0.0458732062644165	0.887118365231511	0.878332938334274	0.0520534531338272	0.051710355756692	0.052227582801817	0.93563070887348	NA	NA	NA	0.936575556969226	94.8961249770509
a585	loss_cnaLIHC7_(CDKN2A)	1239	YK 4-279	RNA helicase A	3	12	2.30258509299405	NA	1.18882614401794	1.22285200690951	-0.0340258628915679	1.11336359759843	0.528198833195073	0.0520845639621962	0.0305613215349983	0.0644186634903103	0.93691822898776	NA	NA	NA	0.963171163245193	94.8961249770509
a586	loss_cnaLIHC10_(RB1)	266	Zibotentan, ZD4054	Endothelin A Receptor	3	14	2.99573227355399	NA	5.56858544910179	5.58309029469099	-0.0145048455891965	0.24839613553169	0.308708215444004	0.0481305226229898	0.0583940066464761	0.0469856157483036	0.940695688687307	NA	NA	NA	0.93494202858821	94.8961249770509
a587	TP53_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	11	5	2.99573227355399	NA	3.45292594636095	3.50681586090548	-0.0538899145445346	1.44723358945984	1.26491262696526	0.0385596967269839	0.0372365006844874	0.0426036655779345	0.944017777793969	NA	NA	NA	0.941537704277153	94.8961249770509
a588	loss_cnaLIHC7_(CDKN2A)	1529	MLN4924	NEDD8-activating enzyme	3	11	0	NA	0.0752922264031268	0.136899528882658	-0.0616073024795313	2.42410219666008	0.997134716714555	0.045818386637876	0.0254144823450157	0.0617843320935814	0.945077847231408	NA	NA	NA	0.969281203335359	94.8961249770509
a589	loss_cnaLIHC7_(CDKN2A)	193	GW-2580	CSF1R (cFMS)	4	13	2.99573227355399	NA	5.13926527688323	5.12019764095067	0.0190676359325588	0.411704259807298	0.516909268460328	0.0383152990703491	0.0463139146082277	0.0368877810787836	0.947457586146373	NA	NA	NA	0.941786424096942	94.8961249770509
a590	TP53_mut	1004	Vinblastine	Microtubules	10	4	-2.30258509299405	NA	-3.55959809702584	-3.61334062149374	0.0537425244678973	1.31443148082761	1.46190513018369	0.0397266486095023	0.0408865165296097	0.0367619781600633	0.947567915332945	NA	NA	NA	0.951479895574483	94.8961249770509
a591	loss_cnaLIHC7_(CDKN2A)	1149	TW 37	BCL2, BCL2L1	4	11	1.6094379124341	NA	-0.77354500176601	-0.806388291455958	0.0328432896899487	0.624295679704962	0.896721133804004	0.0390194273900764	0.0526085487336228	0.0366259793059892	0.947735109846221	NA	NA	NA	0.938597091379142	94.8961249770509
a592	loss_cnaLIHC10_(RB1)	223	ZSTK474	PI3K	3	14	1.63315443905142	2.32630161961136	1.42225400313962	1.34823602119134	0.0740179819482836	0.854964244306952	1.92589549608184	0.0406717246536963	0.0865743596193122	0.0384330209499272	0.94987152308176	NA	NA	NA	0.920103495917154	94.8961249770509
a593	loss_cnaLIHC7_(CDKN2A)	1248	FK866	NAMPT	4	11	0	NA	-1.22018787737992	-1.34225226195465	0.122064384574734	3.63926977621008	3.14247722542908	0.0373990079677746	0.0335409002577025	0.0388433633144523	0.949902330449445	NA	NA	NA	0.954979731323106	94.8961249770509
a594	loss_cnaLIHC10_(RB1)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	14	2.77258872223978	NA	4.74179561486293	4.70171545126332	0.040080163599618	0.76097571786198	1.01760888266756	0.040597658260414	0.052669438273571	0.0393866094157433	0.949962678771522	NA	NA	NA	0.942140845384946	94.8961249770509
a595	loss_cnaLIHC7_(CDKN2A)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	10	2.30258509299405	NA	1.07047498137781	1.0943696845768	-0.0238947031989867	0.438400674341262	0.753891614696607	0.0346951707347227	0.0545042574008142	0.031695143881661	0.95419972844065	NA	NA	NA	0.942676288553592	94.8961249770509
a596	TP53_mut	1052	RO-3306	CDK1	10	4	1.6094379124341	NA	3.23810111176706	3.21161934765167	0.0264817641153932	0.70395818674959	0.970045520584568	0.033992492011613	0.0376183765085087	0.0272995066246321	0.955126201390444	NA	NA	NA	0.962627858810606	94.8961249770509
a597	loss_cnaLIHC7_(CDKN2A)	1371	PLX4720 (rescreen)	BRAF	4	12	2.30258509299405	NA	4.17227562013802	4.19710116470524	-0.0248255445672143	1.19944654588272	0.571818259256442	0.0330216664606314	0.020697499736384	0.0434150959073884	0.955198005183888	NA	NA	NA	0.970354509159127	94.8961249770509
a598	loss_cnaLIHC10_(RB1)	329	QL-XI-92	DDR1	3	14	2.32630161961136	NA	4.21450909883961	4.24543331675284	-0.0309242179132312	0.513872128946474	0.911118918703667	0.0355977619428637	0.0601788191483183	0.0339409239325531	0.956117800831945	NA	NA	NA	0.938773342045331	94.8961249770509
a599	loss_cnaLIHC7_(CDKN2A)	1058	GDC0941	PI3K (class 1)	4	10	1.38629436111989	0.693147180559945	1.1742260597613	1.12780533390382	0.0464207258574831	1.76189041095245	1.32153561667133	0.0321413772940095	0.0263471130604478	0.0351263524583674	0.957567196722074	NA	NA	NA	0.964099437275453	94.8961249770509
a600	TP53_mut	1239	YK 4-279	RNA helicase A	10	5	2.30258509299405	NA	1.21007910321231	1.22798229656897	-0.0179031933566578	0.703713022253995	0.522707645574698	0.0274008138006473	0.0254410431390254	0.0342508733289598	0.960861496205143	NA	NA	NA	0.956790147479941	94.8961249770509
a601	loss_cnaLIHC7_(CDKN2A)	153	Midostaurin	KIT	4	13	-0.669430653942629	NA	-0.54912747440117	-0.511289445611961	-0.0378380287892085	2.18814941313942	1.0172560292035	0.0283175039038816	0.0172922509596458	0.0371961705833636	0.961153669610937	NA	NA	NA	0.975151462810383	94.8961249770509
a602	TP53_mut	254	AC220	FLT3	12	5	0.0237165266173161	NA	2.48131576913223	2.46580049619262	0.0155152729396093	0.704187986434907	0.493665359425841	0.0236982412204684	0.0220328566213668	0.0314287252353586	0.9650762054643	NA	NA	NA	0.959709930554638	94.8961249770509
a603	TP53_mut	1003	Camptothecin	TOP1	10	4	-2.30258509299405	NA	-3.42956836248057	-3.45866245083361	0.0290940883530442	1.14637206717683	1.04720142992338	0.0259212917982487	0.0253792718665015	0.0277827049521628	0.965772533255933	NA	NA	NA	0.96502101394922	94.8961249770509
a604	loss_cnaLIHC10_(RB1)	156	AZD6482	PI3Kbeta	3	14	1.63315443905142	NA	2.1806092517101	2.20785964696592	-0.0272503952558218	0.695256104040989	1.04446393198094	0.0271164760091113	0.0391947587334167	0.026090317167907	0.966565075105742	NA	NA	NA	0.958075963315411	94.8961249770509
a605	loss_cnaLIHC10_(RB1)	269	NSC-207895	MDM4	3	14	2.99573227355399	NA	3.15818869837485	3.10923823889364	0.0489504594812158	2.41236901401576	1.78099714037808	0.0260723176561447	0.0202914476171828	0.027484861357399	0.967851750359583	NA	NA	NA	0.975950409074243	94.8961249770509
a606	loss_cnaLIHC10_(RB1)	140	Vinorelbine	Microtubules	3	14	-2.74887219562247	NA	-3.68382954661037	-3.72649473317894	0.0426651865685646	1.42099486537987	1.74329867132673	0.0250404438191062	0.0300248703271415	0.0244738249792243	0.969123378581455	NA	NA	NA	0.966429143459611	94.8961249770509
a607	loss_cnaLIHC10_(RB1)	1194	SB-505124	TGFR1 (ALK5)	3	13	2.30258509299405	NA	3.89890646229885	3.87294799933971	0.0259584629591316	1.41563972513595	1.00549900396363	0.0241760698514855	0.018336913339048	0.025816497934662	0.970424036674991	NA	NA	NA	0.978263963105547	94.8961249770509
a608	loss_cnaLIHC7_(CDKN2A)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	13	-0.669430653942629	NA	-4.65959507922207	-4.70258649384777	0.0429914146256953	1.06902358482151	2.34996062286368	0.0199444825602942	0.0402155904098911	0.0182945255369027	0.972633881314933	NA	NA	NA	0.960165342777714	94.8961249770509
a609	TP53_mut	1495	AZD-2281	PARP1, PARP2	11	5	2.30258509299405	NA	3.71745275745425	3.72846435039805	-0.0110115929438024	0.633546008878597	0.908321435272107	0.0152348009551217	0.0173808891374651	0.0121230134137522	0.977864587195256	NA	NA	NA	0.981244368532592	94.8961249770509
a610	TP53_mut	1067	CCT007093	PPM1D	11	5	1.88706964903238	NA	4.31037326580355	4.31609248548105	-0.00571921967750288	0.429002993291384	0.205013087351055	0.0150993655670887	0.0133314213815248	0.0278968516176217	0.978061312802307	NA	NA	NA	0.971739625146583	94.8961249770509
a611	TP53_mut	235	QL-XII-47	BTK, BMX	12	5	2.32630161961136	NA	2.05101627132105	2.0161758543863	0.0348404169347503	2.56064707779122	1.93510007409673	0.0144580154320045	0.0136060987228288	0.0180044522767191	0.978688695012268	NA	NA	NA	0.976179757258142	94.8961249770509
a612	loss_cnaLIHC10_(RB1)	291	KIN001-266	MAP3K8 (COT)	3	14	2.99573227355399	NA	3.48536264602301	3.5048744645934	-0.0195118185703866	0.961205194748076	1.2830642138753	0.0156725630649982	0.0202993270084236	0.0152072034738263	0.980671394896765	NA	NA	NA	0.977667970283711	94.8961249770509
a613	loss_cnaLIHC7_(CDKN2A)	173	FH535	unknown 	4	13	3.46573590279973	NA	1.41317928033051	1.43123051442679	-0.0180512340962888	0.555959666534499	1.41775315929559	0.0139691441955227	0.0324686037186993	0.0127322827517151	0.980830619279024	NA	NA	NA	0.970646306342642	94.8961249770509
a614	loss_cnaLIHC10_(RB1)	1264	SGC0946	Q8TEK3 (DOT1L)	3	13	-0.693147180559945	NA	1.70774132173088	1.71321712451161	-0.00547580278073334	0.345709856880249	0.350507121983501	0.0156529403244237	0.015839301864714	0.0156225150283568	0.980848037362468	NA	NA	NA	0.981855721788785	94.8961249770509
a615	loss_cnaLIHC10_(RB1)	1175	AG-014699	PARP1, PARP2	3	12	1.6094379124341	NA	3.757600718639	3.76976157375681	-0.0121608551178065	0.945703240420951	0.739795853295458	0.0156905606963421	0.0128590604304089	0.0164381228465061	0.980976323498982	NA	NA	NA	0.984913212690368	94.8961249770509
a616	loss_cnaLIHC7_(CDKN2A)	178	BAY 61-3606	SYK	4	13	2.07944154167984	NA	2.11308135187873	2.13117604128486	-0.0180946894061238	2.14820951987251	1.34073532701656	0.0117761004640709	0.00842314924998453	0.0134960935551602	0.98383956237083	NA	NA	NA	0.988109584884179	95.0186026252714
a617	TP53_mut	268	YM155	BIRC5 (Survivin)	11	5	1.63315443905142	NA	-2.49328799173015	-2.47607656956775	-0.0172114221624016	3.3351378649585	3.78438493836647	0.00496087156533019	0.00516063289114309	0.004548010427774	0.992791180791168	NA	NA	NA	0.993269114054355	95.5920682313616
a618	loss_cnaLIHC10_(RB1)	154	CHIR-99021	GSK3B	3	14	0.940007258491471	NA	3.02939644868469	3.03462347471587	-0.00522702603117553	0.636510799750433	0.955959607019914	0.00568279092778741	0.00821199896879201	0.00546783147822546	0.99299089031117	NA	NA	NA	0.991210196177241	95.5920682313616
a619	loss_cnaLIHC10_(RB1)	263	FR-180204	ERK	3	14	2.99573227355399	NA	5.16420031220368	5.16697324620648	-0.00277293400280865	0.29562183740812	0.702179218871063	0.0041852701494835	0.00938000395072465	0.00394904025679778	0.99483788717072	NA	NA	NA	0.991547075623292	95.6151556520908
a620	loss_cnaLIHC10_(RB1)	1047	Nutlin-3a	MDM2	3	11	2.07944154167984	1.38629436111989	4.1346543105486	4.13243787460797	0.00221643594062204	1.11050009376084	1.15161861593439	0.00193597495011837	0.00199588991759183	0.00192462670362764	0.997677291874494	NA	NA	NA	0.997749723618083	95.7333963570596